Doxepin

Product NDC
10135-758
11-digit product format
101350758
Labeler code
10135
Product ID
10135-758_43029ddd-8941-add8-e063-6394a90a1e4d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Doxepin
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Marlex Pharmaceuticals, Inc.
Application
ANDA202337
Marketing category
ANDA
Marketing start
2023-10-01
Substance
DOXEPIN HYDROCHLORIDE
Active strength
3 mg/1
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202337-001DOXEPIN HYDROCHLORIDEDOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20
A202337-002DOXEPIN HYDROCHLORIDEDOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A202337-001AB
A202337-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20d06236e962d9…
2024-10-29 15:01 UTC2024-10A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-2079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-201e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-208072bd15b7f6…
2024-05-31 18:47 UTC2024-05A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-208072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-205c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-205c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-205d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-205d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-204b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-204b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORAL2016-01-2074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORAL2016-01-2074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202337-001DOXEPIN HYDROCHLORIDEEQ 3MG BASETABLET / ORALAB2016-01-20782e0a99824c…
2021-12-28 21:50 UTC2021-12A202337-002DOXEPIN HYDROCHLORIDEEQ 6MG BASETABLET / ORALAB2016-01-20782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 72 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202337-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A202337-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202337-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202337-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202337-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A202337-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202337-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202337-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202337-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202337-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202337-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202337-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202337-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202337-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202337-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202337-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202337-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202337-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202337-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A202337-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202337-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202337-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202337-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202337-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202337-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202337-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202337-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A202337-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202337-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202337-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202337-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A202337-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202337-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A202337-002AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A202337-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A202337-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202337-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A202337-002AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202337-001AB187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202337-002AB187673890dc5c…

Additional Listing Data#

Finished product
Yes
Brand name base
Doxepin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DOXEPIN HYDROCHLORIDE3 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3U9A0FE9N5Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
966787Internal RxNorm lookup
966793Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
06e79a65-1455-804e-e063-6394a90a2f3dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
f6fcd62d-384f-5faa-05d7-c5d5903c6c43Product name420250515
3d5463a5-d368-9c2b-b40c-0f2b688e406eProduct name920240805
750bc85a-c69c-4145-a865-3f1124677d16Product name320240321
eda77195-5c17-5c7f-a6a7-8c80d2f8ae5fProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
10135-758-30Doxepin30 in 1 BOTTLETABLET, FILM COATED303

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
10135-758-30EA - Each10135-75894d57ff8-051b-4256-a3e8-098bec29c70f12023-12-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
10135-758DOXEPIN TABLET, FILM COATED [MARLEX PHARMACEUTICALS, INC.]2Current NDC, 1 package rows20241004_06e79a65-1455-804e-e063-6394a90a2f3d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DoxepinDOXEPINNorth Star Rx LLC12edd5c6-c863-b83a-e063-6294a90a2f362025-12-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202337
application number: ANDA202337
DoxepinDOXEPINMarlex Pharmaceuticals, Inc.06e79a65-1455-804e-e063-6394a90a2f3d2025-11-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202337
application number: ANDA202337
ndc (product): 10135-758
DoxepinDOXEPINArchis Pharma LLCe3eac8e4-224e-4b7b-81d3-071301f914fa2024-01-04Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202337
application number: ANDA202337

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
966787doxepin 3 MG Oral TabletPSN06e79a65-1455-804e-e063-6394a90a2f3d3
966793doxepin 6 MG Oral TabletPSN06e79a65-1455-804e-e063-6394a90a2f3d3
966787doxepin 3 MG Oral TabletSCD06e79a65-1455-804e-e063-6394a90a2f3d3
966793doxepin 6 MG Oral TabletSCD06e79a65-1455-804e-e063-6394a90a2f3d3
966787doxepin 3 MG (as doxepin hydrochloride 3.39 MG) Oral TabletSY06e79a65-1455-804e-e063-6394a90a2f3d3
966793doxepin 6 MG (as doxepin hydrochloride 6.78 MG) Oral TabletSY06e79a65-1455-804e-e063-6394a90a2f3d3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
10135-758-301013507583030 TABLET, FILM COATED in 1 BOTTLE (10135-758-30) 2023-10-01NoNoCurrent