Afrin

Product NDC: 11523-1159
11-digit product format: 115231159
Labeler code: 11523
Product ID: 11523-1159_4526eae4-23d0-37f1-e063-6394a90a96cf
Type: HUMAN OTC DRUG
Nonproprietary name: Oxymetazoline hydrochloride
Dosage form: SPRAY, METERED
Route: NASAL
Labeler: Bayer HealthCare LLC.
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1975-07-14
Substance: OXYMETAZOLINE HYDROCHLORIDE
Active strength: .05 g/100mL
Pharmacologic classes: Imidazolines [CS], Increased Sympathetic Activity [PE], Vasoconstriction [PE], Vasoconstrictor [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Afrin
Brand name suffix: Original Pump Mist
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
OXYMETAZOLINE HYDROCHLORIDE	.05 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K89MJ0S5VY	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1000990	Internal RxNorm lookup
1000992	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
0f5ec576-f788-40aa-9088-0dd672e3cc7c	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e67be450-f8e4-4bc1-88bd-1259d379f55f	Product name	1	20210127
c53f3286-4062-4cf5-8355-399519c639a6	Product name	1	20170424
a993dfc5-f219-4460-bde6-30dd724d9ef0	Product name	1	20160818

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
11523-1159-1	AfrinOriginal Pump Mist	1 in 1 CARTON	SPRAY, METERED	1		10
11523-1159-1	AfrinOriginal Pump Mist	15 mL in 1 BOTTLE, PUMP	SPRAY, METERED	15		10

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
11523-1159-1	ML - Milliliter	11523-1159	07b66e3c-4f5f-4ac4-8eab-3fdd1f9813ac	1	2013-09-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Oxymetazoline hydrochloride	ACTIVE INGREDIENT	K89MJ0S5VY	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
Oxymetazoline	ACTIVE MOIETY	8VLN5B44ZY	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
benzalkonium chloride	INACTIVE INGREDIENT	F5UM2KM3W7	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
edetate disodium	INACTIVE INGREDIENT	7FLD91C86K	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
polyethylene glycols	INACTIVE INGREDIENT	3WJQ0SDW1A	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
povidones	INACTIVE INGREDIENT	FZ989GH94E	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
propylene glycol	INACTIVE INGREDIENT	6DC9Q167V3	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
sodium phosphate, dibasic	INACTIVE INGREDIENT	GR686LBA74	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
sodium phosphate, monobasic	INACTIVE INGREDIENT	3980JIH2SW	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1
water	INACTIVE INGREDIENT	059QF0KO0R	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [MSD CONSUMER CARE, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
11523-1159	AFRIN ORIGINAL PUMP MIST (OXYMETAZOLINE HYDROCHLORIDE) SPRAY, METERED [BAYER HEALTHCARE LLC.]	9	Current NDC, Legacy NDC, 2 package rows	20241208_0f5ec576-f788-40aa-9088-0dd672e3cc7c.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 68 of 177 · 3,534 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
cherry throat relief lozenges	BENZOCAINE	Zee Medical	499d0748-538f-678c-e054-00144ff8d46c	2025-12-23	Warnings	Exact identifier application number: M012
Guaiasorb DM	DEXTROMETHORPHAN HBR, GUAIFENESIN	NuCare Pharmaceuticals, Inc.	46a480c7-7092-b809-e063-6294a90a60cd	2025-12-23	Warnings	Exact identifier application number: M012
menthol cough drops	MENTHOL	Winco Foods	360a6304-206d-5475-e054-00144ff8d46c	2025-12-23	Warnings	Exact identifier application number: M012
menthol cough drops	MENTHOL	Winco Foods	36342d8c-34ab-6178-e054-00144ff8d46c	2025-12-23	Warnings	Exact identifier application number: M012
cherry cough drops	MENTHOL	Winco Foods	37244333-1307-5121-e054-00144ff8d46c	2025-12-23	Warnings	Exact identifier application number: M012
honey lemon cough drops	MENTHOL	Winco foods	37718c73-880e-4a5c-e054-00144ff8d46c	2025-12-23	Warnings	Exact identifier application number: M012
honey lemon cough drops	MENTHOL	Winco Foods	40676ddc-577f-5cc9-e054-00144ff88e88	2025-12-23	Warnings	Exact identifier application number: M012
Sugar Free Menthol Cough Drops	MENTHOL	Winco Foods	3788e8b6-ab9e-1513-e054-00144ff88e88	2025-12-23	Warnings	Exact identifier application number: M012
SAFETUSSIN Non Drowsy Cough plus chest congestion	DEXTROMETHORPHAN HYDROBROMIDE, AND GUAIFENESIN	KRAMER LABORATORIES	eeca6370-29ea-4540-8139-e8461d58a286	2025-12-23	Warnings	Exact identifier application number: M012
Tussin DM	DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN	Discount Drug Mart	dd31f86b-f59e-459a-8e5f-176828706a4a	2025-12-23	Warnings	Exact identifier application number: M012
Tussin CF	DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE	Discount Drug Mart	f8e7a08e-7422-4a1b-bfec-93e0b50d10cd	2025-12-23	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HCL 25 MG	Pioneer Life Sciences, LLC	ab45ae97-7951-4058-e053-2995a90a7b2e	2025-12-23	Warnings	Exact identifier application number: M012
Childrens Chest Congestion Relief Grape	GUAIFENESIN	Discount Drug Mart	3e5d245f-515c-4106-a855-fb97681b646a	2025-12-23	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HCL 25 MG	Pioneer Life Sciences, LLC	ab45ed16-86bb-3faf-e053-2995a90acfbc	2025-12-23	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HCL 25 MG	Pioneer Life Sciences, LLC	a7999da7-148a-4c6d-a2ea-0f4cc1d5b283	2025-12-23	Warnings	Exact identifier application number: M012
Safetussin High Blood Pressure and diabetes Cough, Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND GUAIFENESIN	KRAMER LABORATORIES	279e309c-040d-4001-808d-b7d986a9a1d8	2025-12-23	Warnings	Exact identifier application number: M012
Sinus PE Head Congestion and Flu Severe	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	76fd1f8e-2670-421c-a9e6-c8adefb7962e	2025-12-23	Warnings	Exact identifier application number: M012
Leader Cough Drops Vanilla Honey	MENTHOL	Cardinal Health 110, LLC. DBA Leader	1f6f1218-be7d-4b80-ad0d-eb4d1a54a1e2	2025-12-22	Warnings	Exact identifier application number: M012
Leader Throat Soothing Drops Creamy Strawberry	THROAT SOOTHING CREAMY STRAWBERRY	Cardinal Health 110, LLC. DBA Leader	26cd146a-6461-604f-e063-6394a90ac36e	2025-12-22	Warnings	Exact identifier application number: M012
MGC Health	COUGH DROPS CREAMY STRAWBERRY	Medical Group Care LLC	043a5e11-30c3-44cd-e063-6394a90a318b	2025-12-22	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
K89MJ0S5VY	OXYMETAZOLINE HYDROCHLORIDE	2315-02-8	OXYMETAZOLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1000992	Afrin 0.05 % Nasal Spray	PSN	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000990	oxymetazoline HCl 0.05 % Nasal Spray	PSN	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000992	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin]	SBD	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000990	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray	SCD	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000992	Afrin 0.05 % Nasal Spray	SY	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000992	Afrin 0.5 MG/ML Nasal Spray	SY	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10
1000990	oxymetazoline hydrochloride 0.05 % Nasal Spray	SY	0f5ec576-f788-40aa-9088-0dd672e3cc7c	10

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
11523-1159-1	11523115901	1 BOTTLE, PUMP in 1 CARTON (11523-1159-1) / 15 mL in 1 BOTTLE, PUMP	1975-07-14	0000-00-00	No	No	Current