oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin]
- RxCUI
- 1000992
- RxNorm name
- oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin]
- Display name
- AFRIN (Nasal)
- Full name
- oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin]
- Term type
- SBD
- Status
- Active
- Strength
- 0.05%
- Dose form
- Spray
- Route
- Nasal
- Updated
- 2026-10-27 17:45:24
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 092010
- Active start
- 092010
- Multiple ingredient
- NO
- Branded
- YES
Ingredients And Strength#
| Ingredient | Strength | Base | Basis of strength |
|---|---|---|---|
| oxymetazoline hydrochloride | 0.5 MG / 1 ML | oxymetazoline | oxymetazoline hydrochloride |
Dose Form Concepts#
| Dose form | RxCUI |
|---|---|
| Nasal Spray | 126542 |
Derived Ingredient Concepts#
| Ingredient | RxCUI |
|---|---|
| oxymetazoline | 7812 |
Source Vocabulary Codes#
| Code type | Values | Count | Category |
|---|---|---|---|
| PRESCRIBABLE | Y | 1 | ATTRIBUTES |
| RXNAV_STR | Afrin 0.05 % Nasal Spray | 1 | NAMES |
| RxNorm Name | oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] | 1 | NAMES |
| RxNorm Synonym | 2 linked values | 2 | NAMES |
| TTY | SBD | 1 | ATTRIBUTES |
| SPL_SET_ID | 13 linked values
| 13 | CODES |
| RxCUI | 1000992 | 1 | CODES |
| MMSL_CODE | BD4399 | 1 | CODES |
FDA NDC Products And Packages#
| Package NDC | Product NDC | Name | Labeler | Application |
|---|---|---|---|---|
| 11523-0034-1 | 11523-0034 | Afrin NoDrip Allergy Sinus Night oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-0073-1 | 11523-0073 | Afrin Allergy Sinus Nasal oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-0090-1 | 11523-0090 | Children Afrin No Drip Extra Moisturizing Stuffy Nose Pump Mist Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-0090-2 | 11523-0090 | Children Afrin No Drip Extra Moisturizing Stuffy Nose Pump Mist Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-0147-1 | 11523-0147 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1159-1 | 11523-1159 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1167-1 | 11523-1167 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1167-2 | 11523-1167 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1167-3 | 11523-1167 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1167-5 | 11523-1167 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1167-6 | 11523-1167 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1350-1 | 11523-1350 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC | M012 |
| 11523-1350-2 | 11523-1350 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC | M012 |
| 11523-1350-3 | 11523-1350 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC | M012 |
| 11523-1350-4 | 11523-1350 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC | M012 |
| 11523-1783-1 | 11523-1783 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1783-2 | 11523-1783 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-1783-3 | 11523-1783 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-3142-1 | 11523-3142 | Afrin No Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 11523-3220-1 | 11523-3220 | Afrin No-Drip Oxymetazoline hydrochloride | Bayer HealthCare LLC | M012 |
| 11523-7020-1 | 11523-7020 | Afrin Oxymetazoline hydrochloride | Bayer HealthCare LLC. | M012 |
| 50269-560-01 | 50269-560 | Afrin Original Nasal OXYMETAZOLINE HYDROCHLORIDE | JC World Bell Wholesale Co., Inc. | M012 |
| 50269-560-06 | 50269-560 | Afrin Original Nasal OXYMETAZOLINE HYDROCHLORIDE | JC World Bell Wholesale Co., Inc. | M012 |
| 66715-5880-0 | 66715-5880 | Afrin Original Oxymetazoline Hydrochloride | Lil' Drug Store Products, Inc. | M012 |
| 66715-7016-3 | 66715-7016 | Afrin Original Oxymetazoline Hydrochloride | Lil' Drug Store Products, Inc. | M012 |
| 67751-185-01 | 67751-185 | Afrin OXYMETAZOLINE HYDROCHLORIDE | Navajo Manufacturing Company Inc. | M012 |
Drugs@FDA Applications#
| Application | NDC | Name | Marketing category | Labeler |
|---|---|---|---|---|
| M012 | 11523-0034 | Afrin NoDrip Allergy Sinus Night oxymetazoline hydrochloride | OTC MONOGRAPH DRUG | Bayer HealthCare LLC. |
UNII Substances#
No records found.
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
DailyMed RxNorm Mappings#
| Set ID | RxNorm mappings | Terms | SPL version | Label | Effective |
|---|---|---|---|---|---|
| 346f32cb-74cb-4896-b770-76d5f829a17d | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 16 | Afrin ® No Drip Extra Moisturizing Extra Moisturizing | 20251205 |
| a79b5541-864b-412a-a085-96986ed6af59 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 14 | Afrin ® No Drip Severe Congestion | 20251205 |
| 530b2d27-5883-489e-87fa-90b45eb93b3c | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 12 | Afrin ® No Drip Original Pump Mist | 20251205 |
| 89c165ba-3ad5-49b5-a5bb-423dc8e15bad | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 12 | Afrin ® Original | 20251204 |
| 0f5ec576-f788-40aa-9088-0dd672e3cc7c | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 10 | Afrin ® Original Pump Mist | 20251204 |
| a49a506e-aca2-4af0-a50b-dca2c031e61d | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 9 | Afrin ® Severe Congestion | 20251205 |
| e3231869-8ddf-9d17-e053-2995a90ae6d5 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 8 | Children's Afrin ® No Drip Extra Moisturizing Stuffy Nose Pump Mist (Ages 6 & above) | 20251204 |
| b023a571-7e54-7c63-e053-2a95a90a0f78 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 7 | Afrin NoDrip Allergy Sinus Night UI1612461 | 20251204 |
| c2d903bf-5c51-82d7-e053-2995a90aea49 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 7 | Afrin Allergy Sinus Nasal Spray UI1612342 | 20251204 |
| a3f997c2-d6b5-d9d5-e053-2995a90a6f26 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 7 | Afrin No Drip Night Pump Mist UI 1612461 | 20241206 |
| 8a97c012-6a47-4607-9389-58a4eed17b08 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 6 | Afrin ® Original | 20241218 |
| 65bf1556-f234-9439-e053-2a91aa0a3194 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 5 | Afrin | 20241002 |
| 1387514f-3c4b-46d0-873c-9eedf9721327 | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 3 | Afrin Original Nasal Spray | 20231105 |
| af46c67d-f01f-83f8-e053-2a95a90aa70f | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 3 | Afrin Original Nasal Spray | 20231105 |
| 16c52c79-baec-87db-e063-6294a90a3b3b | Afrin 0.05 % Nasal Spray [PSN] · oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin] [SBD] · Afrin 0.05 % Nasal Spray [SY] · Afrin 0.5 MG/ML Nasal Spray [SY] | 4 | 2 | Afrin ® No Drip Original/Night Pump Mist Bundle Pack | 20251204 |
Recently Linked DailyMed Labels#
| Set ID | Title | Manufacturer | Effective |
|---|---|---|---|
| ecfa14b8-a3f3-4569-b489-c9e1a51cf09e | Afrin Original Nasal Spray | JC World Bell Wholesale Co., Inc. | 20260831 |
| ecfa14b8-a3f3-4569-b489-c9e1a51cf09e | Afrin Original Nasal Spray | JC World Bell Wholesale Co., Inc. | 20260820 |
| 346f32cb-74cb-4896-b770-76d5f829a17d | Afrin ® No Drip Extra Moisturizing Extra Moisturizing | Bayer HealthCare LLC. | 20251205 |
| a79b5541-864b-412a-a085-96986ed6af59 | Afrin ® No Drip Severe Congestion | Bayer HealthCare LLC | 20251205 |
| 530b2d27-5883-489e-87fa-90b45eb93b3c | Afrin ® No Drip Original Pump Mist | Bayer HealthCare LLC. | 20251205 |
| 3beb5839-7422-449d-e054-00144ff88e88 | Afrin No-Drip Allergy Sinus | Bayer HealthCare LLC | 20251205 |
| a49a506e-aca2-4af0-a50b-dca2c031e61d | Afrin ® Severe Congestion | Bayer HealthCare LLC. | 20251205 |
| 89c165ba-3ad5-49b5-a5bb-423dc8e15bad | Afrin ® Original | Bayer HealthCare LLC. | 20251204 |
| 0f5ec576-f788-40aa-9088-0dd672e3cc7c | Afrin ® Original Pump Mist | Bayer HealthCare LLC. | 20251204 |
| e3231869-8ddf-9d17-e053-2995a90ae6d5 | Children's Afrin ® No Drip Extra Moisturizing Stuffy Nose Pump Mist (Ages 6 & above) | Bayer HealthCare LLC. | 20251204 |
| b023a571-7e54-7c63-e053-2a95a90a0f78 | Afrin NoDrip Allergy Sinus Night UI1612461 | Bayer HealthCare LLC. | 20251204 |
| c2d903bf-5c51-82d7-e053-2995a90aea49 | Afrin Allergy Sinus Nasal Spray UI1612342 | Bayer HealthCare LLC. | 20251204 |
| 16c52c79-baec-87db-e063-6294a90a3b3b | Afrin ® No Drip Original/Night Pump Mist Bundle Pack | Bayer HealthCare LLC. | 20251204 |
| 8a97c012-6a47-4607-9389-58a4eed17b08 | Afrin ® Original | Lil' Drug Store Products, Inc. | 20241218 |
| a3f997c2-d6b5-d9d5-e053-2995a90a6f26 | Afrin No Drip Night Pump Mist UI 1612461 | Bayer HealthCare LLC. | 20241206 |
| 65bf1556-f234-9439-e053-2a91aa0a3194 | Afrin | Navajo Manufacturing Company Inc. | 20241002 |
| af46c67d-f01f-83f8-e053-2a95a90aa70f | Afrin Original Nasal Spray | Bayer HealthCare LLC. | 20231105 |
| 1387514f-3c4b-46d0-873c-9eedf9721327 | Afrin Original Nasal Spray | JC World Bell Wholesale Co., Inc. | 20231105 |
| 4e3c2507-3f39-39a5-e054-00144ff8d46c | Afrin ® No Drip Original Pump Mist | Delpharm Montreal Inc. | 20200724 |
| 4e2b9ebe-6343-0182-e054-00144ff8d46c | Afrin ® No Drip Extra Moisturizing | Delpharm Montreal Inc. | 20200724 |
| 4e2b2deb-e01a-5fe6-e054-00144ff8d46c | Afrin ® No Drip Severe Congestion | Delpharm Montreal Inc. | 20200724 |
Drug Classes#
| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|---|---|---|---|---|
| ATC | D11AX | Other dermatologicals | ATC1-4 | oxymetazoline | |
| ATC | S01GA | Sympathomimetics used as decongestants | ATC1-4 | oxymetazoline | |
| ATC | R01AB | Sympathomimetics, combinations excl. corticosteroids | ATC1-4 | oxymetazoline | |
| ATC | R01AA | Sympathomimetics, plain | ATC1-4 | oxymetazoline | |
| FDASPL | D048288 | Imidazolines | CHEM | has_chemical_structure | oxymetazoline |
| FDASPL | N0000192562 | Vasoconstrictor | EPC | has_epc | oxymetazoline |
| FDASPL | N0000175651 | Increased Sympathetic Activity | PE | has_pe | oxymetazoline |
| FDASPL | N0000009908 | Vasoconstriction | PE | has_pe | oxymetazoline |
| MEDRT | D010109 | Oxymetazoline | CHEM | has_ingredient | oxymetazoline hydrochloride |
| MEDRT | D010109 | Oxymetazoline | CHEM | has_ingredient | oxymetazoline |
| MEDRT | D003139 | Common Cold | DISEASE | may_treat | oxymetazoline hydrochloride |
| MEDRT | D003139 | Common Cold | DISEASE | may_treat | oxymetazoline |
| MEDRT | D003231 | Conjunctivitis | DISEASE | may_treat | oxymetazoline hydrochloride |
| MEDRT | D003231 | Conjunctivitis | DISEASE | may_treat | oxymetazoline |
| MEDRT | D012220 | Rhinitis | DISEASE | may_treat | oxymetazoline |
| MEDRT | D012220 | Rhinitis | DISEASE | may_treat | oxymetazoline hydrochloride |
| MEDRT | D012852 | Sinusitis | DISEASE | may_treat | oxymetazoline |
| MEDRT | D012852 | Sinusitis | DISEASE | may_treat | oxymetazoline hydrochloride |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | oxymetazoline |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | oxymetazoline hydrochloride |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | oxymetazoline |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | oxymetazoline hydrochloride |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | oxymetazoline |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | oxymetazoline hydrochloride |
Properties#
| Category | Property | Value |
|---|---|---|
| ATTRIBUTES | AVAILABLE_STRENGTH | 0.5 MG/ML |
| ATTRIBUTES | GENERAL_CARDINALITY | SINGLE |
| ATTRIBUTES | HUMAN_DRUG | US |
| ATTRIBUTES | RXNAV_HUMAN_DRUG | US |
| ATTRIBUTES | SCHEDULE | 0 |
| NAMES | Prescribable Synonym | Afrin 0.05 % Nasal Spray |
| SOURCES | Source | Gold Standard Alchemy |
| SOURCES | Source | Metathesaurus FDA Structured Product Labels |
| SOURCES | Source | Micromedex RED BOOK |
| SOURCES | Source | Multum MediSource Lexicon |