Afrin

Manufacturer: Bayer HealthCare LLC.
Effective date: 2025-12-04
Label type: HUMAN OTC DRUG LABEL
Version: 12
Source: full-release
Hydrated at: 2026-06-01 01:19:56

Label at a glance#

ProductAfrin Original

Active ingredientOXYMETAZOLINE HYDROCHLORIDE

Label structure10 sections

Indications and uses

temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies temporarily relieves sinus congestion and pressure shrinks swollen nasal membranes so you can breathe more freely

Dosage and administration

adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period. children under 6 years of age: ask a doctor. To spray, squeeze bottle quickly and firmly. Do not tilt head backward while spraying. Wipe nozzle clean after use.

Storage and handling

store between 20° to 25°C (68° to 77°F) retain carton for future reference on full labeling

Contacts and useful links#

PhoneLabel contact1-800-317-2165

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Oxymetazoline hydrochloride 0.05%

Purpose

OTC - PURPOSE SECTION

Nasal decongestant

Uses

INDICATIONS & USAGE SECTION

temporarily relieves nasal congestion due to:
- common cold
- hay fever
- upper respiratory allergies
temporarily relieves sinus congestion and pressure
shrinks swollen nasal membranes so you can breathe more freely

Warnings

WARNINGS SECTION

Ask a doctor before use if you have

OTC - ASK DOCTOR SECTION

heart disease
high blood pressure
diabetes
thyroid disease
trouble urinating due to an enlarged prostate gland

When using this product

OTC - WHEN USING SECTION

do not use more than directed
do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen.
temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur
use of this container by more than one person may spread infection

OTC - STOP USE SECTION

Stop use and ask a doctor if symptoms persist

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or breast-feeding, ask a health professional before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period.
children under 6 years of age: ask a doctor.

To spray, squeeze bottle quickly and firmly. Do not tilt head backward while spraying. Wipe nozzle clean after use.

Other information

STORAGE AND HANDLING SECTION

store between 20° to 25°C (68° to 77°F)
retain carton for future reference on full labeling

Inactive ingredients

INACTIVE INGREDIENT SECTION

benzalkonium chloride solution, edetate disodium, polyethylene glycol, povidone, propylene glycol, purified water, sodium phosphate dibasic, sodium phosphate monobasic

Questions or comments?

OTC - QUESTIONS SECTION

Call 1-800-317-2165

PRINCIPAL DISPLAY PANEL - 15 mL Bottle Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Afrin ^®

Oxymetazoline HCl Nasal Solution-Nasal Decongestant

Original

NASAL SPRAY

Fast, Powerful

Congestion

Relief

Colds • Allergies

up to 12

Hour

Relief

Maximum

Strength

#1 Doctor & Pharmacist

Recommended Brand

1/2 FL OZ (15 mL)

11523-1167

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1000992	Afrin 0.05 % Nasal Spray	PSN	12
1000990	oxymetazoline HCl 0.05 % Nasal Spray	PSN	12
1000992	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray [Afrin]	SBD	12
1000990	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray	SCD	12
1000992	Afrin 0.05 % Nasal Spray	SY	12
1000992	Afrin 0.5 MG/ML Nasal Spray	SY	12
1000990	oxymetazoline hydrochloride 0.05 % Nasal Spray	SY	12

DailyMed Pharmacologic Classes#

Class, Version, Type table
Class	Version	Type	Effective
OXYMETAZOLINE Pharmacologic Class Indexing	2	Indexing - Pharmacologic Class	20180813

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e67be450-f8e4-4bc1-88bd-1259d379f55f	Product name	1	20210127
c53f3286-4062-4cf5-8355-399519c639a6	Product name	1	20170424
a993dfc5-f219-4460-bde6-30dd724d9ef0	Product name	1	20160818

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
11523-1167-1	AfrinOriginal	6 mL in 1 BOTTLE, SPRAY	SPRAY	6	12
11523-1167-2	AfrinOriginal	21 mL in 1 BOTTLE, SPRAY	SPRAY	21	12
11523-1167-2	AfrinOriginal	2 in 1 CARTON	SPRAY	2	12
11523-1167-3	AfrinOriginal	1 in 1 CARTON	SPRAY	1	12
11523-1167-3	AfrinOriginal	20 mL in 1 BOTTLE, SPRAY	SPRAY	20	12
11523-1167-4	AfrinOriginal	3 in 1 CARTON	SPRAY	3	12
11523-1167-4	AfrinOriginal	30 mL in 1 BOTTLE, SPRAY	SPRAY	30	12
11523-1167-5	AfrinOriginal	30 mL in 1 BOTTLE, SPRAY	SPRAY	30	12
11523-1167-5	AfrinOriginal	1 in 1 CARTON	SPRAY	1	12
11523-1167-6	AfrinOriginal	15 mL in 1 BOTTLE, SPRAY	SPRAY	15	12
11523-1167-6	AfrinOriginal	1 in 1 CARTON	SPRAY	1	12

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
11523-1167-3	ML - Milliliter	11523-1167	e6b61680-eaad-4ff1-a0d4-d25116e1ada1	1	2015-10-02
11523-1167-5	ML - Milliliter	11523-1167	892df7b8-5889-48d3-9cdf-70a8f33e8c49	1	2013-10-17
11523-1167-6	ML - Milliliter	11523-1167	5797e12f-28cc-49e5-bfd1-5dc75045522c	1	2013-10-17

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Oxymetazoline hydrochloride	ACTIVE INGREDIENT	K89MJ0S5VY	2
Oxymetazoline	ACTIVE MOIETY	8VLN5B44ZY	2
benzalkonium chloride	INACTIVE INGREDIENT	F5UM2KM3W7	2
edetate disodium	INACTIVE INGREDIENT	7FLD91C86K	2
polyethylene glycols	INACTIVE INGREDIENT	3WJQ0SDW1A	2
povidones	INACTIVE INGREDIENT	FZ989GH94E	2
propylene glycol	INACTIVE INGREDIENT	6DC9Q167V3	2
sodium phosphate, dibasic	INACTIVE INGREDIENT	GR686LBA74	2
sodium phosphate, monobasic	INACTIVE INGREDIENT	3980JIH2SW	2
water	INACTIVE INGREDIENT	059QF0KO0R	2

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 11 matching rows.

Afrin Original
Oxymetazoline hydrochloride
SODIUM PHOSPHATE, DIBASIC
SODIUM PHOSPHATE, MONOBASIC
OXYMETAZOLINE
EDETATE DISODIUM
BENZALKONIUM CHLORIDE
POLYETHYLENE GLYCOL, UNSPECIFIED
POVIDONE
PROPYLENE GLYCOL
WATER

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
11523-1167	11523-1167-2, 11523-1167-3, 11523-1167-4, 11523-1167-5, 11523-1167-6, 11523-1167-1

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 9 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
SODIUM PHOSPHATE, DIBASIC	GR686LBA74	IACT
SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	IACT
OXYMETAZOLINE HYDROCHLORIDE	K89MJ0S5VY	ACTIB
EDETATE DISODIUM	7FLD91C86K	IACT
BENZALKONIUM CHLORIDE	F5UM2KM3W7	IACT
POLYETHYLENE GLYCOL, UNSPECIFIED	3WJQ0SDW1A	IACT
POVIDONE	FZ989GH94E	IACT
PROPYLENE GLYCOL	6DC9Q167V3	IACT
WATER	059QF0KO0R	IACT

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 7 · 392 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	SUSPENSION / OPHTHALMIC	0.43 %w/w		Exact identifier — unii candidate 98 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	INJECTION, SUSPENSION / SUBCUTANEOUS	0.07 %w/v		Exact identifier — unii candidate 63 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, COATED / ORAL	49.2 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	FILM, SOLUBLE / ORAL		9 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	INJECTION / INTRAVENOUS		161 mg	Exact identifier — unii candidate 63 equally ranked IID candidates
benzalkonium chloride	BENZALKONIUM CHLORIDE	F5UM2KM3W7	SPRAY / NASAL		1 mg	Exact identifier — unii+route+dosage form 7 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, COATED / ORAL	49.2 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET / SUBLINGUAL	6 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION / INTRAVENOUS	200 mg		Exact identifier — unii candidate 98 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	SYSTEM / IONTOPHORESIS	14.2 mg		Exact identifier — unii candidate 63 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	CAPSULE / ORAL		300 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SPRAY / NASAL		1 mg	Exact identifier — unii+route+dosage form 7 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SYSTEM / TOPICAL		41 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL		350 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS	13.2 mg		Exact identifier — unii candidate 63 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SPRAY / NASAL		5 mg	Exact identifier — unii+route+dosage form 7 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SUSPENSION/ DROPS / OPHTHALMIC	0.6 %w/v		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	SOLUTION / ORAL	40 mg/1ml		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SOLUTION / OPHTHALMIC	1.8 %w/v		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SUSPENSION/ DROPS / OPHTHALMIC	0.6 %w/v		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SYSTEM / TOPICAL		41 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION, POWDER, FOR SOLUTION / INTRAMUSCULAR	40 mg		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TROCHE / ORAL	30 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	SYRUP / ORAL		70 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SUSPENSION / ORAL	20 mg/5ml		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET / SUBLINGUAL	6 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SYSTEM / TOPICAL		41 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	CONCENTRATE / ORAL	17 mg/5ml		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	FILM, EXTENDED RELEASE / TRANSDERMAL	NA		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	FILM, EXTENDED RELEASE / TRANSDERMAL	NA		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, FILM COATED, EXTENDED RELEASE / ORAL	17 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / SUBCUTANEOUS	0.22 mg		Exact identifier — unii candidate 63 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, FOR SUSPENSION / ORAL	2 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SYSTEM / TOPICAL		41 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, FOR SUSPENSION / ORAL	2 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, FILM COATED, EXTENDED RELEASE / ORAL	17 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS	40 mg		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	CAPSULE, DELAYED RELEASE / ORAL	NA		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	FILM, SOLUBLE / ORAL		9 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, ORALLY DISINTEGRATING / ORAL	15.03 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION / SUBCUTANEOUS		14 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SPRAY / NASAL		1 mg	Exact identifier — unii+route+dosage form 7 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, COATED / ORAL	49.2 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	INJECTION, SUSPENSION / SUBCUTANEOUS	0.07 %w/v		Exact identifier — unii candidate 63 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TROCHE / ORAL	30 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / SUBCUTANEOUS	2.98 mg		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	POWDER, FOR SUSPENSION / ORAL	35 mg/5ml		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL		350 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS	40 mg		Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET, DELAYED RELEASE / ORAL		53 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	SYRUP / ORAL		70 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	TABLET / ORAL		216 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	SYSTEM / IONTOPHORESIS	14.2 mg		Exact identifier — unii candidate 63 equally ranked IID candidates
benzalkonium chloride	BENZALKONIUM CHLORIDE	F5UM2KM3W7	SPRAY / NASAL		1 mg	Exact identifier — unii+route+dosage form 7 equally ranked IID candidates
sodium phosphate, dibasic	SODIUM PHOSPHATE, DIBASIC	GR686LBA74	TABLET, EXTENDED RELEASE / ORAL		143 mg	Exact identifier — unii candidate 98 equally ranked IID candidates
sodium phosphate, monobasic	SODIUM PHOSPHATE, MONOBASIC	3980JIH2SW	SYSTEM / IONTOPHORESIS	14.2 mg		Exact identifier — unii candidate 63 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	SUSPENSION / OPHTHALMIC	1.8 %w/v		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	CAPSULE, EXTENDED RELEASE / ORAL		56 mg	Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	IMPLANT / SUBCUTANEOUS	6 mg		Exact identifier — unii candidate 210 equally ranked IID candidates
povidones	POVIDONE	FZ989GH94E	CAPSULE, EXTENDED RELEASE / ORAL		56 mg	Exact identifier — unii candidate 210 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Afrin Original	OXYMETAZOLINE HYDROCHLORIDE	Bayer HealthCare LLC.	89c165ba-3ad5-49b5-a5bb-423dc8e15bad	2025-12-04	Warnings	Exact identifier ndc (package): 11523-1167-2 ndc (package): 11523-1167-1 ndc (package): 11523-1167-4 ndc (package): 11523-1167-3 ndc (package): 11523-1167-5 ndc (package): 11523-1167-6 ndc (product): 11523-1167 ndc11 (package): 11523116705 ndc11 (package): 11523116702 ndc11 (package): 11523116703 ndc11 (package): 11523116701 ndc11 (package): 11523116706 ndc11 (package): 11523116704 spl id: 452362c1-c953-c5d7-e063-6294a90ad7c4 spl set id: 89c165ba-3ad5-49b5-a5bb-423dc8e15bad

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.