up and up
- Product NDC
- 11673-113
- 11-digit product format
- 116730113
- Labeler code
- 11673
- Product ID
- 11673-113_39fadcca-6c94-39b8-e063-6394a90a89a2
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Acetaminophen, Diphenhydramine hydrochloride, and Phenylephrine hydrochloride
- Dosage form
- POWDER, FOR SOLUTION
- Route
- ORAL
- Labeler
- Target Corporation
- Application
- M012
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2013-06-28
- Substance
- ACETAMINOPHEN; DIPHENHYDRAMINE HYDROCHLORIDE; PHENYLEPHRINE HYDROCHLORIDE
- Active strength
- 650; 25; 10 mg/1; mg/1; mg/1
- Pharmacologic classes
- Adrenergic alpha1-Agonists [MoA], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], alpha-1 Adrenergic Agonist [EPC]
- NDC exclude flag
- No
- Listing certified through
- 2026-12-31
- Current FDA listing
- Yes
Observed NDC auxiliary status history#
This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
| Captured / source date | Dataset | Scope | Package NDC | Snapshot | Source SHA-256 |
|---|---|---|---|---|---|
| 2024-11-09 02:27 UTC · source 2024-11-08 | excluded product | product | ad56d346431e… | cc804d4bbf1e… | |
| 2024-11-09 02:27 UTC · source 2024-11-08 | excluded package | package | 11673-113-07 | ad56d346431e… | cc804d4bbf1e… |
| 2024-10-04 04:10 UTC · source 2024-10-03 | excluded product | product | 367a005e9d99… | 383a685ebd0f… | |
| 2024-10-04 04:10 UTC · source 2024-10-03 | excluded package | package | 11673-113-07 | 367a005e9d99… | 383a685ebd0f… |
| 2024-07-10 04:00 UTC · source 2024-07-09 | excluded product | product | 557ba5c1ecfa… | 9c80585c8c6e… | |
| 2024-07-10 04:00 UTC · source 2024-07-09 | excluded package | package | 11673-113-07 | 557ba5c1ecfa… | 9c80585c8c6e… |
| 2024-05-28 21:12 UTC · source 2024-05-28 | excluded product | product | 8af77b9d5b6f… | d9bbb34c5368… | |
| 2024-05-28 21:12 UTC · source 2024-05-28 | excluded package | package | 11673-113-07 | 8af77b9d5b6f… | d9bbb34c5368… |
| 2024-05-15 03:39 UTC · source 2024-05-14 | excluded product | product | 834df4deac94… | adcc014656a3… | |
| 2024-05-15 03:39 UTC · source 2024-05-14 | excluded package | package | 11673-113-07 | 834df4deac94… | adcc014656a3… |
| 2024-03-11 06:39 UTC · source 2024-03-08 | excluded product | product | 1332a3947898… | d4bfe170f9cd… | |
| 2024-03-11 06:39 UTC · source 2024-03-08 | excluded package | package | 11673-113-07 | 1332a3947898… | d4bfe170f9cd… |
| 2022-08-30 03:57 UTC · source 2022-08-29 | excluded product | product | fb8cb913e6d1… | eb8c232b6be0… | |
| 2022-08-30 03:57 UTC · source 2022-08-29 | excluded package | package | 11673-113-07 | fb8cb913e6d1… | eb8c232b6be0… |
| 2022-04-09 23:13 UTC · source 2022-04-08 | excluded product | product | 86f5da6cb304… | a595104c45d7… | |
| 2022-04-09 23:13 UTC · source 2022-04-08 | excluded package | package | 11673-113-07 | 86f5da6cb304… | a595104c45d7… |
| 2022-04-04 05:40 UTC · source 2022-04-01 | excluded product | product | bd6a592717d7… | 303034d00443… | |
| 2022-04-04 05:40 UTC · source 2022-04-01 | excluded package | package | 11673-113-07 | bd6a592717d7… | 303034d00443… |
| 2021-12-27 23:28 UTC · source 2021-12-27 | excluded product | product | 8dfbde2a14a4… | c9ff85d89658… | |
| 2021-12-27 23:28 UTC · source 2021-12-27 | excluded package | package | 11673-113-07 | 8dfbde2a14a4… | c9ff85d89658… |
| 2020-12-18 03:04 UTC · source 2020-12-17 | excluded product | product | e2bbac7714bc… | 27bdfed8d636… | |
| 2020-12-18 03:04 UTC · source 2020-12-17 | excluded package | package | 11673-113-07 | e2bbac7714bc… | 27bdfed8d636… |
| 2020-06-10 20:45 UTC · source 2020-06-10 | excluded product | product | 9bebd1f3094a… | 5416666fcb17… | |
| 2020-06-10 20:45 UTC · source 2020-06-10 | excluded package | package | 11673-113-07 | 9bebd1f3094a… | 5416666fcb17… |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- up and up
- Brand name suffix
- nighttime flu and severe cold and cough
- Listing expiration
- 2026-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| ACETAMINOPHEN | 650 mg/1 |
| DIPHENHYDRAMINE HYDROCHLORIDE | 25 mg/1 |
| PHENYLEPHRINE HYDROCHLORIDE | 10 mg/1 |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| 362O9ITL9D | Internal UNII lookup |
| TC2D6JAD40 | Internal UNII lookup |
| 04JA59TNSJ | Internal UNII lookup |
Harmonized RxCUI identifiers#
| Identifier | FDA.report destination |
|---|---|
| 1659960 | Internal RxNorm lookup |
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| df488727-b913-440b-9a0b-cce3ae143bf2 | Available on FDA.report |
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| 0e2e0f88-b076-afe1-4bdd-32bca4375bec | Product name | 3 | 20250127 |
| 3e48c9c4-918d-5d23-2f0b-d2398b06be54 | Product name | 1 | 20140508 |
| 865c72dd-0d94-daac-f728-ddd4ded2a79e | Product name | 1 | 20140508 |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 11673-113-07 | 2024-11-12 | C162847 | 48780-1 | 9d75b9d1-20c7-f424-e053-dadaa90a57ce | up & up nighttime flu and severe cold and cough |
| 11673-113-07 | 2020-01-31 | C162847 | 48780-1 | 9d75b9d1-20c7-f424-e053-dadaa90a57ce | up & up nighttime flu and severe cold and cough |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 11673-113-07 | up and upnighttime flu and severe cold and cough | 6 in 1 CARTON | POWDER, FOR SOLUTION | 6 | 4 |
DailyMed Socrata Ingredients#
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 11673-113 | UP AND UP NIGHTTIME FLU AND SEVERE COLD AND COUGH (ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE, AND PHENYLEPHRINE HYDROCHLORIDE) POWDER, FOR SOLUTION [TARGET CORPORATION] | 3 | Current NDC, Legacy NDC, 1 package rows | 20241114_df488727-b913-440b-9a0b-cce3ae143bf2.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Flu HBP Maximum Strength | ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR | Rite Aid Corporation | f1a4ee57-33a3-4791-a769-b208b38acb72 | 2026-07-13 | Warnings | M012 |
| GOOD NEIGHBOR PHARMACY Childrens Allergy Relief | DIPHENHYDRAMINE HCL | AMERISOURCE BERGEN | c499574c-f32b-4608-bf8b-51ad44e35725 | 2026-07-13 | Warnings | M012 |
| Good NeighborChildrens Allergy Relief Bubblegum flavor | DIPHENHYDRAMINE HCL | AMERISOURCE BERGEN | f442c61b-7d2c-401c-b862-acbe2282927b | 2026-07-13 | Warnings | M012 |
| Sanatos | MENTHOL | Pharmadel LLC | 5683b099-f029-2d08-e063-6394a90ad482 | 2026-07-13 | Warnings | M012 |
| Cold and Flu Relief Nighttime | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | f673cdeb-4f8b-46b4-be92-c725d74abc55 | 2026-07-13 | Warnings | M012 |
| Cold Multi-Symptom | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL | ARMY AND AIR FORCE EXCHANGE SERVICE | e4fca5ba-2d45-4c38-b0fd-297159d1705a | 2026-07-13 | Warnings | M012 |
| Good Neighbor Sugar Free Adult Tussin DM Cough and Chest Congestion | DEXTROMETHORPHAN HBR, GUAIFENESIN | AMERISOURCE BERGEN | 0269c0fd-0d8f-4264-9025-d4dcb3c45c60 | 2026-07-13 | Warnings | M012 |
| Propolis Cooling Relief Cherry Cough Drops | MENTHOL, UNSPECIFIED FORM | Beekeeper's Naturals USA Inc | 7087566d-f24a-4508-aa25-7f42d055c43e | 2026-07-13 | Warnings | M012 |
| Sinus Pressure and Congestion Relief | DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL | Rite Aid Corporation | 35bcf263-3296-4d9c-84c0-146a173d6e87 | 2026-07-13 | Warnings | M012 |
| Good Neighbor Childrens Cough Relief Cherry Flavor | DEXTROMETHORPHAN HYDROBROMIDE AND GUAIFENESIN | AMERISOURCE BERGEN | a8e2fd43-b801-41ae-8d79-8ecf4a771543 | 2026-07-13 | Warnings | M012 |
| Good Neighbor No Drip Nasal Mist Extra Moisturizing | OXYMETAZOLINE HYDROCHLORIDE | AMERISOURCE BERGEN | 7872aadd-b23c-431f-8048-24eece25ca2d | 2026-07-13 | Warnings | M012 |
| Good Neighbor Dye Free Adult Tussin DM Cough and Chest Congestion | DEXTROMETHORPHAN HYDROBROMIDE AND GUAIFENESIN | AMERISOURCE BERGEN | 404a3521-8340-4476-a068-0e69cd0e514f | 2026-07-13 | Warnings | M012 |
| Daytime Cold and Flu | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | 8a8bd1e3-f3ce-484b-a98c-2cf3f03f1ab5 | 2026-07-13 | Warnings | M012 |
| Good Neighbor Long Acting Cough Adult Tussin | DEXTROMETHORPHAN HBR | AMERISOURCE BERGEN | df3c76bd-bd5b-42d7-a5f1-560fd3cba646 | 2026-07-13 | Warnings | M012 |
| Good Neighbor Adult Tussin Mucus and chest congestion | GUAIFENESIN | AMERISOURCE BERGEN | 97e9cd18-dd55-4a26-80e3-4c17b9e1a1e8 | 2026-07-13 | Warnings | M012 |
| GOOD NEIGHBOR PHARMACY No Drip Nasal Mist | OXYMETAZOLINE HYDROCHLORIDE | AMERISOURCE BERGEN | a217ca8a-1c00-4816-bc26-cc0f71c80c90 | 2026-07-13 | Warnings | M012 |
| Severe Congestion and Cough | DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL | Walgreen Company | 1ddc04fb-069c-44fe-814b-ba4f503c4be0 | 2026-07-10 | Warnings | M012 |
| COUGH DROPS- menthol granule | MENTHOL GRANULE | Anhui Jiuhe Health Industry Co., Ltd | 5351b943-5830-e4e7-e063-6394a90a5b66 | 2026-07-10 | Warnings | M012 |
| ValuMeds Nasal Decongestant PE Phenylephrine | PHENYLEPHRINE HYDROCHLORIDE | Cabinet Health P.B.C. | 3f284420-87c1-4c17-99e5-bc569bf9d45f | 2026-07-10 | Warnings | M012 |
| Severe Congestion and Cough Multi-Symptom Maximum Strength | DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL | CVS Pharmacy | 707eb066-cdfc-444b-833a-9d6d133d48e4 | 2026-07-10 | Warnings | M012 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1659960 | acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Granules for Oral Solution | PSN | df488727-b913-440b-9a0b-cce3ae143bf2 | 4 |
| 1659960 | acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution | SCD | df488727-b913-440b-9a0b-cce3ae143bf2 | 4 |
| 1659960 | acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packet for Oral Solution | SY | df488727-b913-440b-9a0b-cce3ae143bf2 | 4 |
| 1659960 | acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution | SY | df488727-b913-440b-9a0b-cce3ae143bf2 | 4 |
| 1659960 | APAP 650 MG / Diphenhydramine Hydrochloride 25 MG / Phenylephrine Hydrochloride 10 MG Granules for Oral Solution | SY | df488727-b913-440b-9a0b-cce3ae143bf2 | 4 |
Packages#
| Package NDC | 11-digit format | Description | Marketing start | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|
| 11673-113-07 | 11673011307 | 6 POWDER, FOR SOLUTION in 1 CARTON (11673-113-07) | 2013-06-28 | No | No | Current |