Carbon Dioxide

Product NDC: 12213-900
Requested package NDC: 12213-900-19
11-digit product format: 122130900
Labeler code: 12213
Product ID: 12213-900_5258724d-908c-07dc-e063-6394a90a01a1
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Carbon Dioxide
Dosage form: GAS
Route: RESPIRATORY (INHALATION)
Labeler: NexAir, LLC
Application: NDA215007
Marketing category: NDA
Marketing start: 1996-06-01
Substance: CARBON DIOXIDE
Active strength: 991 mL/L
Pharmacologic classes: Radiographic Contrast Agent [EPC], X-Ray Contrast Activity [MoA]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	12213-900	12213-900-19	D	Discontinued by firm		2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source date	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	`557ba5c1ecfa…`	`9c80585c8c6e…`

Source provenance: Browse the complete Orange Book source catalog.

Additional Listing Data#

Finished product: Yes
Brand name base: Carbon Dioxide
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CARBON DIOXIDE	991 mL/L

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
142M471B3J	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1091094	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
b0a1e508-3610-3b44-e053-2995a90ac6e2	Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
12213-900-11	Carbon Dioxide	566 L in 1 CYLINDER	GAS	566	9
12213-900-12	Carbon Dioxide	12385 L in 1 CYLINDER	GAS	12385	9
12213-900-13	Carbon Dioxide	990 L in 1 CYLINDER	GAS	990	9
12213-900-19	Carbon Dioxide	24750 L in 1 CYLINDER	GAS	24750	9
12213-900-25	Carbon Dioxide	24678 L in 1 CYLINDER	GAS	24678	9
12213-900-26	Carbon Dioxide	12339 L in 1 CYLINDER	GAS	12339	9
12213-900-27	Carbon Dioxide	180 L in 1 DEWAR	GAS	180	9
12213-900-28	Carbon Dioxide	4951 L in 1 CYLINDER	GAS	4951	9
12213-900-29	Carbon Dioxide	18564 L in 1 CYLINDER	GAS	18564	9
12213-900-30	Carbon Dioxide	1641 L in 1 CYLINDER	GAS	1641	9
12213-900-53	Carbon Dioxide	1238 L in 1 CYLINDER	GAS	1238	9
12213-900-58	Carbon Dioxide	1584 L in 1 CYLINDER	GAS	1584	9

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
12213-900	CARBON DIOXIDE GAS [NEXAIR, LLC]	7	Current NDC, Legacy NDC, 12 package rows	20241114_b0a1e508-3610-3b44-e053-2995a90ac6e2.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Carbon Dioxide	CARBON DIOXIDE	NexAir, LLC	b0a1e508-3610-3b44-e053-2995a90ac6e2	2026-05-21		Exact identifier application applno (NDA): 215007 application number: NDA215007 ndc (package): 12213-900-19 ndc (product): 12213-900 ndc11 (package): 12213090019

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
142M471B3J	CARBON DIOXIDE	124-38-9	CARBON DIOXIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1091094	carbon dioxide 99.1 % Gas for Inhalation	PSN	b0a1e508-3610-3b44-e053-2995a90ac6e2	9
1091094	carbon dioxide 99.1 % Gas for Inhalation	SCD	b0a1e508-3610-3b44-e053-2995a90ac6e2	9

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
12213-900-19	12213090019	24750 L in 1 CYLINDER (12213-900-19)	24750 l	1996-06-01	0000-00-00	No	No	Current