Lofexidine

Product NDC
14445-146
Requested package NDC
14445-146-36
11-digit product format
144450146
Labeler code
14445
Product ID
14445-146_d60a5ecb-5e15-4ea7-bc53-a3740f00adff
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lofexidine
Dosage form
TABLET, COATED
Route
ORAL
Labeler
Indoco Remedies Limited
Application
ANDA218613
Marketing category
ANDA
Marketing start
2024-08-21
Substance
LOFEXIDINE HYDROCHLORIDE
Active strength
.18 mg/1
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218613-001LOFEXIDINE HYDROCHLORIDELOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A218613-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218613-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2024-08-20a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A218613-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218613-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A218613-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218613-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218613-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218613-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218613-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218613-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218613-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218613-001AB1d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218613-001AB1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218613-001CGT2025-02-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A218613-001CGT2025-02-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218613-001CGT2025-02-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218613-001CGT2025-02-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218613-001CGT2025-02-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218613-001CGT2025-02-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218613-001CGT2025-02-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218613-001CGT2025-02-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218613-001CGT2025-02-24d06236e962d9…

Additional Listing Data#

Finished product
Yes
Brand name base
Lofexidine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LOFEXIDINE HYDROCHLORIDE.18 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V47G1SDI1BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2046591Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ed7613f5-ac52-4108-afb7-d92c818d6e3cAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3e49fde7-51ed-4b66-8350-88f7c4d066d4Product name220250317

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
14445-146-36Lofexidine1 in 1 CARTONTABLET, COATED13
14445-146-36Lofexidine36 in 1 BOTTLETABLET, COATED363
14445-146-96Lofexidine96 in 1 BOTTLETABLET, COATED963
14445-146-96Lofexidine1 in 1 CARTONTABLET, COATED13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
14445-146LOFEXIDINE TABLET, COATED [INDOCO REMEDIES LIMITED ]3Current NDC, 4 package rows20240822_ed7613f5-ac52-4108-afb7-d92c818d6e3c.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LofexidineLOFEXIDINEFlorida Pharmaceutical Products, LLCce4488e2-842c-45ba-aca7-075a900e2a1c2026-05-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218613
application number: ANDA218613
LofexidineLOFEXIDINEIndoco Remedies Limiteded7613f5-ac52-4108-afb7-d92c818d6e3c2024-08-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218613
application number: ANDA218613
ndc (package): 14445-146-36
ndc (product): 14445-146
ndc11 (package): 14445014636

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2046591lofexidine 0.18 MG Oral TabletPSNed7613f5-ac52-4108-afb7-d92c818d6e3c3
2046591lofexidine 0.18 MG Oral TabletSCDed7613f5-ac52-4108-afb7-d92c818d6e3c3
2046591lofexidine 0.18 MG (as lofexidine HCl 0.2 MG) Oral TabletSYed7613f5-ac52-4108-afb7-d92c818d6e3c3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
14445-146-36144450146361 BOTTLE in 1 CARTON (14445-146-36) / 36 TABLET, COATED in 1 BOTTLE1 bottle2024-08-21NoNoCurrent