Methylene Blue

Product NDC
14789-119
11-digit product format
147890119
Labeler code
14789
Product ID
14789-119_2a32783c-572a-26cb-e063-6394a90af066
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methylene Blue
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Nexus Pharmaceuticals, LLC
Application
ANDA217561
Marketing category
ANDA
Marketing start
2025-02-01
Substance
METHYLENE BLUE
Active strength
5 mg/mL
Pharmacologic classes
Oxidation-Reduction Activity [MoA], Oxidation-Reduction Agent [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217561-001METHYLENE BLUEMETHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217561-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-212680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217561-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217561-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217561-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217561-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217561-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217561-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217561-001AP12680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217561-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Methylene Blue
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHYLENE BLUE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
T42P99266KInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1788984Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3484312e-ff43-4425-98e8-cd2ecf9f2a6dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c39b72c3-7732-4ed2-a995-e6aa3a665a54Product name320250819

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
14789-119-05Methylene Blue5 in 1 CARTONINJECTION, SOLUTION58
14789-119-07Methylene Blue10 mL in 1 VIAL, GLASSINJECTION, SOLUTION108

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
14789-119-05ML - Milliliter14789-119163b03fd-8ba7-45c0-b1de-c49143f9f65112025-05-14
14789-119-07ML - Milliliter14789-119ffb3260b-513d-4cd7-81e9-13e281b33b0412025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
14789-119METHYLENE BLUE INJECTION, SOLUTION [NEXUS PHARMACEUTICALS, LLC]8Current NDC, 2 package rows20250201_3484312e-ff43-4425-98e8-cd2ecf9f2a6d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methylene BlueMETHYLENE BLUEOLIC (Thailand) Limitedd115faab-577f-4299-87ed-8d4f909b46592026-04-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217561
application number: ANDA217561
Methylene BlueMETHYLENE BLUENexus Pharmaceuticals, LLC3484312e-ff43-4425-98e8-cd2ecf9f2a6d2024-12-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217561
application number: ANDA217561
ndc (product): 14789-119

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1788984methylene blue 50 MG in 10 ML InjectionPSN3484312e-ff43-4425-98e8-cd2ecf9f2a6d8
178898410 ML methylene blue 5 MG/ML InjectionSCD3484312e-ff43-4425-98e8-cd2ecf9f2a6d8
1788984methylene blue 50 MG per 10 ML InjectionSY3484312e-ff43-4425-98e8-cd2ecf9f2a6d8

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
14789-119-05147890119055 VIAL, GLASS in 1 CARTON (14789-119-05) / 10 mL in 1 VIAL, GLASS (14789-119-07) 2025-02-01NoNoCurrent
14789-119-071478901190710 mL in 1 VIAL, GLASS10 mlHistorical