Tacrolimus

Product NDC
14789-135
11-digit product format
147890135
Labeler code
14789
Product ID
14789-135_44fc0987-ff9d-3099-e063-6394a90a7a55
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tacrolimus
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Nexus Pharmaceuticals, LLC
Application
ANDA217108
Marketing category
ANDA
Marketing start
2025-12-01
Substance
TACROLIMUS
Active strength
5 mg/mL
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC], Calcineurin Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217108-001TACROLIMUSTACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-12

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217108-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-12011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-12b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217108-001TACROLIMUSEQ 5MG BASE/MLINJECTABLE / INJECTIONAP2025-02-12a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217108-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217108-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217108-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217108-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217108-001AP1b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217108-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Tacrolimus
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TACROLIMUS5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WM0HAQ4WNMInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
198379Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9d502961-e9c0-4611-92bf-ce742a7b962cAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
df369ad4-19d8-393a-de46-8c6255b8b360Product name820251120
d2a74186-7b26-dbcc-9435-50b3d0be14abProduct name220250114
a64835ae-fa9d-41d8-9a93-36828ba72b96Product name320190611
b4a869e4-9fcd-47bd-95e3-85e7c75f8badProduct name120150819

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
14789-135-05Tacrolimus10 in 1 CARTONINJECTION1011
14789-135-07Tacrolimus1 mL in 1 VIALINJECTION111

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
14789-135-05ML - Milliliter14789-135713f1a9e-2075-44b6-8c4b-78d446fe688f12025-12-16
14789-135-07ML - Milliliter14789-1350398a10c-8ff6-4d39-b636-aabaafa8ef3112025-12-16

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TacrolimusTACROLIMUSNexus Pharmaceuticals, LLC9d502961-e9c0-4611-92bf-ce742a7b962c2025-12-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217108
application number: ANDA217108
ndc (product): 14789-135

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
198379tacrolimus 5 MG in 1 ML InjectionPSN9d502961-e9c0-4611-92bf-ce742a7b962c11
1983791 ML tacrolimus 5 MG/ML InjectionSCD9d502961-e9c0-4611-92bf-ce742a7b962c11
198379tacrolimus 5 MG per 1 ML InjectionSY9d502961-e9c0-4611-92bf-ce742a7b962c11

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
14789-135-051478901350510 VIAL in 1 CARTON (14789-135-05) / 1 mL in 1 VIAL (14789-135-07) 10 vial2025-12-01NoNoCurrent
14789-135-07147890135071 mL in 1 VIAL1 mlHistorical