Methylene Blue

Product NDC
15243-344
11-digit product format
152430344
Labeler code
15243
Product ID
15243-344_4e6a3ce6-7aa3-4480-e063-6294a90a9332
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
METHYLENE BLUE
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
OLIC (Thailand) Limited
Application
ANDA217561
Marketing category
ANDA
Marketing start
2025-02-01
Substance
METHYLENE BLUE
Active strength
5 mg/mL
Pharmacologic classes
Oxidation-Reduction Activity [MoA], Oxidation-Reduction Agent [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217561-001METHYLENE BLUEMETHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217561-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-212680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217561-001METHYLENE BLUE50MG/10ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-11-21a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217561-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217561-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217561-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217561-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217561-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217561-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217561-001AP12680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217561-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Methylene Blue
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHYLENE BLUE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
T42P99266KInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1788984Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d115faab-577f-4299-87ed-8d4f909b4659Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c39b72c3-7732-4ed2-a995-e6aa3a665a54Product name320250819

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
15243-344-05Methylene Blue5 in 1 CARTONINJECTION, SOLUTION51
15243-344-07Methylene Blue10 mL in 1 VIAL, GLASSINJECTION, SOLUTION101

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methylene BlueMETHYLENE BLUEOLIC (Thailand) Limitedd115faab-577f-4299-87ed-8d4f909b46592026-04-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217561
application number: ANDA217561
ndc (product): 15243-344
Methylene BlueMETHYLENE BLUENexus Pharmaceuticals, LLC3484312e-ff43-4425-98e8-cd2ecf9f2a6d2024-12-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217561
application number: ANDA217561

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1788984methylene blue 50 MG in 10 ML InjectionPSNd115faab-577f-4299-87ed-8d4f909b46591
178898410 ML methylene blue 5 MG/ML InjectionSCDd115faab-577f-4299-87ed-8d4f909b46591
1788984methylene blue 50 MG per 10 ML InjectionSYd115faab-577f-4299-87ed-8d4f909b46591

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
15243-344-05152430344055 VIAL, GLASS in 1 CARTON (15243-344-05) / 10 mL in 1 VIAL, GLASS (15243-344-07) 2025-02-01NoNoCurrent
15243-344-071524303440710 mL in 1 VIAL, GLASS10 mlHistorical