AZELEX

Product NDC
16110-869
11-digit product format
161100869
Labeler code
16110
Product ID
16110-869_ae821f0c-ec53-4612-a505-e1aa9d73a158
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
azelaic acid
Dosage form
CREAM
Route
CUTANEOUS
Labeler
Almirall, LLC
Application
NDA020428
Marketing category
NDA
Marketing start
2018-09-24
Substance
AZELAIC ACID
Active strength
.2 g/g
Pharmacologic classes
Decreased Protein Synthesis [PE], Decreased Sebaceous Gland Activity [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020428-001AZELEXAZELAIC ACID20%CREAM / TOPICALRLD, RS1995-09-13

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-133f01610625f2…
2019-09-15 20:21 UTC2019-09N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020428-001AZELEX20%CREAM / TOPICALRLD, RS1995-09-13e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
AZELEX
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AZELAIC ACID.2 g/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
F2VW3D43YTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1041520Internal RxNorm lookup
1043753Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ebdfcaf7-b5d6-47e1-be87-ccaba4b97e75Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c6f86816-7da6-43ea-8c25-ac9758311cc5Product name120220118
6c6fc281-9445-2e9e-1c29-a09ddbc4299cProduct name220200213
252e11b6-1a9a-4283-a242-df2c129c496dProduct name320170717
2a856070-cbe7-4f85-be0f-09885ff91196Product name120150806

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16110-869-30AZELEX30 g in 1 TUBECREAM306
16110-869-30AZELEX1 in 1 CARTONCREAM16
16110-869-50AZELEX1 in 1 CARTONCREAM16
16110-869-50AZELEX50 g in 1 TUBECREAM506

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16110-869-30GM - Gram16110-8691f79b7be-4803-4ea8-9bf6-a3164f8ee62412020-02-13
16110-869-50GM - Gram16110-869f05d98bc-de89-4925-a90b-ffb67c87909b12020-02-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16110-869AZELEX (AZELAIC ACID) CREAM [ALMIRALL, LLC]6Current NDC, Legacy NDC, 4 package rows20240308_ebdfcaf7-b5d6-47e1-be87-ccaba4b97e75.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AZELEXAZELAIC ACIDAlmirall, LLCebdfcaf7-b5d6-47e1-be87-ccaba4b97e752024-03-04Warnings, Adverse reactionsExact identifier
application applno (NDA): 020428
application number: NDA020428
ndc (product): 16110-869

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1041520azelaic acid 20 % Topical CreamPSNebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1043753Azelex 20 % Topical CreamPSNebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1043753azelaic acid 200 MG/ML Topical Cream [Azelex]SBDebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1041520azelaic acid 200 MG/ML Topical CreamSCDebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1041520azelaic acid 20 % Topical CreamSYebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1043753Azelex 20 % Topical CreamSYebdfcaf7-b5d6-47e1-be87-ccaba4b97e756
1043753Azelex 200 MG/ML Topical CreamSYebdfcaf7-b5d6-47e1-be87-ccaba4b97e756

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
16110-869-30161100869301 TUBE in 1 CARTON (16110-869-30) / 30 g in 1 TUBE1 tube2019-07-120000-00-00NoNoCurrent
16110-869-50161100869501 TUBE in 1 CARTON (16110-869-50) / 50 g in 1 TUBE1 tube2019-07-120000-00-00NoNoCurrent