Eplerenone

Product NDC
16571-174
11-digit product format
165710174
Labeler code
16571
Product ID
16571-174_9fdff54f-c6fc-4215-a611-5051a7fbae84
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Eplerenone
Dosage form
TABLET
Route
ORAL
Labeler
Rising Pharma Holdings, Inc.
Application
ANDA214663
Marketing category
ANDA
Marketing start
2024-09-30
Substance
EPLERENONE
Active strength
50 mg/1
Pharmacologic classes
Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A214663-001EPLERENONEEPLERENONE25MGTABLET / ORALAB2022-03-23
A214663-002EPLERENONEEPLERENONE50MGTABLET / ORALAB2022-03-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A214663-001AB
A214663-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 60 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-232680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-235bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23d06236e962d9…
2024-10-29 15:01 UTC2024-10A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-2379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-231e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-238072bd15b7f6…
2024-05-31 18:47 UTC2024-05A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-235c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-235d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-235d02ea3f76ae…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-236a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-231c564ffb4f44…
2024-02-18 07:12 UTC2024-02A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214663-001EPLERENONE25MGTABLET / ORALAB2022-03-23a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214663-002EPLERENONE50MGTABLET / ORALAB2022-03-23a72a2bbeb626…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 60 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A214663-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A214663-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214663-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214663-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A214663-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A214663-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214663-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214663-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214663-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214663-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214663-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214663-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214663-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214663-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214663-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214663-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214663-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214663-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214663-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A214663-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214663-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214663-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214663-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214663-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214663-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214663-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214663-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A214663-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A214663-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A214663-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A214663-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A214663-002AB15d02ea3f76ae…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214663-001AB16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214663-002AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214663-001AB11c564ffb4f44…
2024-02-18 07:12 UTC2024-02A214663-002AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214663-001AB1ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A214663-002AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214663-001AB1a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214663-002AB1a72a2bbeb626…

Additional Listing Data#

Finished product
Yes
Brand name base
Eplerenone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPLERENONE50 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6995V82D0BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351256Internal RxNorm lookup
351257Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9b66a393-8af1-42bc-9673-89fe471147eeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6c046e2c-42d6-3179-f149-f207119f6ad5Product name620240530

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16571-174-03Eplerenone30 in 1 BOTTLETABLET302
16571-174-09Eplerenone90 in 1 BOTTLETABLET902

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16571-174-03EA - Each16571-17456b11b11-4db7-4586-9824-98cb00f3a3a812025-02-10
16571-174-09EA - Each16571-174c50c2158-ab6e-410a-8a8c-dcb99606a09d12025-02-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16571-174EPLERENONE TABLET [RISING PHARMA HOLDINGS, INC.]1Current NDC, 2 package rows20241001_9b66a393-8af1-42bc-9673-89fe471147ee.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EplerenoneEPLERENONERising Pharma Holdings, Inc.9b66a393-8af1-42bc-9673-89fe471147ee2025-06-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214663
application number: ANDA214663
ndc (product): 16571-174

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351256eplerenone 25 MG Oral TabletPSN9b66a393-8af1-42bc-9673-89fe471147ee2
351257eplerenone 50 MG Oral TabletPSN9b66a393-8af1-42bc-9673-89fe471147ee2
351256eplerenone 25 MG Oral TabletSCD9b66a393-8af1-42bc-9673-89fe471147ee2
351257eplerenone 50 MG Oral TabletSCD9b66a393-8af1-42bc-9673-89fe471147ee2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
16571-174-031657101740330 TABLET in 1 BOTTLE (16571-174-03) 30 tablet2024-09-30NoNoCurrent
16571-174-091657101740990 TABLET in 1 BOTTLE (16571-174-09) 90 tablet2024-09-30NoNoCurrent