Isosorbide dinitrate

Product NDC
16714-008
11-digit product format
167140008
Labeler code
16714
Product ID
16714-008_be0de7ff-f8d9-472f-a35c-252a2cf16954
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Isosorbide dinitrate
Dosage form
TABLET
Route
ORAL
Labeler
Northstar Rx LLC
Application
ANDA213057
Marketing category
ANDA
Marketing start
2020-05-01
Substance
ISOSORBIDE DINITRATE
Active strength
10 mg/1
Pharmacologic classes
Nitrate Vasodilator [EPC], Nitrates [CS], Vasodilation [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213057-001ISOSORBIDE DINITRATEISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-20
A213057-002ISOSORBIDE DINITRATEISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-20
A213057-003ISOSORBIDE DINITRATEISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-20
A213057-004ISOSORBIDE DINITRATEISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-20
A213057-005ISOSORBIDE DINITRATEISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 5 matching rows.

Application-product, TE code table
Application-productTE code
A213057-001AB
A213057-002AB
A213057-003AB
A213057-004AB
A213057-005AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 190 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-001ISOSORBIDE DINITRATE5MGTABLET / ORALAB2019-11-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-002ISOSORBIDE DINITRATE10MGTABLET / ORALAB2019-11-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-003ISOSORBIDE DINITRATE20MGTABLET / ORALAB2019-11-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-004ISOSORBIDE DINITRATE30MGTABLET / ORALAB2019-11-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-005ISOSORBIDE DINITRATE40MGTABLET / ORALAB2019-11-205bbf6a4d5a75…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 5 · 190 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A213057-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-004AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213057-005AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-004AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213057-005AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213057-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-004AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213057-005AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-004AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213057-005AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-004AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213057-005AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-004AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213057-005AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-004AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213057-005AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-004AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213057-005AB15bbf6a4d5a75…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Isosorbide dinitrateISOSORBIDE DINITRATENorthstar Rx LLC246c749d-aa28-44ce-8d42-984660afff2a2025-08-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213057
application number: ANDA213057
ndc (product): 16714-008
Isosorbide dinitrateISOSORBIDE DINITRATEBluePoint Laboratoriesf1d52e9a-8de1-61db-e053-2a95a90aae502024-09-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213057
application number: ANDA213057
Isosorbide dinitrateISOSORBIDE DINITRATEZydus Pharmaceuticals (USA) Inc.16818b32-ee5e-4e07-b848-31e892c4b98a2024-08-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213057
application number: ANDA213057
Isosorbide dinitrateISOSORBIDE DINITRATEZydus Lifesciences Limited5b0db8af-bcf9-458f-b752-420130cba4282023-11-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213057
application number: ANDA213057

Additional Listing Data#

Finished product
Yes
Brand name base
Isosorbide dinitrate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ISOSORBIDE DINITRATE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
IA7306519NInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197839Internal RxNorm lookup
206842Internal RxNorm lookup
314055Internal RxNorm lookup
381056Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
246c749d-aa28-44ce-8d42-984660afff2aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e9ed2ee5-d109-4795-bffe-c3b047717749Product name220250107
1ee44c84-1ad7-16b4-788d-a549f91b0f44Product name420230316
0dcc68a5-df0d-b1a6-ba71-3da99d94ffe9Product name120140508
b0c258c1-3fb1-4785-4031-5c4417fb7ecdProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16714-008-01Isosorbide dinitrate100 in 1 BOTTLETABLET1005

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16714-008-01EA - Each16714-008d7ce8df8-5df7-4ac4-b154-f3b52cab4b8512020-08-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16714-008ISOSORBIDE DINITRATE TABLET [NORTHSTAR RX LLC]3Current NDC, Legacy NDC, 1 package rows20240809_246c749d-aa28-44ce-8d42-984660afff2a.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
381056isosorbide dinitrate 10 MG Oral TabletPSN246c749d-aa28-44ce-8d42-984660afff2a5
206842isosorbide dinitrate 20 MG Oral TabletPSN246c749d-aa28-44ce-8d42-984660afff2a5
197839isosorbide dinitrate 30 MG Oral TabletPSN246c749d-aa28-44ce-8d42-984660afff2a5
314055isosorbide dinitrate 5 MG Oral TabletPSN246c749d-aa28-44ce-8d42-984660afff2a5
381056isosorbide dinitrate 10 MG Oral TabletSCD246c749d-aa28-44ce-8d42-984660afff2a5
206842isosorbide dinitrate 20 MG Oral TabletSCD246c749d-aa28-44ce-8d42-984660afff2a5
197839isosorbide dinitrate 30 MG Oral TabletSCD246c749d-aa28-44ce-8d42-984660afff2a5
314055isosorbide dinitrate 5 MG Oral TabletSCD246c749d-aa28-44ce-8d42-984660afff2a5
381056ISDN 10 MG Oral TabletSY246c749d-aa28-44ce-8d42-984660afff2a5
206842ISDN 20 MG Oral TabletSY246c749d-aa28-44ce-8d42-984660afff2a5
197839ISDN 30 MG Oral TabletSY246c749d-aa28-44ce-8d42-984660afff2a5
314055ISDN 5 MG Oral TabletSY246c749d-aa28-44ce-8d42-984660afff2a5

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
16714-008-0116714000801100 TABLET in 1 BOTTLE (16714-008-01) 100 tablet2020-05-010000-00-00NoNoCurrent