PEMETREXED

Product NDC
16729-244
Requested package NDC
16729-244-38
11-digit product format
167290244
Labeler code
16729
Product ID
16729-244_1d874430-c6ce-cff2-e063-6394a90a4a49
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Pemetrexed
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Accord Healthcare Inc.
Application
ANDA203485
Marketing category
ANDA
Marketing start
2022-05-25
Substance
PEMETREXED DISODIUM HEMIPENTAHYDRATE
Active strength
1 g/40mL
Pharmacologic classes
Folate Analog Metabolic Inhibitor [EPC], Folic Acid Metabolism Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203485-001PEMETREXED DISODIUMPEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25
A203485-002PEMETREXED DISODIUMPEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25
A203485-003PEMETREXED DISODIUMPEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A203485-001AP
A203485-002AP
A203485-003AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 87 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-002PEMETREXED DISODIUMEQ 500MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-003PEMETREXED DISODIUMEQ 1GM BASE/VIALPOWDER / INTRAVENOUSAP2022-05-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203485-001PEMETREXED DISODIUMEQ 100MG BASE/VIALPOWDER / INTRAVENOUSAP2022-05-258072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 87 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A203485-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203485-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203485-003AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203485-003AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203485-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203485-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203485-003AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203485-003AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203485-003AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203485-003AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203485-003AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203485-003AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203485-003AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203485-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203485-002AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203485-003AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-002AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203485-003AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-002AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203485-003AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-002AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203485-003AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203485-001AP18072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
PEMETREXED
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PEMETREXED DISODIUM HEMIPENTAHYDRATE1 g/40mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
F4GSH45R4CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1728072Internal RxNorm lookup
1728077Internal RxNorm lookup
2601728Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
dfd19e67-54cb-c062-e053-2995a90a294aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6b7ab8f1-bb38-4c30-8b8b-003c0fe639eaProduct name120250303
0976ea44-ea26-403d-a39d-71fffc6a3d33Product name420250225
f15e8921-7cd5-4c00-9cde-9fa0c9eaca68Product name120231013
0bb393b5-af67-4798-84a7-b797956b02a5Product name120230830
7ea5dc07-b4d4-439d-8145-a10a534148e7Product name120230320
a620f3f0-1e13-41d6-a838-d5407971d39eProduct name120230313
8766e415-735a-4d2c-b173-894ecced3fd9Product name120230308

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16729-244-38PEMETREXED1 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,14
16729-244-38PEMETREXED40 mL in 1 VIALINJECTION, POWDER, LYOPHILIZED,404

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16729-244-38EA - Each16729-244cc42d890-8355-4beb-8f3d-60e4ebffe9da12022-06-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16729-244PEMETREXED INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ACCORD HEALTHCARE INC.]4Current NDC, Legacy NDC, 2 package rows20240719_dfd19e67-54cb-c062-e053-2995a90a294a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PEMETREXEDPEMETREXEDAccord Healthcare Inc.dfd19e67-54cb-c062-e053-2995a90a294a2024-07-18Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203485
application number: ANDA203485
ndc (package): 16729-244-38
ndc (product): 16729-244
ndc11 (package): 16729024438

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2601728PEMEtrexed 1 GM InjectionPSNdfd19e67-54cb-c062-e053-2995a90a294a4
1728077PEMEtrexed 100 MG InjectionPSNdfd19e67-54cb-c062-e053-2995a90a294a4
1728072PEMEtrexed 500 MG InjectionPSNdfd19e67-54cb-c062-e053-2995a90a294a4
1728077pemetrexed 100 MG InjectionSCDdfd19e67-54cb-c062-e053-2995a90a294a4
2601728pemetrexed 1000 MG InjectionSCDdfd19e67-54cb-c062-e053-2995a90a294a4
1728072pemetrexed 500 MG InjectionSCDdfd19e67-54cb-c062-e053-2995a90a294a4
2601728pemetrexed (as disodium heptahydrate) 1 GM InjectionSYdfd19e67-54cb-c062-e053-2995a90a294a4
2601728pemetrexed (as disodium heptahydrate) 1000 MG InjectionSYdfd19e67-54cb-c062-e053-2995a90a294a4
1728077pemetrexed 100 MG InjectionSYdfd19e67-54cb-c062-e053-2995a90a294a4
1728072pemetrexed 500 MG InjectionSYdfd19e67-54cb-c062-e053-2995a90a294a4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
16729-244-38167290244381 VIAL in 1 CARTON (16729-244-38) / 40 mL in 1 VIAL1 vial2022-05-250000-00-00NoNoCurrent