3M SoluPrep S

Product NDC
17518-083
11-digit product format
175180083
Labeler code
17518
Product ID
17518-083_dc639f31-0e60-42dc-ab1c-e1f114c28a7a
Type
HUMAN OTC DRUG
Nonproprietary name
Chlorhexidine Gluconate and Isopropyl Alcohol
Dosage form
SOLUTION
Route
TOPICAL
Labeler
Solventum US LLC
Application
NDA208288
Marketing category
NDA
Marketing start
2023-01-23
Substance
CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL
Active strength
20; .7 mg/mL; mL/mL
Pharmacologic classes
Decreased Cell Wall Integrity [PE]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208288-001SOLUPREP SCHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL2%;70%SOLUTION / TOPICALRLD, RS2018-08-08

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 1 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N208288-001M-2922026-01-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-0831067a03dcf5…
2025-08-23 18:47 UTC2025-08N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-086a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-0803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-082680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-085bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-0879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-081e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-088072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-085c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-085d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-084b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-0874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-0887673890dc5c…
2021-03-12 10:30 UTC2021-03N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-085aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-088869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-083f01610625f2…
2019-09-15 20:21 UTC2019-09N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-086a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-081c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-089b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-083f0d92c62455…
2023-05-13 08:27 UTC2023-05N208288-001SOLUPREP S2%;70%SOLUTION / TOPICALRLD, RS2018-08-08053a50430f4f…
2023-01-26 05:58 UTC2023-01N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-083bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-083a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208288-001SOLUPREP2%;70%SOLUTION / TOPICALRLD, RS2018-08-08e64feba35796…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208288-00186239352029-07-26U-1022Drug product2018-09-065c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208288-00186239352029-07-26U-1022Drug product2018-09-065d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208288-00186239352029-07-26U-1022Drug product2018-09-064b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208288-00186239352029-07-26U-1022Drug product2018-09-0674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208288-00186239352029-07-26U-1022Drug product2018-09-06bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208288-00186239352029-07-26U-1022Drug product2018-09-06782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208288-00186239352029-07-26U-1022Drug product2018-09-0687673890dc5c…
2021-03-12 10:30 UTC2021-03N208288-00186239352029-07-26U-1022Drug product2018-09-065aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208288-00186239352029-07-26U-1022Drug product2018-09-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208288-00186239352029-07-26U-1022Drug product2018-09-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208288-00186239352029-07-26U-1022Drug product2018-09-063f01610625f2…
2019-09-15 20:21 UTC2019-09N208288-00186239352029-07-26U-1022Drug product2018-09-06b00525d2431f…
2019-07-19 19:46 UTC2019-07N208288-00186239352029-07-26U-1022Drug product2018-09-06ea99ee380514…
2023-01-26 05:58 UTC2023-01N208288-00186239352029-07-26U-1022Drug product2018-09-063bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208288-00186239352029-07-26U-1022Drug product2018-09-063a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208288-00186239352029-07-26U-1022Drug product2018-09-06f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208288-00186239352029-07-26U-1022Drug product2018-09-06e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N208288-00186239352029-07-26U-1022Drug product2018-09-06cb3db0bc1861…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N208288-001M-2922026-01-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208288-001M-2922026-01-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208288-001M-2922026-01-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N208288-001M-2922026-01-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208288-001M-2922026-01-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208288-001M-2922026-01-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208288-001M-2922026-01-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208288-001M-2922026-01-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208288-001M-2922026-01-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208288-001M-2922026-01-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208288-001M-2922026-01-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208288-001M-2922026-01-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208288-001M-2922026-01-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208288-001M-2922026-01-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208288-001M-2922026-01-208072bd15b7f6…
2019-12-13 00:20 UTC2019-12N208288-001NP2021-08-0874a2ff9319b5…
2021-12-28 21:50 UTC2021-12N208288-001NP2021-08-08782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208288-001NP2021-08-0887673890dc5c…
2021-03-12 10:30 UTC2021-03N208288-001NP2021-08-085aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208288-001NP2021-08-088869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208288-001NP2021-08-08c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208288-001NP2021-08-083f01610625f2…
2019-09-15 20:21 UTC2019-09N208288-001NP2021-08-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N208288-001NP2021-08-08ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208288-001M-2922026-01-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208288-001M-2922026-01-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208288-001M-2922026-01-20ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208288-001M-2922026-01-20a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208288-001M-2922026-01-209b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208288-001M-2922026-01-20a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208288-001M-2922026-01-203f0d92c62455…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N208288-001M-2922026-01-20a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
3M SoluPrep S
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CHLORHEXIDINE GLUCONATE20 mg/mL
ISOPROPYL ALCOHOL.7 mL/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
MOR84MUD8EInternal UNII lookup
ND2M416302Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
858726Internal RxNorm lookup
2629724Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
084aa305-5863-441a-a94d-36bc1b05195aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6c13b22c-b3ba-4127-b768-0132dd5ab0d1Product name120230829
bb6d6c68-649d-4e6d-a1f6-603d969c8f68Product name120160303

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
17518-083-023M SoluPrep S10.5 mL in 1 APPLICATORSOLUTION10.55
17518-083-023M SoluPrep S1 in 1 POUCHSOLUTION15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
17518-0833M SOLUPREP S (CHLORHEXIDINE GLUCONATE AND ISOPROPYL ALCOHOL) SOLUTION [SOLVENTUM US LLC]4Current NDC, 2 package rows20240808_084aa305-5863-441a-a94d-36bc1b05195a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
3M SoluPrep SCHLORHEXIDINE GLUCONATE AND ISOPROPYL ALCOHOLSolventum US LLC084aa305-5863-441a-a94d-36bc1b05195a2026-04-23WarningsExact identifier
application applno (NDA): 208288
application number: NDA208288
ndc (product): 17518-083

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
858726chlorhexidine gluconate 2 % / isopropyl alcohol 70 % Topical SolutionPSN084aa305-5863-441a-a94d-36bc1b05195a5
2629724SoluPrep 2 % / 70 % Topical SolutionPSN084aa305-5863-441a-a94d-36bc1b05195a5
2629724chlorhexidine gluconate 20 MG/ML / isopropyl alcohol 0.7 ML/ML Topical Solution [Soluprep]SBD084aa305-5863-441a-a94d-36bc1b05195a5
858726chlorhexidine gluconate 20 MG/ML / isopropyl alcohol 0.7 ML/ML Topical SolutionSCD084aa305-5863-441a-a94d-36bc1b05195a5
858726chlorhexidine gluconate 2 % / isopropyl alcohol 70 % Topical SolutionSY084aa305-5863-441a-a94d-36bc1b05195a5
2629724SoluPrep (chlorhexidine gluconate 2 % / isopropyl alcohol 70 % ) Topical SolutionSY084aa305-5863-441a-a94d-36bc1b05195a5

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
17518-083-02175180083021 APPLICATOR in 1 POUCH (17518-083-02) / 10.5 mL in 1 APPLICATOR1 applicator2023-01-23NoNoCurrent