promethazine hydrochloride

Product NDC
17856-0059
11-digit product format
178560059
Labeler code
17856
Product ID
17856-0059_45b43457-b9cd-09a2-e063-6294a90a698d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
promethazine hydrochloride
Dosage form
SYRUP
Route
ORAL
Labeler
ATLANTIC BIOLOGICALS CORP
Application
ANDA091675
Marketing category
ANDA
Marketing start
2012-06-08
Substance
PROMETHAZINE HYDROCHLORIDE
Active strength
6.25 mg/5mL
Pharmacologic classes
Phenothiazine [EPC], Phenothiazines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 14 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCCodeStatusSnapshotSource SHA-256
2025-04-01 02:39 UTC · source 2025-03-31excluded productproductIInactivated by FDA2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage17856-0059-1IInactivated by FDA2ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproductIInactivated by FDAa1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage17856-0059-1IInactivated by FDAa1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductIInactivated by FDAcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage17856-0059-1IInactivated by FDAcfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductIInactivated by FDAcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage17856-0059-1IInactivated by FDAcdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproductUExcluded because listing certification expired302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage17856-0059-1UExcluded because listing certification expired302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproductUExcluded because listing certification expireded331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage17856-0059-1UExcluded because listing certification expireded331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproductUExcluded because listing certification expired0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage17856-0059-1UExcluded because listing certification expired0efc9e666f02…f202fb6c5f17…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A091675-001PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A091675-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-2887673890dc5c…
2021-03-12 10:30 UTC2021-03A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-283f01610625f2…
2019-09-15 20:21 UTC2019-09A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28b00525d2431f…
2019-07-19 19:46 UTC2019-07A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-283f0d92c62455…
2023-05-13 08:27 UTC2023-05A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28053a50430f4f…
2023-01-26 05:58 UTC2023-01A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091675-001PROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAA2012-06-28e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A091675-001AA1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A091675-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091675-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091675-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091675-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091675-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091675-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091675-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091675-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091675-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091675-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091675-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091675-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091675-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091675-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091675-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091675-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091675-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091675-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091675-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091675-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091675-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A091675-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091675-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091675-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091675-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A091675-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A091675-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091675-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091675-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091675-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091675-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091675-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091675-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091675-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A091675-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A091675-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091675-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091675-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091675-001AA1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
promethazine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROMETHAZINE HYDROCHLORIDE6.25 mg/5mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
R61ZEH7I1IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
992432Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
69934bbb-922c-4752-b253-f2f07340de8dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3036445d-7d13-4411-a100-f2ac5ab8a276Product name120240110
2e7222fb-e3f1-febd-962f-ddbb495d6b5fProduct name220220126
09d8330d-4fec-be98-3a66-f985140646b2Product name220210513
c5cd4727-ac49-4409-82b1-5bd8006c3ec7Product name120171122
4f881de7-085a-407e-abc2-faa3c0127432Product name120170811
e0b6c8be-f2bd-9f86-a9fc-3ed56ffaa814Product name320150910
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
76633df9-0d59-4b88-03ed-21dee1b966f8Product name120140508
d51697af-7f97-0559-95d1-fe94f3f031d5Product name120140508
e949165d-714d-e548-2b76-0cb5def16f30Product name120140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
17856-0059-12025-03-28C16284748780-12cef2736-b2d5-d83d-e063-dadaa90ab31fPromethazine HCL Syrup
17856-0059-12025-01-30C16284748780-12cef2736-b2d5-d83d-e063-dadaa90ab31fPromethazine HCL Syrup

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
17856-0059-1promethazine hydrochloride72 in 1 BOX, UNIT-DOSESYRUP724
17856-0059-1promethazine hydrochloride5 mL in 1 CUP, UNIT-DOSESYRUP54

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
17856-0059-1ML - Milliliter17856-0059dc11f412-17e9-45f3-b2e3-d79fdb06b69e12025-06-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
17856-0059PROMETHAZINE HYDROCHLORIDE SYRUP [ATLANTIC BIOLOGICALS CORP]3Current NDC, 2 package rows20250525_69934bbb-922c-4752-b253-f2f07340de8d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
promethazine hydrochloridePROMETHAZINE HYDROCHLORIDECranbury Pharmaceuticals, LLCd32ea9db-11d4-400d-b7ef-dd0ec01b796d2025-12-12Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091675
application number: ANDA091675
promethazine hydrochloridePROMETHAZINE HYDROCHLORIDEATLANTIC BIOLOGICALS CORP69934bbb-922c-4752-b253-f2f07340de8d2025-12-11Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091675
application number: ANDA091675
ndc (product): 17856-0059
promethazine hydrochloridePROMETHAZINE HYDROCHLORIDEA-S Medication Solutionsc0a68671-407b-4840-9662-04f168cff1cb2023-09-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091675
application number: ANDA091675

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
992432promethazine HCl 6.25 MG in 5 mL Oral SolutionPSN69934bbb-922c-4752-b253-f2f07340de8d4
992432promethazine hydrochloride 1.25 MG/ML Oral SolutionSCD69934bbb-922c-4752-b253-f2f07340de8d4
992432promethazine HCl 6.25 MG per 5 ML Oral SyrupSY69934bbb-922c-4752-b253-f2f07340de8d4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
17856-0059-11785600590172 CUP, UNIT-DOSE in 1 BOX, UNIT-DOSE (17856-0059-1) / 5 mL in 1 CUP, UNIT-DOSE2023-11-13NoNoCurrent