LACTULOSE

Product NDC
17856-0874
11-digit product format
178560874
Labeler code
17856
Product ID
17856-0874_3fb6eaf7-8029-7a5c-e063-6294a90a6889
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lactulose
Dosage form
SOLUTION
Route
ORAL
Labeler
Atlantic Biologicals Corp.
Application
ANDA074623
Marketing category
ANDA
Marketing start
2019-12-03
Substance
LACTULOSE
Active strength
10 g/15mL
Pharmacologic classes
Acidifying Activity [MoA], Osmotic Activity [MoA], Osmotic Laxative [EPC], Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074623-001LACTULOSELACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A074623-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAARS1996-07-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-3087673890dc5c…
2021-03-12 10:30 UTC2021-03A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-303f01610625f2…
2019-09-15 20:21 UTC2019-09A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30b00525d2431f…
2019-07-19 19:46 UTC2019-07A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-303f0d92c62455…
2023-05-13 08:27 UTC2023-05A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30053a50430f4f…
2023-01-26 05:58 UTC2023-01A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074623-001LACTULOSE10GM/15MLSOLUTION / ORALAA1996-07-30cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A074623-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074623-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074623-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074623-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074623-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074623-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074623-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074623-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074623-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074623-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074623-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074623-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074623-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074623-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074623-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074623-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074623-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074623-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074623-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074623-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074623-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A074623-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074623-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074623-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074623-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A074623-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A074623-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074623-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074623-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074623-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074623-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074623-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074623-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074623-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A074623-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A074623-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074623-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074623-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074623-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074623-001AA1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
LACTULOSE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LACTULOSE10 g/15mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9U7D5QH5AEInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
391937Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3fb6e908-893c-5a57-e063-6294a90a1bfcAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
13620a32-e3b4-4aad-8280-283dce30ddffProduct name120260105
27883b46-af31-44b0-b4ce-e6b4f6d825a7Product name420250812
c1a80c95-0e51-52a0-75fa-75808f51ded8Product name220150421

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
17856-0874-3LACTULOSE30 mL in 1 CUP, UNIT-DOSESOLUTION301
17856-0874-3LACTULOSE50 in 1 CASESOLUTION501

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
17856-0874-3ML - Milliliter17856-08746835883f-8bcc-43f0-8237-dbfc9b6a7f1612026-02-05

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LACTULOSELACTULOSECardinal Health 107, LLC3cf3ff7c-67e7-42a9-8ebb-bd6c53937dd72026-05-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074623
application number: ANDA074623
LACTULOSELACTULOSEAtlantic Biologicals Corp.3fb6e908-893c-5a57-e063-6294a90a1bfc2025-09-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074623
application number: ANDA074623
ndc (product): 17856-0874
LACTULOSELACTULOSEPAI Holdings, LLC dba PAI Pharma0f19e4ed-c90a-4330-a7fa-bf911aa98f092025-09-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074623
application number: ANDA074623
LACTULOSELACTULOSEPAI Holdings, LLC dba PAI Pharmacbf0497c-9c8d-4dfa-bebd-64c5894684012025-09-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074623
application number: ANDA074623
LACTULOSELACTULOSEProficient Rx LP6bbabdc6-f6a8-4f67-a448-e452d1928deb2024-06-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074623
application number: ANDA074623

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
391937lactulose 10 GM in 15 mL Oral SolutionPSN3fb6e908-893c-5a57-e063-6294a90a1bfc1
391937lactulose 667 MG/ML Oral SolutionSCD3fb6e908-893c-5a57-e063-6294a90a1bfc1
391937lactulose 10 GM per 15 ML Oral SolutionSY3fb6e908-893c-5a57-e063-6294a90a1bfc1
391937lactulose 20 GM per 30 ML Oral SolutionSY3fb6e908-893c-5a57-e063-6294a90a1bfc1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
17856-0874-31785608740350 CUP, UNIT-DOSE in 1 CASE (17856-0874-3) / 30 mL in 1 CUP, UNIT-DOSE2025-09-26NoNoCurrent