PROMETHAZINE HYDROCHLORIDE

Product NDC
17856-4023
11-digit product format
178564023
Labeler code
17856
Product ID
17856-4023_4f99bbe0-279d-da57-e063-6294a90ab362
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
promethazine hydrochloride
Dosage form
SYRUP
Route
ORAL
Labeler
Atlantic Biologicals Corp.
Application
ANDA087953
Marketing category
ANDA
Marketing start
2025-04-07
Substance
PROMETHAZINE HYDROCHLORIDE
Active strength
6.25 mg/5mL
Pharmacologic classes
Phenothiazine [EPC], Phenothiazines [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A087953-001PROMETHAZINE PLAINPROMETHAZINE HYDROCHLORIDE6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A087953-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-158072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-155c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-155d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-154b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-1574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-1587673890dc5c…
2021-03-12 10:30 UTC2021-03A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-155aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-158869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-15c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-153f01610625f2…
2019-09-15 20:21 UTC2019-09A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-15b00525d2431f…
2019-07-19 19:46 UTC2019-07A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARS1982-11-15ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-156a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-151c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-159b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-153f0d92c62455…
2023-05-13 08:27 UTC2023-05A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15053a50430f4f…
2023-01-26 05:58 UTC2023-01A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-153bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-153a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087953-001PROMETHAZINE PLAIN6.25MG/5MLSYRUP / ORALAARLD, RS1982-11-15e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A087953-001AA1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A087953-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087953-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A087953-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087953-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087953-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087953-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087953-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087953-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087953-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087953-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087953-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087953-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087953-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087953-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087953-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087953-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087953-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087953-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087953-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087953-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087953-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A087953-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087953-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087953-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087953-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A087953-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A087953-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087953-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087953-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087953-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087953-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087953-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087953-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087953-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A087953-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A087953-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087953-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087953-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087953-001AA1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
PROMETHAZINE HYDROCHLORIDE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROMETHAZINE HYDROCHLORIDE6.25 mg/5mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
R61ZEH7I1IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
992432Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4f99bbd5-02f7-2fed-e063-6394a90a6355Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3036445d-7d13-4411-a100-f2ac5ab8a276Product name120240110
2e7222fb-e3f1-febd-962f-ddbb495d6b5fProduct name220220126
09d8330d-4fec-be98-3a66-f985140646b2Product name220210513
c5cd4727-ac49-4409-82b1-5bd8006c3ec7Product name120171122
4f881de7-085a-407e-abc2-faa3c0127432Product name120170811
e0b6c8be-f2bd-9f86-a9fc-3ed56ffaa814Product name320150910
76633df9-0d59-4b88-03ed-21dee1b966f8Product name120140508
d51697af-7f97-0559-95d1-fe94f3f031d5Product name120140508
e949165d-714d-e548-2b76-0cb5def16f30Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
17856-4023-1PROMETHAZINE HYDROCHLORIDE72 in 1 CASESYRUP721
17856-4023-1PROMETHAZINE HYDROCHLORIDE5 mL in 1 CUP, UNIT-DOSESYRUP51

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDEAtlantic Biologicals Corp.4f99bbd5-02f7-2fed-e063-6394a90a63552026-04-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087953
application number: ANDA087953
ndc (product): 17856-4023
PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDEXttrium Laboratories, Inc.302bfea2-d403-d315-e063-6294a90a37dd2025-04-07Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087953
application number: ANDA087953

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
992432promethazine HCl 6.25 MG in 5 mL Oral SolutionPSN4f99bbd5-02f7-2fed-e063-6394a90a63551
992432promethazine hydrochloride 1.25 MG/ML Oral SolutionSCD4f99bbd5-02f7-2fed-e063-6394a90a63551
992432promethazine HCl 6.25 MG per 5 ML Oral SyrupSY4f99bbd5-02f7-2fed-e063-6394a90a63551

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
17856-4023-11785640230172 CUP, UNIT-DOSE in 1 CASE (17856-4023-1) / 5 mL in 1 CUP, UNIT-DOSE2026-04-20NoNoCurrent