Signature Care Pain Relief

Product NDC: 21130-111
11-digit product format: 211300111
Labeler code: 21130
Product ID: 21130-111_e36b10d6-75a1-413e-bd04-fca97d3376b9
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen
Dosage form: TABLET
Route: ORAL
Labeler: Safeway
Application: part343
Marketing category: OTC MONOGRAPH NOT FINAL
Marketing start: 2015-09-01
Marketing end: 0000-00-00
Substance: ACETAMINOPHEN
Active strength: 500 mg/1
NDC exclude flag: No
Listing certified through: 2020-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 6 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	21130-111		D	Discontinued by firm	2026-11-12
excluded package	package	21130-111	21130-111-62	D	Discontinued by firm	2026-11-12
excluded package	package	21130-111	21130-111-71	D	Discontinued by firm	2026-11-12
excluded package	package	21130-111	21130-111-78	D	Discontinued by firm	2026-11-12
excluded package	package	21130-111	21130-111-85	D	Discontinued by firm	2026-11-12
excluded package	package	21130-111	21130-111-90	D	Discontinued by firm	2026-11-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 8 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	21130-111-90	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	21130-111-62	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	21130-111-90	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	21130-111-62	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	21130-111-90	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	21130-111-90	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	21130-111-90	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	21130-111-90	`cdf11ea48f46…`	`ba0047e9e063…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
21130-111-62	Signature Care Pain Relief	1 in 1 CARTON	TABLET	1	5
21130-111-62	Signature Care Pain Relief	24 in 1 BOTTLE	TABLET	24	5
21130-111-71	Signature Care Pain Relief	50 in 1 BOTTLE	TABLET	50	5
21130-111-71	Signature Care Pain Relief	1 in 1 CARTON	TABLET	1	5
21130-111-78	Signature Care Pain Relief	100 in 1 BOTTLE	TABLET	100	5
21130-111-78	Signature Care Pain Relief	1 in 1 CARTON	TABLET	1	5
21130-111-85	Signature Care Pain Relief	1 in 1 CARTON	TABLET	1	5
21130-111-85	Signature Care Pain Relief	250 in 1 BOTTLE	TABLET	250	5
21130-111-90	Signature Care Pain Relief	500 in 1 BOTTLE	TABLET	500	5

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
ACETAMINOPHEN	ACTIVE INGREDIENT	362O9ITL9D	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
ACETAMINOPHEN	ACTIVE MOIETY	362O9ITL9D	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
CARNAUBA WAX	INACTIVE INGREDIENT	R12CBM0EIZ	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
CROSCARMELLOSE SODIUM	INACTIVE INGREDIENT	M28OL1HH48	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
POLYETHYLENE GLYCOLS	INACTIVE INGREDIENT	3WJQ0SDW1A	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
POVIDONES	INACTIVE INGREDIENT	FZ989GH94E	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
21130-111	SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]	5	Legacy NDC, 9 package rows	20240924_917bcd06-6dc6-42b3-80b4-c6746b347261.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198440	acetaminophen 500 MG Oral Tablet	PSN	917bcd06-6dc6-42b3-80b4-c6746b347261	5
198440	acetaminophen 500 MG Oral Tablet	SCD	917bcd06-6dc6-42b3-80b4-c6746b347261	5
198440	APAP 500 MG Oral Tablet	SY	917bcd06-6dc6-42b3-80b4-c6746b347261	5

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
21130-111-62	21130011162	1 BOTTLE in 1 CARTON (21130-111-62) > 24 TABLET in 1 BOTTLE	1 bottle	2015-09-01	0000-00-00	No	No	Current
21130-111-71	21130011171	1 BOTTLE in 1 CARTON (21130-111-71) > 50 TABLET in 1 BOTTLE	1 bottle	2015-09-01	0000-00-00	No	No	Current
21130-111-78	21130011178	1 BOTTLE in 1 CARTON (21130-111-78) > 100 TABLET in 1 BOTTLE	1 bottle	2015-09-01	0000-00-00	No	No	Current
21130-111-85	21130011185	1 BOTTLE in 1 CARTON (21130-111-85) > 250 TABLET in 1 BOTTLE	1 bottle	2015-09-01	0000-00-00	No	No	Current
21130-111-90	21130011190	500 TABLET in 1 BOTTLE (21130-111-90)	500 tablet	2015-09-01	0000-00-00	No	No	Current