FDA.reportPublic FDA data

Signature Care Pain Relief

Product NDC
21130-111
11-digit product format
211300111
Labeler code
21130
Product ID
21130-111_c77c6d49-4bd8-4359-872c-4cc13aecb583
Type
HUMAN OTC DRUG
Nonproprietary name
Acetaminophen
Dosage form
TABLET
Route
ORAL
Labeler
Safeway
Application
M013
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2015-09-01
Substance
ACETAMINOPHEN
Active strength
500 mg/1
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage21130-11121130-111-62DDiscontinued by firm2026-10-16
excluded packagepackage21130-11121130-111-90DDiscontinued by firm2026-10-16

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 8 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source datePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-0521130-111-90d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-0521130-111-62d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-2621130-111-90f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-2621130-111-62f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-3121130-111-902ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-2821130-111-90a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-2121130-111-90cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-1021130-111-90cdf11ea48f46…ba0047e9e063…

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product
Yes
Brand name base
Signature Care Pain Relief
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ACETAMINOPHEN500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
362O9ITL9DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
198440Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
917bcd06-6dc6-42b3-80b4-c6746b347261Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
21130-111-62Signature Care Pain Relief1 in 1 CARTONTABLET15
21130-111-62Signature Care Pain Relief24 in 1 BOTTLETABLET245
21130-111-71Signature Care Pain Relief50 in 1 BOTTLETABLET505
21130-111-71Signature Care Pain Relief1 in 1 CARTONTABLET15
21130-111-78Signature Care Pain Relief100 in 1 BOTTLETABLET1005
21130-111-78Signature Care Pain Relief1 in 1 CARTONTABLET15
21130-111-85Signature Care Pain Relief1 in 1 CARTONTABLET15
21130-111-85Signature Care Pain Relief250 in 1 BOTTLETABLET2505
21130-111-90Signature Care Pain Relief500 in 1 BOTTLETABLET5005

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ACETAMINOPHENACTIVE INGREDIENT362O9ITL9DSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
ACETAMINOPHENACTIVE MOIETY362O9ITL9DSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
CARNAUBA WAXINACTIVE INGREDIENTR12CBM0EIZSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
CROSCARMELLOSE SODIUMINACTIVE INGREDIENTM28OL1HH48SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1ASIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
POVIDONESINACTIVE INGREDIENTFZ989GH94ESIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1
STEARIC ACIDINACTIVE INGREDIENT4ELV7Z65APSIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
21130-111SIGNATURE CARE PAIN RELIEF (ACETAMINOPHEN) TABLET [SAFEWAY]5Current NDC, Legacy NDC, 9 package rows20240924_917bcd06-6dc6-42b3-80b4-c6746b347261.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 42 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Childrens AcetaminophenACETAMINOPHENBryant Ranch Prepack190bb2dc-92b4-4b59-a47f-a0251df8261c2025-07-29WarningsExact identifier
application number: M013
Extra Strength NiteTime Pain ReliefACETAMINOPHEN 500 MG,DIPHENHYDRAMINE HYDROCHLORIDE 25 MG TABLETWALGREENSc25c75c7-157f-1c0d-e053-2995a90a2e3c2025-07-25WarningsExact identifier
application number: M013
Pain Reliever PMACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDEWalmart Inc.21ab3d58-bb0e-3e51-e063-6294a90ad4152025-07-25WarningsExact identifier
application number: M013
Childrens TYLENOLACETAMINOPHENKenvue Brands LLC3a935584-6045-0a58-e063-6394a90a40c42025-07-23WarningsExact identifier
application number: M013
DR. SANA PAIN AND FEVER FOR ChildrenACETAMINOPHENGADAL Laboratories, Inc8a22a5ba-8623-4cca-8723-52b4954034612025-07-23WarningsExact identifier
application number: M013
DuralginaACETAMINOPHENMenper Distributors Inc.bb31f66c-80a9-4bdb-983b-cef5d21de5ff2025-07-22WarningsExact identifier
application number: M013
GesteiraACETAMINOPHENMenper Distributors, Inc.5a907289-564c-491b-98d5-d7f43eaaa1b22025-07-22WarningsExact identifier
application number: M013
Extra strength Acetaminophen PMACETAMINOPHEN 500MG/ DIPHENHYDRAMINE HCL 25MGTIME CAP LABS INC010c5c98-fc67-a9c3-e063-6394a90aa6402025-07-21WarningsExact identifier
application number: M013
childrens pain and feverACETAMINOPHENMeijer Distribution Inc44d50d79-6e47-429f-8cbe-6fcac46677322025-07-18WarningsExact identifier
application number: M013
ADWE Childrens Pain FeverACETAMINOPHENRARITAN PHARMACEUTICALS INC79a3232f-0211-4c8a-acee-4f87e06ffc262025-07-17WarningsExact identifier
application number: M013
Pain RelieverACETAMINOPHENWalmart Inc.24d191ca-a0c4-e1a8-e063-6394a90a7a2a2025-07-16WarningsExact identifier
application number: M013
EXTRA STRENGTH HEADACHE RELIEFACETAMINOPHEN ASPIRIN CAFFEINEWAL-MART STORES INCd97073cd-b5d7-8c09-e053-2a95a90a89382025-07-16WarningsExact identifier
application number: M013
Pain ReliefACETAMINOPHENBETTER LIVING BRANDS LLC.f3005d0c-424e-0ab3-e053-2995a90a1c102025-07-16WarningsExact identifier
application number: M013
Pain ReliefACETAMINOPHENDemoulas Super Markets, Inc397fa6e1-37b2-8f51-e063-6394a90a7b942025-07-16WarningsExact identifier
application number: M013
Pain ReliefACETAMINOPHENDemoulas Super Markets, Inc39800c27-f39f-cd60-e063-6394a90acd552025-07-16WarningsExact identifier
application number: M013
Pain ReliefACETAMINOPHENDemoulas Super Markets, Inc397f2b63-733e-5b44-e063-6394a90a97182025-07-16WarningsExact identifier
application number: M013
EXTRA STRENGTH PAIN RELIEFACETAMINOPHEN, ASPIRIN, CAFFEINEBETTER LIVING BRANDS, LLCeb6026d5-d88a-f6b3-e053-2a95a90a5b202025-07-15WarningsExact identifier
application number: M013
Pain Relief PMACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDESafewayf9597abc-3f01-4b94-8078-228e0b74677e2025-07-15WarningsExact identifier
application number: M013
Berkley and Jensen Pain ReliefACETAMINOPHENBJWCd3ee3341-93b8-487c-921e-2892d213efbb2025-07-15WarningsExact identifier
application number: M013
Headache Relief Extra StrengthACETAMINOPHEN, ASPIRIN, CAFFEINECVS Pharmacy9e459853-5951-4ae7-88a6-85b502e9dd412025-07-14WarningsExact identifier
application number: M013

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
198440acetaminophen 500 MG Oral TabletPSN917bcd06-6dc6-42b3-80b4-c6746b3472615
198440acetaminophen 500 MG Oral TabletSCD917bcd06-6dc6-42b3-80b4-c6746b3472615
198440APAP 500 MG Oral TabletSY917bcd06-6dc6-42b3-80b4-c6746b3472615

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
21130-111-62211300111621 BOTTLE in 1 CARTON (21130-111-62) > 24 TABLET in 1 BOTTLE1 bottle2015-09-010000-00-00NoNoCurrent
21130-111-71211300111711 BOTTLE in 1 CARTON (21130-111-71) / 50 TABLET in 1 BOTTLE1 bottle2015-09-010000-00-00NoNoCurrent
21130-111-78211300111781 BOTTLE in 1 CARTON (21130-111-78) / 100 TABLET in 1 BOTTLE1 bottle2015-09-010000-00-00NoNoCurrent
21130-111-85211300111851 BOTTLE in 1 CARTON (21130-111-85) / 250 TABLET in 1 BOTTLE1 bottle2015-09-010000-00-00NoNoCurrent
21130-111-9021130011190500 TABLET in 1 BOTTLE (21130-111-90) 500 tablet2015-09-010000-00-00NoNoCurrent