Home NDC 21130-180 signature care naproxen sodium
Product NDC 21130-180
11-digit product format 211300180
Labeler code 21130
Product ID 21130-180_347809fc-ce5e-49ff-b4e5-a36aa9eb6a72
Type HUMAN OTC DRUG
Nonproprietary name Naproxen Sodium
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Safeway
Application ANDA074661
Marketing category ANDA
Marketing start 2018-04-03
Marketing end 2027-02-28
Substance NAPROXEN SODIUM
Active strength 220 mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag No
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date A074661-001 NAPROXEN SODIUM NAPROXEN SODIUM 220MG TABLET / ORAL 1997-01-13
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-08-01 22:54:32 2026-06 A074661-001 NAPROXEN SODIUM 220MG TABLET / ORAL 1997-01-13 a50c72e98297…
openFDA label cross-check# Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.
Matched openFDA labels page 1 of 3 · 56 matching rows.
Additional Listing Data#
Finished product Yes
Brand name base signature care naproxen sodium Active Ingredients# Ingredient, Strength table Ingredient Strength NAPROXEN SODIUM 220 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 9TN87S3A3C Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 849574 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 21130-180-62 signature care naproxen sodium 1 in 1 CARTON TABLET, FILM COATED 1 6 21130-180-62 signature care naproxen sodium 24 in 1 BOTTLE TABLET, FILM COATED 24 6 21130-180-71 signature care naproxen sodium 1 in 1 CARTON TABLET, FILM COATED 1 6 21130-180-71 signature care naproxen sodium 50 in 1 BOTTLE TABLET, FILM COATED 50 6 21130-180-75 signature care naproxen sodium 90 in 1 BOTTLE TABLET, FILM COATED 90 6 21130-180-75 signature care naproxen sodium 1 in 1 CARTON TABLET, FILM COATED 1 6 21130-180-78 signature care naproxen sodium 100 in 1 BOTTLE TABLET, FILM COATED 100 6 21130-180-78 signature care naproxen sodium 1 in 1 CARTON TABLET, FILM COATED 1 6 21130-180-79 signature care naproxen sodium 400 in 1 BOTTLE TABLET, FILM COATED 400 6
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 21130-180 SIGNATURE CARE NAPROXEN SODIUM (NAPROXEN SODIUM) TABLET, FILM COATED [SAFEWAY] 5 Current NDC, Legacy NDC, 9 package rows 20250308_85f78e63-98aa-4cf3-887d-0ac535184f97.zip
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 21130-180-62 21130018062 1 BOTTLE in 1 CARTON (21130-180-62) > 24 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2018-04-03 0000-00-00 No No Current 21130-180-71 21130018071 1 BOTTLE in 1 CARTON (21130-180-71) > 50 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2021-11-23 0000-00-00 No No Current 21130-180-75 21130018075 1 BOTTLE in 1 CARTON (21130-180-75) > 90 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2022-04-07 0000-00-00 No No Current 21130-180-78 21130018078 1 BOTTLE in 1 CARTON (21130-180-78) > 100 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2021-11-23 0000-00-00 No No Current 21130-180-79 21130018079 400 TABLET, FILM COATED in 1 BOTTLE (21130-180-79) 2021-11-23 2027-02-28 No No Current