Mesalamine

Product NDC
21922-045
11-digit product format
219220045
Labeler code
21922
Product ID
21922-045_6ffc01fa-3cf5-4e6c-9760-7ff9873c82df
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Mesalamine
Dosage form
SUSPENSION
Route
RECTAL
Labeler
Encube Ethicals, Inc.
Application
ANDA216941
Marketing category
ANDA
Marketing start
2023-06-01
Substance
MESALAMINE
Active strength
4 g/60mL
Pharmacologic classes
Aminosalicylate [EPC], Aminosalicylic Acids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216941-001MESALAMINEMESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A216941-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-308072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-303f0d92c62455…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216941-001MESALAMINE4GM/60MLENEMA / RECTALAB2023-05-30a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A216941-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216941-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216941-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216941-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216941-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216941-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216941-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216941-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216941-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216941-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216941-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216941-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216941-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216941-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216941-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216941-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216941-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216941-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216941-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216941-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216941-001AB13f0d92c62455…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216941-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Mesalamine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MESALAMINE4 g/60mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4Q81I59GXCInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
238151Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d6b68275-b2a4-4965-9862-cf14acf8c599Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c403bb07-2e2f-647c-b633-3f06ae7ddbe3Product name320260128
37997c2c-8686-b078-51f1-fb15da0c0a1cProduct name620260127
d9771140-739b-484b-ae64-b79528ff1211Product name320250801
97851e97-0a12-4d74-aaa4-9583fe070304Product name220250318
194d5e54-52c4-1a5e-51c5-1224f8e44e49Product name520250317
4b8d62b1-86bf-0c4e-9f22-ebffb45e4564Product name520240514
f6c01aa7-7e2c-4709-91b6-fc6ece37a7b3Product name120230124
a4dbd90c-f616-c999-40d7-60da88952163Product name220190802
77831c26-5062-ed63-fc15-a07600377b5bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
21922-045-01Mesalamine60 mL in 1 BOTTLE, DISPENSINGSUSPENSION606
21922-045-47Mesalamine7 in 1 CARTONSUSPENSION76
21922-045-49Mesalamine28 in 1 CARTONSUSPENSION286

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
21922-045-47ML - Milliliter21922-045a3151a33-d466-4e36-a281-5635e7be51f612023-08-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
21922-045MESALAMINE SUSPENSION [ENCUBE ETHICALS PRIVATE LIMITED]4Current NDC, 3 package rows20240808_d6b68275-b2a4-4965-9862-cf14acf8c599.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MesalamineMESALAMINEEncube Ethicals, Inc.d6b68275-b2a4-4965-9862-cf14acf8c5992025-10-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216941
application number: ANDA216941
ndc (product): 21922-045
MesalamineMESALAMINEBryant Ranch Prepackc9b1ef9d-1d06-48e7-87d2-7985b99124a62024-05-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216941
application number: ANDA216941

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
238151mesalamine 4 GM in 60 mL EnemaPSNc9b1ef9d-1d06-48e7-87d2-7985b99124a6101
238151mesalamine 66.7 MG/ML EnemaSCDc9b1ef9d-1d06-48e7-87d2-7985b99124a6101
238151mesalamine 4 GM per 60 ML EnemaSYc9b1ef9d-1d06-48e7-87d2-7985b99124a6101
238151mesalazine 66.7 MG/ML EnemaSYc9b1ef9d-1d06-48e7-87d2-7985b99124a6101
238151mesalamine 4 GM in 60 mL EnemaPSNd6b68275-b2a4-4965-9862-cf14acf8c5996
238151mesalamine 66.7 MG/ML EnemaSCDd6b68275-b2a4-4965-9862-cf14acf8c5996
238151mesalamine 4 GM per 60 ML EnemaSYd6b68275-b2a4-4965-9862-cf14acf8c5996
238151mesalazine 66.7 MG/ML EnemaSYd6b68275-b2a4-4965-9862-cf14acf8c5996

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
21922-045-012192200450160 mL in 1 BOTTLE, DISPENSING60 mlHistorical
21922-045-47219220045477 BOTTLE, DISPENSING in 1 CARTON (21922-045-47) / 60 mL in 1 BOTTLE, DISPENSING (21922-045-01) 2023-06-01NoNoCurrent
21922-045-492192200454928 BOTTLE, DISPENSING in 1 CARTON (21922-045-49) / 60 mL in 1 BOTTLE, DISPENSING (21922-045-01) 2023-06-01NoNoCurrent