Home NDC 23155-517 Neostigmine Methylsulfate
Product NDC 23155-517
11-digit product format 231550517
Labeler code 23155
Product ID 23155-517_fe40568f-ed8b-43fe-987f-839427a5924f
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name Neostigmine Methylsulfate
Dosage form INJECTION
Route INTRAVENOUS
Labeler Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Application ANDA208230
Marketing category ANDA
Marketing start 2022-11-25
Substance NEOSTIGMINE METHYLSULFATE
Active strength .5 mg/mL
Pharmacologic classes Cholinesterase Inhibitor [EPC], Cholinesterase Inhibitors [MoA]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 2 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date A208230-001 NEOSTIGMINE METHYLSULFATE NEOSTIGMINE METHYLSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 A208230-002 NEOSTIGMINE METHYLSULFATE NEOSTIGMINE METHYLSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25
Therapeutic equivalence codes# Current TE-code rows page 1 of 1 · 2 matching rows.
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 48 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-02-19 14:30 UTC 2026-02 A208230-001 NEOSTIGMINE METHYLSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 A208230-002 NEOSTIGMINE METHYLSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 A208230-001 NEOSTIGMINE METHYLSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 A208230-002 NEOSTIGMINE METHYLSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 A208230-001 NEOSTIGMINE METHYLSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 A208230-002 NEOSTIGMINE METHYLSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 d06236e962d9…2024-10-29 15:01 UTC 2024-10 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 79d66fd596c7…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 301d65b070ca…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 1e350fbaab3a…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 8072bd15b7f6…2024-05-31 18:47 UTC 2024-05 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 8072bd15b7f6…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 6a51e52b5d6a…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 1c564ffb4f44…2024-02-18 07:12 UTC 2024-02 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 ea1830bbd6c7…2023-12-20 04:57 UTC 2023-12 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 a72a2bbeb626…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 9b2671bbb829…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 A208230-001 NEOSTIGMINE METHYSULFATE 5MG/10ML (0.5MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 a67488948f0b…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 A208230-002 NEOSTIGMINE METHYSULFATE 10MG/10ML (1MG/ML) SOLUTION / INTRAVENOUS AP 2022-11-25 a67488948f0b…
Observed Orange Book normalized TE history# Normalized TE history page 1 of 2 · 48 observed states.
openFDA label cross-check# Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
Additional Listing Data#
Finished product Yes
Brand name base Neostigmine Methylsulfate
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength NEOSTIGMINE METHYLSULFATE .5 mg/mL
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 98IMH7M386 Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 311935 Internal RxNorm lookup 311936 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 23155-517-31 Neostigmine Methylsulfate 10 mL in 1 VIAL INJECTION 10 8 23155-517-41 Neostigmine Methylsulfate 10 in 1 CARTON INJECTION 10 8
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 23155-517 NEOSTIGMINE METHYLSULFATE INJECTION [HERITAGE PHARMACEUTICALS INC. D/B/A AVET PHARMACEUTICALS INC.] 7 Current NDC, Legacy NDC, 2 package rows 20240620_9cc2bfa1-c968-4d01-8162-2ef188974164.zip
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 23155-517-31 23155051731 10 mL in 1 VIAL 10 ml Historical 23155-517-41 23155051741 10 VIAL in 1 CARTON (23155-517-41) / 10 mL in 1 VIAL (23155-517-31) 10 vial 2022-11-25 0000-00-00 No No Current