Dihydroergotamine Mesylate

Product NDC
24201-463
11-digit product format
242010463
Labeler code
24201
Product ID
24201-463_d9b07b6a-d574-4490-8294-8727e7a004af
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Dihydroergotamine Mesylate
Dosage form
SPRAY
Route
NASAL
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA211393
Marketing category
ANDA
Marketing start
2020-04-14
Substance
DIHYDROERGOTAMINE MESYLATE
Active strength
4 mg/mL
Pharmacologic classes
Ergotamine Derivative [EPC], Ergotamines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211393-001DIHYDROERGOTAMINE MESYLATEDIHYDROERGOTAMINE MESYLATE0.5MG/SPRAYSPRAY, METERED / NASALAB2020-02-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211393-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06A211393-001DIHYDROERGOTAMINE MESYLATE0.5MG/SPRAYSPRAY, METERED / NASALAB2020-02-28a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-01 22:54:322026-06A211393-001AB1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Dihydroergotamine MesylateDIHYDROERGOTAMINE MESYLATEHikma Pharmaceuticals USA Inc.9ffe6d5a-7348-0498-e053-2a95a90a97a82025-12-12Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211393
application number: ANDA211393
ndc (product): 24201-463

Additional Listing Data#

Finished product
Yes
Brand name base
Dihydroergotamine Mesylate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIHYDROERGOTAMINE MESYLATE4 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
81AXN7R2QTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
861668Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9ffe6d5a-7348-0498-e053-2a95a90a97a8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
45c9a995-456f-4920-9be6-19f388510405Product name120260303
0dc20644-8d0b-4adf-9269-872bb65fd7fbProduct name320251205
803e1b3a-35b6-0bc8-229b-d2f7e8a7ffd4Product name520250516
7dea7767-9f52-b60a-5435-33cb9cc28baeProduct name420250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4Product name720250116
0ca83774-3f79-b837-5d6f-c210102f3bc8Product name620250114
cb89b86a-369e-4204-8910-ae797c503af3Product name120230706
41b814f3-0166-1c53-c9ef-a0794c7daf9dProduct name320221110
a590be26-846c-8659-a5a1-fb25907965dcProduct name220221110
2053edd2-6ad3-4897-ba63-817235bdab3cProduct name220220309
2dc76302-91c0-4c35-ad78-99adfb049c4bProduct name120200603
d4880ace-a516-8c47-8dfd-73a4ba5887d7Product name220180830
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
e6065d4b-5ae1-476f-a40e-f2851cbb5d2bProduct name220180221
f212291f-05fe-9603-fc7e-bd73e38ce1e6Product name220161129
182f9ab4-4ab5-c449-200f-87ce2ce8e550Product name220151105
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
332e86c3-7875-ca6e-f934-2206d2b31996Product name120140508
56625fcc-aa34-9d30-d0e9-1c1beb37ea21Product name120140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092Product name120140508
96c2be53-8e44-452d-56a2-d255b2f1af2dProduct name120140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44Product name120140508
d223c173-c39b-d764-47d4-d671d3088815Product name120140508
e01133ad-4dcd-c7f3-454b-2ff569ee160aProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
24201-463-08Dihydroergotamine Mesylate1 mL in 1 VIALSPRAY18
24201-463-08Dihydroergotamine Mesylate8 in 1 CARTONSPRAY88

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
24201-463-01ML - Milliliter24201-463929044a1-5aa8-41a9-80a9-584eb7aaf41812020-05-08
24201-463-08ML - Milliliter24201-463687b1e12-032c-46ad-a0d7-9ddf5004b4ad12020-05-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
24201-463DIHYDROERGOTAMINE MESYLATE SPRAY [HIKMA PHARMACEUTICALS USA INC.]7Current NDC, Legacy NDC, 2 package rows20241228_9ffe6d5a-7348-0498-e053-2a95a90a97a8.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861668dihydroergotamine mesylate 4 MG/mL Metered Dose Nasal SprayPSN9ffe6d5a-7348-0498-e053-2a95a90a97a88
861668dihydroergotamine mesylate 0.5 MG/ACTUAT Metered Dose Nasal SpraySCD9ffe6d5a-7348-0498-e053-2a95a90a97a88
861668DHE Mesylate 0.5 MG/ACTUAT Metered Dose Nasal SpraySY9ffe6d5a-7348-0498-e053-2a95a90a97a88
861668dihydroergotamine mesylate 0.5 MG/ACTUAT (4 MG/ML) Metered Dose Nasal SpraySY9ffe6d5a-7348-0498-e053-2a95a90a97a88

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
24201-463-01242010463011 VIAL in 1 KIT (24201-463-01) > 1 mL in 1 VIAL1 vial2020-04-140000-00-00NoNoCurrent
24201-463-08242010463088 VIAL in 1 CARTON (24201-463-08) / 1 mL in 1 VIAL8 vial2020-04-140000-00-00NoNoCurrent