Zestril

Product NDC: 24979-241
11-digit product format: 249790241
Labeler code: 24979
Product ID: 24979-241_7875efff-59e3-4f68-84c5-e3c9c16d6a3c
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Lisinopril
Dosage form: TABLET
Route: ORAL
Labeler: Upsher-Smith Laboratories, LLC
Application: NDA019777
Marketing category: NDA
Marketing start: 2024-04-25
Substance: LISINOPRIL
Active strength: 20 mg/1
Pharmacologic classes: Angiotensin Converting Enzyme Inhibitor [EPC], Angiotensin-converting Enzyme Inhibitors [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N019777-001	ZESTRIL	LISINOPRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19
N019777-002	ZESTRIL	LISINOPRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19
N019777-003	ZESTRIL	LISINOPRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19
N019777-004	ZESTRIL	LISINOPRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19
N019777-005	ZESTRIL	LISINOPRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29
N019777-006	ZESTRIL	LISINOPRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 6 matching rows.

Application-product, TE code table
Application-product	TE code
N019777-001	AB
N019777-002	AB
N019777-003	AB
N019777-004	AB
N019777-005	AB
N019777-006	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-005	ZESTRIL	2.5MG	TABLET / ORAL	AB	RLD	1993-04-29	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-006	ZESTRIL	30MG	TABLET / ORAL	AB	RLD	1999-01-20	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-001	ZESTRIL	5MG	TABLET / ORAL	AB	RLD	1988-05-19	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-002	ZESTRIL	10MG	TABLET / ORAL	AB	RLD	1988-05-19	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-003	ZESTRIL	20MG	TABLET / ORAL	AB	RLD	1988-05-19	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-004	ZESTRIL	40MG	TABLET / ORAL	AB	RLD, RS	1988-05-19	`03ed91905a0d…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-08-18 06:07:40	2026-07	N019777-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-002	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-003	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-004	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-005	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019777-006	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N019777-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-002	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-003	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-004	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-005	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019777-006	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-002	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-003	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-004	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-005	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019777-006	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N019777-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-002	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-003	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-004	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-005	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019777-006	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-002	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-003	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-004	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-005	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019777-006	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-002	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-003	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-004	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-005	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019777-006	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-002	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-003	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019777-004	AB	1	`03ed91905a0d…`

Additional Listing Data#

Finished product: Yes
Brand name base: Zestril
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
LISINOPRIL	20 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
E7199S1YWR	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 12 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
104375	Internal RxNorm lookup
104376	Internal RxNorm lookup
104377	Internal RxNorm lookup
104378	Internal RxNorm lookup
197884	Internal RxNorm lookup
205326	Internal RxNorm lookup
206771	Internal RxNorm lookup
213482	Internal RxNorm lookup
311353	Internal RxNorm lookup
311354	Internal RxNorm lookup
314076	Internal RxNorm lookup
314077	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f8f05a6d-f74b-4e9e-ab1c-374d3b4fb820	Product name	1	20230703
f65307a7-3644-0a09-cdfd-94aae8d3b53e	Product name	3	20210902
1bdb87cf-9b1f-6a51-5eb7-d182aaffaa3d	Product name	2	20170719

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
24979-241-07	Zestril	90 in 1 BOTTLE	TABLET	90		2

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
24979-241-07	EA - Each	24979-241	dec83518-c99b-4bdf-b004-065cb9c38104	1	2025-01-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
24979-241	ZESTRIL (LISINOPRIL) TABLET [UPSHER-SMITH LABORATORIES, LLC]	2	Current NDC, 1 package rows	20250503_838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Zestril	LISINOPRIL	Upsher-Smith Laboratories, LLC	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2025-01-02	Boxed warning, Warnings, Adverse reactions	Exact identifier application applno (NDA): 019777 application number: NDA019777 ndc (product): 24979-241

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
E7199S1YWR	LISINOPRIL	83915-83-7	LISINOPRIL

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
314076	lisinopril 10 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
311353	lisinopril 2.5 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
314077	lisinopril 20 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
205326	lisinopril 30 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
197884	lisinopril 40 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
311354	lisinopril 5 MG Oral Tablet	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104377	Zestril 10 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104375	Zestril 2.5 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104378	Zestril 20 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
213482	Zestril 30 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
206771	Zestril 40 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104376	Zestril 5 MG Oral Tablet, Once-Daily	PSN	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104377	lisinopril 10 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104375	lisinopril 2.5 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104378	lisinopril 20 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
213482	lisinopril 30 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
206771	lisinopril 40 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104376	lisinopril 5 MG Oral Tablet [Zestril]	SBD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
314076	lisinopril 10 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
311353	lisinopril 2.5 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
314077	lisinopril 20 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
205326	lisinopril 30 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
197884	lisinopril 40 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
311354	lisinopril 5 MG Oral Tablet	SCD	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104377	Zestril 10 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104375	Zestril 2.5 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104378	Zestril 20 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
213482	Zestril 30 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
206771	Zestril 40 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2
104376	Zestril 5 MG Oral Tablet	SY	838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
24979-241-07	24979024107	90 TABLET in 1 BOTTLE (24979-241-07)	90 tablet	2024-04-25	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Zestril	Upsher-Smith Laboratories, LLC \| TWi Pharmaceuticals, Inc. \| Norwich Pharmaceuticals, Inc.	2025-01-02	HUMAN PRESCRIPTION DRUG LABEL	2