Timoptic

Product NDC
25010-815
11-digit product format
250100815
Labeler code
25010
Product ID
25010-815_0f32f82b-4e6e-4958-9124-f97451ae3e20
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Timolol Maleate
Dosage form
SOLUTION
Route
OPHTHALMIC
Labeler
Aton Pharma, Inc.
Application
NDA019463
Marketing category
NDA
Marketing start
1986-11-05
Marketing end
0000-00-00
Substance
TIMOLOL MALEATE
Active strength
5 mg/mL
NDC exclude flag
E
Listing certified through
2017-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct25010-815DDiscontinued by firm2026-08-17
excluded packagepackage25010-81525010-815-66DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 30 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCCodeStatusSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductDDiscontinued by firmd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage25010-815-66DDiscontinued by firmd630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductDDiscontinued by firmf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage25010-815-66DDiscontinued by firmf5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproductDDiscontinued by firm2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage25010-815-66DDiscontinued by firm2ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproductDDiscontinued by firma1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage25010-815-66DDiscontinued by firma1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductDDiscontinued by firmcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage25010-815-66DDiscontinued by firmcfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductDDiscontinued by firmcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage25010-815-66DDiscontinued by firmcdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproductDDiscontinued by firm302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage25010-815-66DDiscontinued by firm302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproductDDiscontinued by firmed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage25010-815-66DDiscontinued by firmed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproductDDiscontinued by firm0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage25010-815-66DDiscontinued by firm0efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductDDiscontinued by firmad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage25010-815-66DDiscontinued by firmad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproductDDiscontinued by firm367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage25010-815-66DDiscontinued by firm367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproductDDiscontinued by firm557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage25010-815-66DDiscontinued by firm557ba5c1ecfa…9c80585c8c6e…
2020-12-18 03:04 UTC · source 2020-12-17excluded productproductIInactivated by FDAe2bbac7714bc…27bdfed8d636…
2020-12-18 03:04 UTC · source 2020-12-17excluded packagepackage25010-815-66IInactivated by FDAe2bbac7714bc…27bdfed8d636…
2020-06-10 20:45 UTC · source 2020-06-10excluded productproductIInactivated by FDA9bebd1f3094a…5416666fcb17…
2020-06-10 20:45 UTC · source 2020-06-10excluded packagepackage25010-815-66IInactivated by FDA9bebd1f3094a…5416666fcb17…
2019-12-08 06:16 UTC · source 2019-12-05excluded productproductIInactivated by FDA110d247fa046…a55b01930146…
2019-12-08 06:16 UTC · source 2019-12-05excluded packagepackage25010-815-66IInactivated by FDA110d247fa046…a55b01930146…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019463-001TIMOPTIC IN OCUDOSETIMOLOL MALEATEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05
N019463-002TIMOPTIC IN OCUDOSETIMOLOL MALEATEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N019463-001AT3
N019463-002AT3

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05caaa826d4ba7…
2026-08-18 06:07:402026-07N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-052680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05d06236e962d9…
2024-10-29 15:01 UTC2024-10N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-051e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-058072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-054b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICRLD, RS1986-11-0574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICRLD, RS1986-11-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N019463-001TIMOPTIC IN OCUDOSEEQ 0.25% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N019463-002TIMOPTIC IN OCUDOSEEQ 0.5% BASESOLUTION/DROPS / OPHTHALMICAT3RLD, RS1986-11-05bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 71 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N019463-001AT31caaa826d4ba7…
2026-08-18 06:07:402026-07N019463-002AT31caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019463-001AT31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019463-002AT31011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019463-001AT3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019463-002AT3131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019463-001AT316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019463-002AT316a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019463-001AT31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019463-002AT31fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019463-001AT31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019463-002AT31b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019463-001AT3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019463-002AT3103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019463-001AT312680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019463-002AT312680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019463-001AT315bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019463-002AT315bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019463-001AT31d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019463-002AT31d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019463-001AT31d06236e962d9…
2024-10-29 15:01 UTC2024-10N019463-002AT31d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019463-001AT3179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019463-002AT3179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019463-001AT31301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019463-002AT31301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019463-001AT311e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019463-002AT311e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019463-001AT318072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019463-002AT318072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019463-001AT315c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019463-002AT315c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N019463-001AT315d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N019463-002AT315d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N019463-001AT314b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N019463-002AT314b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N019463-001AT31bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N019463-002AT31bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N019463-002AT31782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N019463-002AT3187673890dc5c…

FDA-Initiated Inactive NDC Indexing#

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25010-815-66EA - Each25010-815fd67e1c8-648c-40b6-a113-baced802f5c812012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
Timolol MaleateACTIVE INGREDIENTP8Y54F701RTIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2
TimololACTIVE MOIETY817W3C6175TIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2
Sodium HydroxideINACTIVE INGREDIENT55X04QC32ITIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2
Sodium Phosphate, DibasicINACTIVE INGREDIENTGR686LBA74TIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2
Sodium Phosphate, MonobasicINACTIVE INGREDIENT3980JIH2SWTIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2
WaterINACTIVE INGREDIENT059QF0KO0RTIMOPTIC (TIMOLOL MALEATE) SOLUTION [ATON PHARMA, INC.]2

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Timolol MaleateTIMOLOL MALEATEBausch & Lomb Americas Inc.036dc753-1698-4c69-9bcf-752c7061203c2025-03-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 019463
application number: NDA019463
Timoptic in OcudoseTIMOLOL MALEATEBausch & Lomb Incorporatedd130f0ec-c3b5-4bc3-8f4a-68fd6c3ec0cf2022-01-31Warnings, Adverse reactionsExact identifier
application applno (NDA): 019463
application number: NDA019463