fluorouracil

Product NDC
25021-215
11-digit product format
250210215
Labeler code
25021
Product ID
25021-215_223c5d8d-c064-4a0a-8490-b1c4aa0e706d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
fluorouracil
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA203609
Marketing category
ANDA
Marketing start
2016-09-15
Substance
FLUOROURACIL
Active strength
50 mg/mL
Pharmacologic classes
Nucleic Acid Synthesis Inhibitors [MoA], Nucleoside Metabolic Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203609-001FLUOROURACILFLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17
A203609-002FLUOROURACILFLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A203609-001AP
A203609-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17caaa826d4ba7…
2026-08-18 06:07:402026-07A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-172680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17d06236e962d9…
2024-10-29 15:01 UTC2024-10A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-171e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-178072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-174b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-174b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1774a2ff9319b5…
2019-12-13 00:20 UTC2019-12A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-1774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203609-001FLUOROURACIL2.5GM/50ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A203609-002FLUOROURACIL5GM/100ML (50MG/ML)INJECTABLE / INJECTIONAP2016-02-17bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A203609-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A203609-002AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A203609-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203609-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203609-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203609-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203609-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203609-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203609-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203609-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203609-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203609-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203609-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203609-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203609-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203609-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203609-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203609-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203609-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203609-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203609-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203609-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203609-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203609-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203609-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203609-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203609-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203609-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203609-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203609-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203609-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203609-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203609-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A203609-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203609-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A203609-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203609-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A203609-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203609-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A203609-002AP1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
fluorouracil
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
FLUOROURACIL50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
U3P01618RTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
239177Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
37e35e8c-5d51-413b-a3a0-b72a18caaf65Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7dc9482d-9b87-4471-9708-4f1b4585846bProduct name220250723
a2ca0bf8-8306-49cc-93a3-3e6e4137c7cbProduct name520250630
dc0d2364-4811-4665-a3ee-7ed8c7301465Product name220171219
62fb8671-1693-49d8-8aab-0c1bfdd6794eProduct name120151005
878ca466-81fd-9d24-1349-31baf36065c6Product name220150506
630d1bc2-ae6b-fd31-1264-c4733e788193Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-215-98fluorouracil1 in 1 CARTONINJECTION, SOLUTION19
25021-215-98fluorouracil50 mL in 1 BOTTLEINJECTION, SOLUTION509
25021-215-99fluorouracil100 mL in 1 BOTTLEINJECTION, SOLUTION1009
25021-215-99fluorouracil1 in 1 CARTONINJECTION, SOLUTION19

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-215-98ML - Milliliter25021-215d6310bdd-544e-40c7-945c-00d04d04937812016-10-06
25021-215-99ML - Milliliter25021-21585936e14-3fd5-46b3-ab1f-36b4f8bd7c4712016-10-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-215FLUOROURACIL INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]8Current NDC, Legacy NDC, 4 package rows20240507_37e35e8c-5d51-413b-a3a0-b72a18caaf65.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
fluorouracilFLUOROURACILSagent Pharmaceuticals37e35e8c-5d51-413b-a3a0-b72a18caaf652026-02-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203609
application number: ANDA203609
ndc (product): 25021-215

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
239177fluorouracil 50 MG/ML Injectable SolutionPSN37e35e8c-5d51-413b-a3a0-b72a18caaf659
239177fluorouracil 50 MG/ML Injectable SolutionSCD37e35e8c-5d51-413b-a3a0-b72a18caaf659
2391775-5-fluorouracil 50 MG/ML Injectable SolutionSY37e35e8c-5d51-413b-a3a0-b72a18caaf659
2391775-FU 50 MG/ML Injectable SolutionSY37e35e8c-5d51-413b-a3a0-b72a18caaf659
239177fluorouracil (as fluorouracil sodium) 50 MG/ML Injectable SolutionSY37e35e8c-5d51-413b-a3a0-b72a18caaf659
239177fluorouracil 2.5 GM per 50 ML Injectable SolutionSY37e35e8c-5d51-413b-a3a0-b72a18caaf659

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
25021-215-98250210215981 BOTTLE in 1 CARTON (25021-215-98) / 50 mL in 1 BOTTLE1 bottle2016-09-150000-00-00NoNoCurrent
25021-215-99250210215991 BOTTLE in 1 CARTON (25021-215-99) / 100 mL in 1 BOTTLE1 bottle2016-09-150000-00-00NoNoCurrent