Procainamide Hydrochloride

Product NDC
25021-322
11-digit product format
250210322
Labeler code
25021
Product ID
25021-322_65bd5a24-3fbb-4264-b26f-5839143936db
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Procainamide Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA218135
Marketing category
ANDA
Marketing start
2025-01-15
Substance
PROCAINAMIDE HYDROCHLORIDE
Active strength
100 mg/mL
Pharmacologic classes
Antiarrhythmic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218135-001PROCAINAMIDE HYDROCHLORIDEPROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAPRS2024-07-22
A218135-002PROCAINAMIDE HYDROCHLORIDEPROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAPRS2024-07-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A218135-001AP
A218135-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAPRS2024-07-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAPRS2024-07-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-225bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-22d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-22d06236e962d9…
2024-10-29 15:01 UTC2024-10A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAP2024-07-2279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAP2024-07-2279d66fd596c7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218135-001PROCAINAMIDE HYDROCHLORIDE100MG/MLINJECTABLE / INJECTIONAPRS2024-07-22a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218135-002PROCAINAMIDE HYDROCHLORIDE500MG/MLINJECTABLE / INJECTIONAPRS2024-07-22a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A218135-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A218135-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218135-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218135-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A218135-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A218135-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218135-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218135-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218135-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A218135-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218135-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A218135-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218135-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A218135-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218135-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A218135-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218135-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A218135-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A218135-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A218135-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A218135-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A218135-002AP179d66fd596c7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218135-001AP1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218135-002AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Procainamide Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROCAINAMIDE HYDROCHLORIDE100 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
SI4064O0LXInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
857886Internal RxNorm lookup
857962Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
358c956e-8c6c-4bd6-a6bc-194d5b3d6d9aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
67853295-be49-b731-d597-94f59291a90cProduct name320250311

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-322-10Procainamide Hydrochloride10 mL in 1 VIALINJECTION, SOLUTION101
25021-322-10Procainamide Hydrochloride10 in 1 CARTONINJECTION, SOLUTION101

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-322-10ML - Milliliter25021-322fba6209d-e1f8-4f4c-a14b-fc9fa3a67b1812025-03-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-322PROCAINAMIDE HYDROCHLORIDE INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]1Current NDC, 2 package rows20250115_358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Procainamide HydrochloridePROCAINAMIDE HYDROCHLORIDEMedical Purchasing Solutions, LLC.42405567-3d04-7aec-e063-6294a90aba0a2025-10-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218135
application number: ANDA218135
Procainamide HydrochloridePROCAINAMIDE HYDROCHLORIDESagent Pharmaceuticals358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a2024-12-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218135
application number: ANDA218135
ndc (product): 25021-322
Procainamide HydrochloridePROCAINAMIDE HYDROCHLORIDEGland Pharma Limitedffde440f-7ad7-434c-bcd2-9bd8ff16d2042024-07-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218135
application number: ANDA218135

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
857886procainamide HCl 100 MG/ML Injectable SolutionPSN358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a1
857886procainamide HCl 100 MG/ML Injectable SolutionPSN42405567-3d04-7aec-e063-6294a90aba0a1
857962procainamide HCl 500 MG/ML Injectable SolutionPSN358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a1
857886procainamide hydrochloride 100 MG/ML Injectable SolutionSCD358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a1
857886procainamide hydrochloride 100 MG/ML Injectable SolutionSCD42405567-3d04-7aec-e063-6294a90aba0a1
857962procainamide hydrochloride 500 MG/ML Injectable SolutionSCD358c956e-8c6c-4bd6-a6bc-194d5b3d6d9a1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
25021-322-102502103221010 VIAL in 1 CARTON (25021-322-10) / 10 mL in 1 VIAL10 vial2025-01-15NoNoCurrent