propofol

Product NDC
25021-608
11-digit product format
250210608
Labeler code
25021
Product ID
25021-608_24f96546-ad32-43ca-be91-5536e26d4137
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
propofol
Dosage form
INJECTION, EMULSION
Route
INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA075102
Marketing category
ANDA
Marketing start
2014-07-01
Substance
PROPOFOL
Active strength
10 mg/mL
Pharmacologic classes
General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A075102-001PROPOFOLPROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A075102-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-0487673890dc5c…
2021-03-12 10:30 UTC2021-03A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-045aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-048869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-043f01610625f2…
2019-09-15 20:21 UTC2019-09A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04b00525d2431f…
2019-07-19 19:46 UTC2019-07A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075102-001PROPOFOL10MG/MLINJECTABLE / INJECTIONAB1999-01-04e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A075102-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A075102-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075102-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A075102-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075102-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075102-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075102-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075102-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075102-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075102-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075102-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075102-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075102-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075102-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075102-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075102-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075102-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075102-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075102-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075102-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075102-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075102-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A075102-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075102-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075102-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075102-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A075102-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A075102-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075102-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075102-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075102-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075102-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075102-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075102-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075102-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A075102-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A075102-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075102-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075102-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075102-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
propofol
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROPOFOL10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
YI7VU623SFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1808217Internal RxNorm lookup
1808222Internal RxNorm lookup
1808224Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fa93f173-7858-4d88-860e-76ab97e65c2fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b5dd1a36-1efc-430d-94c2-9f49a850da5fProduct name620250317
baf7f49c-75b6-496b-a00e-8e766a8e4f03Product name120210127
ebc62596-fc97-4d03-9483-7ba095d25db7Product name120151210
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-608-20propofol20 mL in 1 VIALINJECTION, EMULSION2010
25021-608-20propofol25 in 1 CARTONINJECTION, EMULSION2510
25021-608-50propofol20 in 1 CARTONINJECTION, EMULSION2010
25021-608-50propofol50 mL in 1 VIALINJECTION, EMULSION5010
25021-608-51propofol100 mL in 1 VIALINJECTION, EMULSION10010
25021-608-51propofol10 in 1 CARTONINJECTION, EMULSION1010

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-608-20ML - Milliliter25021-6084e2e8ce2-ea05-458a-8695-4d82162ef1b312014-12-01
25021-608-50ML - Milliliter25021-6082c251ea1-2608-44c4-89e3-125a478aa6ce12015-04-03
25021-608-51ML - Milliliter25021-6085a9f2202-bed2-4aff-b2f7-38306a07141f12014-11-05

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
propofolACTIVE INGREDIENTYI7VU623SFPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
propofolACTIVE MOIETYYI7VU623SFPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
egg phospholipidsINACTIVE INGREDIENT1Z74184RGVPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
glycerinINACTIVE INGREDIENTPDC6A3C0OXPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
sodium hydroxideINACTIVE INGREDIENT55X04QC32IPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
sodium metabisulfiteINACTIVE INGREDIENT4VON5FNS3CPROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3
soybean oilINACTIVE INGREDIENT241ATL177APROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-608PROPOFOL INJECTION, EMULSION [SAGENT PHARMACEUTICALS]9Current NDC, Legacy NDC, 6 package rows20230629_fa93f173-7858-4d88-860e-76ab97e65c2f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
propofolPROPOFOLSagent Pharmaceuticalsfa93f173-7858-4d88-860e-76ab97e65c2f2025-06-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075102
application number: ANDA075102
ndc (product): 25021-608

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1808217propofol 1000 MG in 100 ML InjectionPSNfa93f173-7858-4d88-860e-76ab97e65c2f10
1808224propofol 200 MG in 20 ML InjectionPSNfa93f173-7858-4d88-860e-76ab97e65c2f10
1808222propofol 500 MG in 50 ML InjectionPSNfa93f173-7858-4d88-860e-76ab97e65c2f10
1808217100 ML propofol 10 MG/ML InjectionSCDfa93f173-7858-4d88-860e-76ab97e65c2f10
180822420 ML propofol 10 MG/ML InjectionSCDfa93f173-7858-4d88-860e-76ab97e65c2f10
180822250 ML propofol 10 MG/ML InjectionSCDfa93f173-7858-4d88-860e-76ab97e65c2f10
1808217propofol 1000 MG per 100 ML InjectionSYfa93f173-7858-4d88-860e-76ab97e65c2f10
1808224propofol 200 MG per 20 ML InjectionSYfa93f173-7858-4d88-860e-76ab97e65c2f10
1808222propofol 500 MG per 50 ML InjectionSYfa93f173-7858-4d88-860e-76ab97e65c2f10

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
25021-608-202502106082025 VIAL in 1 CARTON (25021-608-20) / 20 mL in 1 VIAL25 vial2014-07-010000-00-00NoNoCurrent
25021-608-502502106085020 VIAL in 1 CARTON (25021-608-50) / 50 mL in 1 VIAL20 vial2014-07-010000-00-00NoNoCurrent
25021-608-512502106085110 VIAL in 1 CARTON (25021-608-51) / 100 mL in 1 VIAL10 vial2014-07-010000-00-00NoNoCurrent