Magnesium Sulfate

Product NDC
25021-612
11-digit product format
250210612
Labeler code
25021
Product ID
25021-612_f91b940b-e459-46c8-886a-c1da0265da54
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Magnesium Sulfate Heptahydrate
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA213917
Marketing category
ANDA
Marketing start
2021-02-15
Substance
MAGNESIUM SULFATE HEPTAHYDRATE
Active strength
40 mg/mL
Pharmacologic classes
Calculi Dissolution Agent [EPC], Increased Large Intestinal Motility [PE], Inhibition Large Intestine Fluid/Electrolyte Absorption [PE], Inhibition Small Intestine Fluid/Electrolyte Absorption [PE], Magnesium Ion Exchange Activity [MoA], Osmotic Activity [MoA], Osmotic Laxative [EPC], Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINERMAGNESIUM SULFATE2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10
A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINERMAGNESIUM SULFATE4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A213917-001AP
A213917-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 76 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10caaa826d4ba7…
2026-08-18 06:07:402026-07A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10d06236e962d9…
2024-10-29 15:01 UTC2024-10A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-101e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-108072bd15b7f6…
2024-05-31 18:47 UTC2024-05A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-108072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-105d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-104b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-104b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213917-001MAGNESIUM SULFATE IN PLASTIC CONTAINER2GM/50ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10782e0a99824c…
2021-12-28 21:50 UTC2021-12A213917-002MAGNESIUM SULFATE IN PLASTIC CONTAINER4GM/100ML (40MG/ML)INJECTABLE / INJECTIONAP2020-07-10782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 76 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A213917-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A213917-002AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A213917-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A213917-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213917-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A213917-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A213917-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A213917-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213917-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A213917-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213917-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A213917-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213917-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A213917-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213917-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A213917-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213917-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A213917-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213917-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A213917-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A213917-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A213917-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213917-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A213917-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213917-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A213917-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213917-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A213917-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A213917-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A213917-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213917-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A213917-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A213917-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A213917-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A213917-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A213917-002AP14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A213917-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A213917-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A213917-001AP1782e0a99824c…
2021-12-28 21:50 UTC2021-12A213917-002AP1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Magnesium Sulfate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MAGNESIUM SULFATE HEPTAHYDRATE40 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
SK47B8698TInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1658259Internal RxNorm lookup
1658262Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a607796c-6676-4d0a-8108-8708fe6769edAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6e3c022f-0786-43f1-8857-edff89d5153fProduct name120260309
95250459-30e4-45c1-b08a-993044f49109Product name220250805
efd58652-cb8f-4018-91ca-4b0eb2ff729fProduct name720240226
362d7abb-94e6-4c60-9a58-266894157713Product name120231023
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
6bd95106-a412-1dad-b9cc-4cb74bfb27ceProduct name220230315
9badc7be-250a-44ab-aa36-926af3f02679Product name120210527
2641ccb3-721d-4fbf-9f2f-ca2f18157a62Product name320210309
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
26acd337-b838-40ac-bcbc-05c3b81c8712Product name120170323
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
290f523a-f9db-9774-b5a9-e1f908ac1782Product name120150828
e7e58cd3-cacb-49df-8d34-1ee335614abbProduct name120150609
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
c6b65c52-69c7-df49-550a-a50c137f6218Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-612-81Magnesium Sulfate50 mL in 1 BAGINJECTION, SOLUTION501
25021-612-81Magnesium Sulfate10 in 1 CARTONINJECTION, SOLUTION101
25021-612-82Magnesium Sulfate10 in 1 CARTONINJECTION, SOLUTION101
25021-612-82Magnesium Sulfate100 mL in 1 BAGINJECTION, SOLUTION1001

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-612-81ML - Milliliter25021-612d0b6eb28-d718-4f07-8788-1e3bd80128ef12021-05-05
25021-612-82ML - Milliliter25021-61281de6140-fa14-4125-babb-fd21bcbe16a412021-05-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-612MAGNESIUM SULFATE (MAGNESIUM SULFATE HEPTAHYDRATE) INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]1Current NDC, Legacy NDC, 4 package rows20210215_a607796c-6676-4d0a-8108-8708fe6769ed.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MAGNESIUM SULFATEMAGNESIUM SULFATE HEPTAHYDRATESun Pharmaceutical Industries, Inc.efadcb55-f935-4c60-b2e2-0a76b9194b502026-01-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213917
application number: ANDA213917
Magnesium SulfateMAGNESIUM SULFATE HEPTAHYDRATESagent Pharmaceuticalsa607796c-6676-4d0a-8108-8708fe6769ed2020-11-16Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213917
application number: ANDA213917
ndc (product): 25021-612
MAGNESIUM SULFATEMAGNESIUM SULFATE HEPTAHYDRATEGland Pharma Limiteda9e706ac-9c5f-4b14-b277-53dee195ffc62020-07-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 213917
application number: ANDA213917

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1658259magnesium sulfate 2 GM in 50 ML InjectionPSNa607796c-6676-4d0a-8108-8708fe6769ed1
1658262magnesium sulfate 4 GM in 100 ML InjectionPSNa607796c-6676-4d0a-8108-8708fe6769ed1
1658262100 ML magnesium sulfate 40 MG/ML InjectionSCDa607796c-6676-4d0a-8108-8708fe6769ed1
165825950 ML magnesium sulfate 40 MG/ML InjectionSCDa607796c-6676-4d0a-8108-8708fe6769ed1
1658259magnesium sulfate 2 GM per 50 ML InjectionSYa607796c-6676-4d0a-8108-8708fe6769ed1
1658262magnesium sulfate 4 GM per 100 ML InjectionSYa607796c-6676-4d0a-8108-8708fe6769ed1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
25021-612-812502106128110 BAG in 1 CARTON (25021-612-81) / 50 mL in 1 BAG10 bag2021-02-150000-00-00NoNoCurrent
25021-612-822502106128210 BAG in 1 CARTON (25021-612-82) / 100 mL in 1 BAG10 bag2021-02-150000-00-00NoNoCurrent