Ketamine Hydrochloride

Product NDC
25021-684
11-digit product format
250210684
Labeler code
25021
Product ID
25021-684_51a16c65-47e0-405c-8c84-82a6a28b3efd
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ketamine Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA216809
Marketing category
ANDA
Marketing start
2023-07-15
Substance
KETAMINE HYDROCHLORIDE
Active strength
100 mg/mL
Pharmacologic classes
General Anesthesia [PE], General Anesthetic [EPC]
DEA schedule
CIII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216809-001KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24
A216809-002KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24
A216809-003KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A216809-001AP
A216809-002AP
A216809-003AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 75 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2484e616aacf4f…
2026-09-14 22:38:342026-08A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2484e616aacf4f…
2026-09-14 22:38:342026-08A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2484e616aacf4f…
2026-08-18 06:07:402026-07A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24caaa826d4ba7…
2026-08-18 06:07:402026-07A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24caaa826d4ba7…
2026-08-18 06:07:402026-07A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d06236e962d9…
2024-10-29 15:01 UTC2024-10A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d06236e962d9…
2024-10-29 15:01 UTC2024-10A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-002KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-003KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP2023-01-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216809-001KETAMINE HYDROCHLORIDEEQ 10MG BASE/MLINJECTABLE / INJECTIONAP2023-01-24301d65b070ca…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 75 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-09-14 22:38:342026-08A216809-001AP184e616aacf4f…
2026-09-14 22:38:342026-08A216809-002AP184e616aacf4f…
2026-09-14 22:38:342026-08A216809-003AP184e616aacf4f…
2026-08-18 06:07:402026-07A216809-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A216809-002AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A216809-003AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A216809-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216809-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A216809-003AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216809-003AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216809-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216809-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A216809-003AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216809-003AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216809-003AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216809-003AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216809-003AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216809-003AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216809-003AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216809-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A216809-002AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A216809-003AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-002AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216809-003AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216809-001AP1301d65b070ca…

Additional Listing Data#

Finished product
Yes
Brand name base
Ketamine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
KETAMINE HYDROCHLORIDE100 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
O18YUO0I83Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
238082Internal RxNorm lookup
238083Internal RxNorm lookup
238084Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
902c3785-a3cb-472b-ac15-394ac646271dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bb4bf50b-0475-bcb2-86ff-7b0cc2cc55bcProduct name220240223

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-684-05Ketamine Hydrochloride10 in 1 CARTONINJECTION, SOLUTION101
25021-684-05Ketamine Hydrochloride5 mL in 1 VIALINJECTION, SOLUTION51

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-684-05ML - Milliliter25021-684249e8ab6-8410-45f2-8501-72fdd33b751f12023-12-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-684KETAMINE HYDROCHLORIDE INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]1Current NDC, 2 package rows20230715_902c3785-a3cb-472b-ac15-394ac646271d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Ketamine HydrochlorideKETAMINE HYDROCHLORIDEGland Pharma Limitedb96a0a23-3ca0-4a92-bd8b-1e99219317722026-04-16Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216809
application number: ANDA216809
Ketamine HydrochlorideKETAMINE HYDROCHLORIDESagent Pharmaceuticals902c3785-a3cb-472b-ac15-394ac646271d2023-05-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216809
application number: ANDA216809
ndc (product): 25021-684

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
238082ketamine 10 MG/ML Injectable SolutionPSN902c3785-a3cb-472b-ac15-394ac646271d1
238083ketamine 100 MG/ML Injectable SolutionPSN902c3785-a3cb-472b-ac15-394ac646271d1
238084ketamine 50 MG/ML Injectable SolutionPSN902c3785-a3cb-472b-ac15-394ac646271d1
238082ketamine 10 MG/ML Injectable SolutionSCD902c3785-a3cb-472b-ac15-394ac646271d1
238083ketamine 100 MG/ML Injectable SolutionSCD902c3785-a3cb-472b-ac15-394ac646271d1
238084ketamine 50 MG/ML Injectable SolutionSCD902c3785-a3cb-472b-ac15-394ac646271d1
238082ketamine (as ketamine hydrochloride) 10 MG/ML Injectable SolutionSY902c3785-a3cb-472b-ac15-394ac646271d1
238083ketamine (as ketamine hydrochloride) 100 MG/ML Injectable SolutionSY902c3785-a3cb-472b-ac15-394ac646271d1
238084ketamine (as ketamine hydrochloride) 50 MG/ML Injectable SolutionSY902c3785-a3cb-472b-ac15-394ac646271d1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
25021-684-052502106840510 VIAL in 1 CARTON (25021-684-05) / 5 mL in 1 VIAL10 vial2023-07-15NoNoCurrent