zoledronic acid

Product NDC
25021-826
Requested package NDC
25021-826-87
11-digit product format
250210826
Labeler code
25021
Product ID
25021-826_cd9bea2a-6045-452d-9ac5-e70d08e9e26f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
zoledronic acid
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
NDA203231
Marketing category
NDA
Marketing start
2013-03-02
Substance
ZOLEDRONIC ACID
Active strength
.04 mg/mL
Pharmacologic classes
Bisphosphonate [EPC], Diphosphonates [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N203231-001ZOLEDRONIC ACIDZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N203231-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-0231067a03dcf5…
2025-08-23 18:47 UTC2025-08N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-026a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-0203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-022680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-025bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-0279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-021e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-028072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-025c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-025d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-024b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-0274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-0287673890dc5c…
2021-03-12 10:30 UTC2021-03N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-025aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-028869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-023f01610625f2…
2019-09-15 20:21 UTC2019-09N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02b00525d2431f…
2019-07-19 19:46 UTC2019-07N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-026a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-021c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD, RS2013-08-02ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD2013-08-02a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAPRLD2013-08-029b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-023f0d92c62455…
2023-05-13 08:27 UTC2023-05N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02053a50430f4f…
2023-01-26 05:58 UTC2023-01N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-023bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-023a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N203231-001ZOLEDRONIC ACIDEQ 4MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-08-02cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N203231-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203231-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N203231-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203231-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203231-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203231-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203231-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203231-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203231-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203231-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203231-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203231-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203231-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203231-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203231-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203231-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203231-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203231-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203231-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203231-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203231-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03N203231-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203231-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203231-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203231-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09N203231-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07N203231-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203231-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203231-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203231-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203231-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203231-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N203231-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N203231-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05N203231-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01N203231-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N203231-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N203231-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N203231-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N203231-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
zoledronic acid
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ZOLEDRONIC ACID.04 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6XC1PAD3KFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1114085Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
567578e6-cd2d-4339-b0f6-7a15444c0639Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
963c7720-927d-e443-b968-0d27f7055a69Product name820240606
95fe9bf2-51a5-1324-90da-8451ccf59619Product name920190228
76bb2633-9686-4c41-9e21-c755e223f2e0Product name120160408
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
94acf8b5-886e-4cdd-b38e-791d5af82ba0Product name120150325

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-826-82zoledronic acid1 in 1 CARTONINJECTION, SOLUTION121
25021-826-82zoledronic acid100 mL in 1 BAGINJECTION, SOLUTION10021
25021-826-87zoledronic acid100 mL in 1 BAGINJECTION, SOLUTION10021
25021-826-87zoledronic acid5 in 1 CARTONINJECTION, SOLUTION521
25021-826-67zoledronic acid100 mL in 1 BAGINJECTION, SOLUTION10011
25021-826-67zoledronic acid1 in 1 CARTONINJECTION, SOLUTION111

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-826-66ML - Milliliter25021-826c3b61292-1a29-42b2-b9e8-51392e29cbec12015-12-02
25021-826-67ML - Milliliter25021-8266aed9593-17c3-4275-a905-06d2a806a0bb12015-12-02
25021-826-82ML - Milliliter25021-826c6494fa9-20fa-4709-8e4d-775aaaf7192f12013-09-04
25021-826-87ML - Milliliter25021-82699e78708-a56a-4f87-a754-086ba18e3aff12025-06-13

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-826ZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]21Current NDC, Legacy NDC, 4 package rows20250325_567578e6-cd2d-4339-b0f6-7a15444c0639.zip
25021-826ZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]11Current NDC, Legacy NDC, 2 package rows20220309_deb89be7-f40e-4fd4-a2cb-96634b45da84.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
zoledronic acidZOLEDRONIC ACIDSagent Pharmaceuticals567578e6-cd2d-4339-b0f6-7a15444c06392025-03-11Warnings, Adverse reactionsExact identifier
application applno (NDA): 203231
application number: NDA203231
ndc (package): 25021-826-87
ndc (product): 25021-826
ndc11 (package): 25021082687
zoledronic acidZOLEDRONIC ACIDSagent Pharmaceuticalsdeb89be7-f40e-4fd4-a2cb-96634b45da842021-09-20Warnings, Adverse reactionsExact identifier
application applno (NDA): 203231
application number: NDA203231
ndc (product): 25021-826

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1114085zoledronic acid 4 MG in 100 ML InjectionPSN567578e6-cd2d-4339-b0f6-7a15444c063921
1114085100 ML zoledronic acid 0.04 MG/ML InjectionSCD567578e6-cd2d-4339-b0f6-7a15444c063921
1114085zoledronic acid 4 MG per 100 ML InjectionSY567578e6-cd2d-4339-b0f6-7a15444c063921
1114085zoledronic acid 4 MG in 100 ML InjectionPSNdeb89be7-f40e-4fd4-a2cb-96634b45da8411
1114085100 ML zoledronic acid 0.04 MG/ML InjectionSCDdeb89be7-f40e-4fd4-a2cb-96634b45da8411
1114085zoledronic acid 4 MG per 100 ML InjectionSYdeb89be7-f40e-4fd4-a2cb-96634b45da8411

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
25021-826-87250210826875 BAG in 1 CARTON (25021-826-87) / 100 mL in 1 BAG5 bag2025-04-15NoNoCurrent