zoledronic acid

Product NDC
25021-830
11-digit product format
250210830
Labeler code
25021
Product ID
25021-830_dd7663fa-8a03-4717-a3fb-c4c03e6300e8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
zoledronic acid
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Sagent Pharmaceuticals
Application
ANDA202828
Marketing category
ANDA
Marketing start
2013-03-02
Substance
ZOLEDRONIC ACID
Active strength
.05 mg/mL
Pharmacologic classes
Bisphosphonate [EPC], Diphosphonates [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202828-001ZOLEDRONIC ACIDZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A202828-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-234b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-2374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-2387673890dc5c…
2021-03-12 10:30 UTC2021-03A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-235aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-238869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-233f01610625f2…
2019-09-15 20:21 UTC2019-09A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23b00525d2431f…
2019-07-19 19:46 UTC2019-07A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-239b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-233f0d92c62455…
2023-05-13 08:27 UTC2023-05A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23053a50430f4f…
2023-01-26 05:58 UTC2023-01A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-233bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-233a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202828-001ZOLEDRONIC ACIDEQ 5MG BASE/100MLINJECTABLE / INTRAVENOUSAP2013-09-23cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202828-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202828-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202828-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202828-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202828-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202828-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202828-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202828-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202828-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202828-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202828-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202828-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202828-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202828-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202828-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202828-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202828-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202828-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202828-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202828-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202828-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A202828-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202828-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202828-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202828-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A202828-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A202828-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202828-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202828-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202828-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202828-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202828-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202828-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202828-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A202828-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A202828-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202828-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202828-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202828-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202828-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
zoledronic acid
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ZOLEDRONIC ACID.05 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6XC1PAD3KFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
705824Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
164500d7-51cf-438a-8bee-7a7dce76ad7aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
963c7720-927d-e443-b968-0d27f7055a69Product name820240606
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
95fe9bf2-51a5-1324-90da-8451ccf59619Product name920190228
76bb2633-9686-4c41-9e21-c755e223f2e0Product name120160408
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
94acf8b5-886e-4cdd-b38e-791d5af82ba0Product name120150325
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
25021-830-82zoledronic acid100 mL in 1 BAGINJECTION, SOLUTION10021
25021-830-82zoledronic acid1 in 1 CARTONINJECTION, SOLUTION121
25021-830-87zoledronic acid5 in 1 CARTONINJECTION, SOLUTION521
25021-830-87zoledronic acid100 mL in 1 BAGINJECTION, SOLUTION10021

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
25021-830-82ML - Milliliter25021-830e1e9a2b4-5294-4137-ab7f-3260867311a012013-11-04
25021-830-87ML - Milliliter25021-8306b127684-6756-4468-9bc2-2743a99dbbc712025-06-13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
zoledronic acidACTIVE INGREDIENT6XC1PAD3KFZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]14
zoledronic acid anhydrousACTIVE MOIETY70HZ18PH24ZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]14
mannitolINACTIVE INGREDIENT3OWL53L36AZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]14
sodium citrateINACTIVE INGREDIENT1Q73Q2JULRZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]14
waterINACTIVE INGREDIENT059QF0KO0RZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
25021-830ZOLEDRONIC ACID INJECTION, SOLUTION [SAGENT PHARMACEUTICALS]21Current NDC, Legacy NDC, 4 package rows20250325_164500d7-51cf-438a-8bee-7a7dce76ad7a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
zoledronic acidZOLEDRONIC ACIDSagent Pharmaceuticals164500d7-51cf-438a-8bee-7a7dce76ad7a2025-03-11Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202828
application number: ANDA202828
ndc (product): 25021-830

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
705824zoledronic acid 5 MG in 100 ML InjectionPSN164500d7-51cf-438a-8bee-7a7dce76ad7a21
705824100 ML zoledronic acid 0.05 MG/ML InjectionSCD164500d7-51cf-438a-8bee-7a7dce76ad7a21
705824zoledronic acid 5 MG per 100 ML InjectionSY164500d7-51cf-438a-8bee-7a7dce76ad7a21

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
25021-830-82250210830821 BAG in 1 CARTON (25021-830-82) / 100 mL in 1 BAG1 bag2013-03-020000-00-00NoNoCurrent
25021-830-87250210830875 BAG in 1 CARTON (25021-830-87) / 100 mL in 1 BAG5 bag2025-04-15NoNoCurrent