Home NDC 25357-100 iDose TR
Product NDC 25357-100
11-digit product format 253570100
Labeler code 25357
Product ID 25357-100_ea215df6-3744-48fa-a20c-78bf82946bc5
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name Travoprost Intracameral
Dosage form IMPLANT
Route INTRACAMERAL
Labeler Glaukos Corporation
Application NDA218010
Marketing category NDA
Marketing start 2023-12-13
Substance TRAVOPROST
Active strength 75 ug/1
Pharmacologic classes Prostaglandin Analog [EPC], Prostaglandins [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N218010-001 IDOSE TR TRAVOPROST 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13
Orange Book patents# Current patent rows page 1 of 1 · 4 matching rows.
Application-product, Patent, Expiration table Application-product Patent Expiration Use code Coverage / status Submission date N218010-001 12201557 2030-06-18 U-4129 Drug substance, Drug product 2025-02-20 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 N218010-001 12201555 2031-02-14 Drug substance, Drug product 2025-02-20
Orange Book exclusivity# Current exclusivity rows page 1 of 1 · 1 matching rows.
Application-product, Exclusivity code, Expiration table Application-product Exclusivity code Expiration N218010-001 NP 2026-12-13
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-02-19 14:30 UTC 2026-02 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 8072bd15b7f6…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 1c564ffb4f44…2026-07-26 02:55 UTC · 3 captures of this ZIP 2026-06 N218010-001 IDOSE TR 75MCG IMPLANT / INTRACAMERAL RLD, RS 2023-12-13 a50c72e98297…
Observed Orange Book patent history# Patent history page 1 of 2 · 44 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2026-02-19 14:30 UTC 2026-02 N218010-001 12201557 2030-06-18 U-4129 Drug substance, Drug product 2025-02-20 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N218010-001 12201555 2031-02-14 Drug substance, Drug product 2025-02-20 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N218010-001 12201557 2030-06-18 U-4129 Drug substance, Drug product 2025-02-20 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N218010-001 12201555 2031-02-14 Drug substance, Drug product 2025-02-20 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N218010-001 12201557 2030-06-18 U-4129 Drug substance, Drug product 2025-02-20 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N218010-001 12201555 2031-02-14 Drug substance, Drug product 2025-02-20 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N218010-001 12201557 2030-06-18 U-4129 Drug substance, Drug product 2025-02-20 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N218010-001 12201555 2031-02-14 Drug substance, Drug product 2025-02-20 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 d06236e962d9…2024-10-29 15:01 UTC 2024-10 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 79d66fd596c7…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 301d65b070ca…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 1e350fbaab3a…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 8072bd15b7f6…2024-05-31 18:47 UTC 2024-05 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 8072bd15b7f6…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 6a51e52b5d6a…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N218010-001 10206813 2030-10-17 Drug product 2023-12-22 1c564ffb4f44…2024-02-18 07:12 UTC 2024-02 N218010-001 11426306 2030-10-17 Drug product 2023-12-22 1c564ffb4f44…
Observed Orange Book exclusivity history# Additional Listing Data#
Finished product Yes
Brand name base iDose TR
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength TRAVOPROST 75 ug/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination WJ68R08KX9 Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 2672088 Internal RxNorm lookup 2672093 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 25357-100-01 iDose TR 1 in 1 POUCH IMPLANT 1 5 25357-100-01 iDose TR 1 in 1 CARTON IMPLANT 1 5 25357-100-99 iDose TR 1 in 1 POUCH IMPLANT 1 5 25357-100-99 iDose TR 1 in 1 CARTON IMPLANT 1 5
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 25357-100 IDOSE TR (TRAVOPROST INTRACAMERAL) IMPLANT [GLAUKOS CORPORATION] 2 Current NDC, 4 package rows 20231229_92f6d3e2-8328-47df-972c-23008f4a1c1c.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Sample Exclude flag Status 25357-100-01 25357010001 1 POUCH in 1 CARTON (25357-100-01) / 1 TRAY in 1 POUCH / 1 CANISTER in 1 TRAY / 1 IMPLANT in 1 CANISTER 1 pouch 2023-12-13 No No Current 25357-100-99 25357010099 1 POUCH in 1 CARTON (25357-100-99) / 1 TRAY in 1 POUCH / 1 CANISTER in 1 TRAY / 1 IMPLANT in 1 CANISTER 1 pouch 2026-02-17 Yes No Current