Nitrous Oxide

Product NDC: 25543-012
11-digit product format: 255430012
Labeler code: 25543
Product ID: 25543-012_1e8dfa9a-3cc1-4cbe-84c4-12ad149b2027
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Nitrous Oxide
Dosage form: GAS
Route: RESPIRATORY (INHALATION)
Labeler: Airgas East, Inc.
Marketing category: UNAPPROVED MEDICAL GAS
Marketing start: 1991-01-15
Marketing end: 0000-00-00
Substance: NITROUS OXIDE
Active strength: 990 mL/L
NDC exclude flag: E
Listing certified through: 2017-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 10 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	25543-012		I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-01	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-02	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-03	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-04	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-05	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-06	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-07	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-08	I	Inactivated by FDA	2026-08-10
excluded package	package	25543-012	25543-012-09	I	Inactivated by FDA	2026-08-10

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 4 · 220 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-04	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-08	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-06	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-07	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-03	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-09	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	25543-012-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-04	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-08	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-06	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-07	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-03	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-05	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-09	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	25543-012-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-04	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-08	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-06	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-07	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-03	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-09	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	25543-012-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-04	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-08	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-06	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-07	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-03	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-09	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	25543-012-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-04	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-08	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-06	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-07	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-03	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-09	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	25543-012-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-04	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-08	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-06	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-07	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-03	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-09	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	25543-012-02	`cdf11ea48f46…`	`ba0047e9e063…`

FDA-Initiated Inactive NDC Indexing#

NDC, Related label table
NDC	Related label
25543-012-01	nitrous oxide
25543-012-02	nitrous oxide
25543-012-03	nitrous oxide
25543-012-04	nitrous oxide
25543-012-05	nitrous oxide
25543-012-06	nitrous oxide
25543-012-07	nitrous oxide
25543-012-08	nitrous oxide
25543-012-09	nitrous oxide

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
25543-012-01	Nitrous Oxide	368 L in 1 CYLINDER	GAS	368	1
25543-012-02	Nitrous Oxide	934 L in 1 CYLINDER	GAS	934	1
25543-012-03	Nitrous Oxide	1586 L in 1 CYLINDER	GAS	1586	1
25543-012-04	Nitrous Oxide	4927 L in 1 CYLINDER	GAS	4927	1
25543-012-05	Nitrous Oxide	7561 L in 1 CYLINDER	GAS	7561	1
25543-012-06	Nitrous Oxide	13819 L in 1 CYLINDER	GAS	13819	1
25543-012-07	Nitrous Oxide	15801 L in 1 CYLINDER	GAS	15801	1
25543-012-08	Nitrous Oxide	18576 L in 1 CYLINDER	GAS	18576	1
25543-012-09	Nitrous Oxide	95145 L in 1 CYLINDER	GAS	95145	1

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version	Uploaded
Nitrous Oxide	ACTIVE INGREDIENT	K50XQU1029	NITROUS OXIDE GAS [AIRGAS EAST, INC.]	1
Nitrous Oxide	ACTIVE MOIETY	K50XQU1029	NITROUS OXIDE GAS [AIRGAS EAST, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
25543-012	NITROUS OXIDE GAS [AIRGAS EAST, INC.]	1	Legacy NDC, 9 package rows	20100811_9a5fd48e-41bd-4aad-9ca6-aa8e640d9d27.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
K50XQU1029	NITROUS OXIDE	10024-97-2	NITROUS OXIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
312022	nitrous oxide 99 % Gas for Inhalation	PSN	9a5fd48e-41bd-4aad-9ca6-aa8e640d9d27	1
312022	nitrous oxide 99 % Gas for Inhalation	SCD	9a5fd48e-41bd-4aad-9ca6-aa8e640d9d27	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
25543-012-01	25543001201	368 L in 1 CYLINDER	368 l	Historical
25543-012-02	25543001202	934 L in 1 CYLINDER	934 l	Historical
25543-012-03	25543001203	1586 L in 1 CYLINDER	1586 l	Historical
25543-012-04	25543001204	4927 L in 1 CYLINDER	4927 l	Historical
25543-012-05	25543001205	7561 L in 1 CYLINDER	7561 l	Historical
25543-012-06	25543001206	13819 L in 1 CYLINDER	13819 l	Historical
25543-012-07	25543001207	15801 L in 1 CYLINDER	15801 l	Historical
25543-012-08	25543001208	18576 L in 1 CYLINDER	18576 l	Historical
25543-012-09	25543001209	95145 L in 1 CYLINDER	95145 l	Historical