Methadone Hydrochloride

Product NDC
31722-947
11-digit product format
317220947
Labeler code
31722
Product ID
31722-947_24878a39-232d-45f6-af1f-fbb00eb5d915
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methadone Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Camber Pharmaceuticals, Inc
Application
ANDA211228
Marketing category
ANDA
Marketing start
2019-01-03
Substance
METHADONE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211228-001METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03
A211228-002METHADONE HYDROCHLORIDEMETHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A211228-001AA
A211228-002AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-035bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03d06236e962d9…
2024-10-29 15:01 UTC2024-10A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-0379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-031e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-038072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-035c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-035d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-034b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-0374a2ff9319b5…
2019-12-13 00:20 UTC2019-12A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211228-001METHADONE HYDROCHLORIDE5MGTABLET / ORALAA2019-01-03782e0a99824c…
2021-12-28 21:50 UTC2021-12A211228-002METHADONE HYDROCHLORIDE10MGTABLET / ORALAA2019-01-03782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A211228-001AA1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211228-002AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211228-001AA131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211228-002AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211228-001AA16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211228-002AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211228-001AA1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211228-002AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211228-001AA1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211228-002AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211228-001AA103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211228-002AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211228-001AA12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211228-002AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211228-001AA15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211228-002AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211228-001AA1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211228-002AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211228-001AA1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211228-002AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211228-001AA179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211228-002AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211228-001AA1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211228-002AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211228-001AA11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211228-002AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211228-001AA18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211228-002AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211228-001AA15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211228-002AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211228-001AA15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A211228-002AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211228-001AA14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A211228-002AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211228-001AA174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A211228-002AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211228-001AA1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A211228-002AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211228-001AA1782e0a99824c…
2021-12-28 21:50 UTC2021-12A211228-002AA1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Methadone Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHADONE HYDROCHLORIDE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
229809935BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
864706Internal RxNorm lookup
864718Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8f4cf84e-165c-489d-a668-0f715053f196Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bc6c52c8-e3e2-9042-21d0-6770dcf1a49bProduct name320250819
a48f0261-b6cc-12b3-49fd-ed131bc5aa96Product name420210902
00dcb24c-d95e-78f6-6c1b-4d7b709bb2b9Product name620200708
a6a96832-f31d-b458-45cb-abb8bd940b44Product name220200304

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
31722-947-01Methadone Hydrochloride100 in 1 BOTTLETABLET1007

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
31722-947-01EA - Each31722-9479c8114ce-3c83-4706-978c-4e7457532bea12019-06-19

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
31722-947METHADONE HYDROCHLORIDE TABLET [CAMBER PHARMACEUTICALS, INC]6Current NDC, Legacy NDC, 1 package rows20240418_8f4cf84e-165c-489d-a668-0f715053f196.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methadone HydrochlorideMETHADONE HYDROCHLORIDEAmerican Health Packaging540edd43-165d-4257-b989-3bccc8f54afb2026-08-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211228
application number: ANDA211228
Methadone HydrochlorideMETHADONE HYDROCHLORIDECamber Pharmaceuticals, Inc8f4cf84e-165c-489d-a668-0f715053f1962025-08-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211228
application number: ANDA211228
ndc (product): 31722-947
Methadone HydrochlorideMETHADONE HYDROCHLORIDEXLCare Pharmaceuticals, Inc1a536622-dda3-41af-ab08-28e7c1bc93002024-01-11Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211228
application number: ANDA211228

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
864706methadone HCl 10 MG Oral TabletPSN8f4cf84e-165c-489d-a668-0f715053f1967
864718methadone HCl 5 MG Oral TabletPSN8f4cf84e-165c-489d-a668-0f715053f1967
864706methadone hydrochloride 10 MG Oral TabletSCD8f4cf84e-165c-489d-a668-0f715053f1967
864718methadone hydrochloride 5 MG Oral TabletSCD8f4cf84e-165c-489d-a668-0f715053f1967

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
31722-947-0131722094701100 TABLET in 1 BOTTLE (31722-947-01) 100 tablet2019-01-030000-00-00NoNoCurrent