Methimazole

Product NDC
33342-335
11-digit product format
333420335
Labeler code
33342
Product ID
33342-335_ea518c56-49d7-4770-8ded-21e443e71c3c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methimazole
Dosage form
TABLET
Route
ORAL
Labeler
Macleods Pharmaceuticals Limited
Application
ANDA209827
Marketing category
ANDA
Marketing start
2023-05-24
Substance
METHIMAZOLE
Active strength
5 mg/1
Pharmacologic classes
Thyroid Hormone Synthesis Inhibitor [EPC], Thyroid Hormone Synthesis Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A209827-001METHIMAZOLEMETHIMAZOLE5MGTABLET / ORALAB2023-05-24
A209827-002METHIMAZOLEMETHIMAZOLE10MGTABLET / ORALAB2023-05-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A209827-001AB
A209827-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 44 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24d06236e962d9…
2024-10-29 15:01 UTC2024-10A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-241e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-248072bd15b7f6…
2024-05-31 18:47 UTC2024-05A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-248072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-246a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-241c564ffb4f44…
2024-02-18 07:12 UTC2024-02A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-249b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209827-001METHIMAZOLE5MGTABLET / ORALAB2023-05-24a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209827-002METHIMAZOLE10MGTABLET / ORALAB2023-05-24a67488948f0b…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 44 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A209827-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A209827-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209827-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209827-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A209827-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A209827-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209827-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209827-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209827-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209827-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209827-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209827-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209827-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209827-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209827-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209827-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209827-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209827-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209827-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A209827-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209827-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209827-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209827-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209827-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209827-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209827-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A209827-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A209827-002AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209827-001AB16a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209827-002AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A209827-001AB11c564ffb4f44…
2024-02-18 07:12 UTC2024-02A209827-002AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A209827-001AB1ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12A209827-002AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209827-001AB1a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209827-002AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209827-001AB19b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209827-002AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209827-001AB1a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209827-002AB1a67488948f0b…

Additional Listing Data#

Finished product
Yes
Brand name base
Methimazole
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHIMAZOLE5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
554Z48XN5EInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197941Internal RxNorm lookup
197942Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6f08df05-cc29-45ef-8f6e-12272bfbb0d7Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
42f09d00-d445-e29e-bea8-dfb46b9366fcProduct name420251118

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
33342-335-11Methimazole100 in 1 BOTTLETABLET1003
33342-335-12Methimazole10 in 1 CARTONTABLET103
33342-335-12Methimazole10 in 1 BLISTER PACKTABLET103
33342-335-44Methimazole1000 in 1 BOTTLETABLET10003

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
33342-335METHIMAZOLE TABLET [MACLEODS PHARMACEUTICALS LIMITED]2Current NDC, 4 package rows20230910_6f08df05-cc29-45ef-8f6e-12272bfbb0d7.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MethimazoleMETHIMAZOLEMacleods Pharmaceuticals Limited6f08df05-cc29-45ef-8f6e-12272bfbb0d72025-09-25Warnings, Adverse reactionsExact identifier
application applno (ANDA): 209827
application number: ANDA209827
ndc (product): 33342-335

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197941methIMAzole 10 MG Oral TabletPSN6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197942methIMAzole 5 MG Oral TabletPSN6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197941methimazole 10 MG Oral TabletSCD6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197942methimazole 5 MG Oral TabletSCD6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197941thiamazole 10 MG Oral TabletSY6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197942thiamazole 5 MG Oral TabletSY6f08df05-cc29-45ef-8f6e-12272bfbb0d73
197942methIMAzole 5 MG Oral TabletPSNdf9749eb-6f90-49c1-8357-83e30f2b9bc61
197942methimazole 5 MG Oral TabletSCDdf9749eb-6f90-49c1-8357-83e30f2b9bc61
197942thiamazole 5 MG Oral TabletSYdf9749eb-6f90-49c1-8357-83e30f2b9bc61

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
33342-335-1133342033511100 TABLET in 1 BOTTLE (33342-335-11) 100 tablet2023-05-24NoNoCurrent
33342-335-123334203351210 BLISTER PACK in 1 CARTON (33342-335-12) / 10 TABLET in 1 BLISTER PACK10 blister pack2023-05-24NoNoCurrent
33342-335-44333420335441000 TABLET in 1 BOTTLE (33342-335-44) 1000 tablet2023-05-24NoNoCurrent