Desvenlafaxine Succinate

Product NDC
33342-388
11-digit product format
333420388
Labeler code
33342
Product ID
33342-388_edf18b33-a226-44f8-9f42-c409e691ee64
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Desvenlafaxine Succinate
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
Macleods Pharmaceuticals Limited
Application
ANDA211427
Marketing category
ANDA
Marketing start
2020-07-30
Substance
DESVENLAFAXINE SUCCINATE
Active strength
50 mg/1
Pharmacologic classes
Cytochrome P450 2D6 Inhibitors [MoA], Norepinephrine Uptake Inhibitors [MoA], Serotonin Uptake Inhibitors [MoA], Serotonin and Norepinephrine Reuptake Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211427-001DESVENLAFAXINE SUCCINATEDESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15
A211427-002DESVENLAFAXINE SUCCINATEDESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A211427-001AB
A211427-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15caaa826d4ba7…
2026-08-18 06:07:402026-07A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211427-001DESVENLAFAXINE SUCCINATEEQ 50MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211427-002DESVENLAFAXINE SUCCINATEEQ 100MG BASETABLET, EXTENDED RELEASE / ORALAB2025-01-15a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211427-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A211427-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211427-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211427-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211427-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211427-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211427-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211427-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211427-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211427-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211427-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211427-002AB1b8a1b40f171c…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211427-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211427-002AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Desvenlafaxine Succinate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DESVENLAFAXINE SUCCINATE50 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ZB22ENF0XRInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1874553Internal RxNorm lookup
1874559Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
edf18b33-a226-44f8-9f42-c409e691ee64Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a9aae381-3b13-08a9-c49d-484a2c2a6dc8Product name720251106
99b326f2-4886-9fc8-8686-faef7b7f27ddProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
33342-388-07Desvenlafaxine Succinate30 in 1 BOTTLETABLET, EXTENDED RELEASE301
33342-388-10Desvenlafaxine Succinate90 in 1 BOTTLETABLET, EXTENDED RELEASE901
33342-388-12Desvenlafaxine Succinate10 in 1 BLISTER PACKTABLET, EXTENDED RELEASE101
33342-388-12Desvenlafaxine Succinate10 in 1 CARTONTABLET, EXTENDED RELEASE101

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
33342-388-07EA - Each33342-3887feca922-a754-4877-8e66-8848fbabef6412025-10-14
33342-388-10EA - Each33342-388bcc9bb6c-3990-4ce5-b504-b51e7fe04ebc12025-10-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
33342-388DESVENLAFAXINE SUCCINATE TABLET, EXTENDED RELEASE [MACLEODS PHARMACEUTICALS LIMITED]1Current NDC, 4 package rows20250412_edf18b33-a226-44f8-9f42-c409e691ee64.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Desvenlafaxine SuccinateDESVENLAFAXINE SUCCINATEMacleods Pharmaceuticals Limitededf18b33-a226-44f8-9f42-c409e691ee642024-08-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211427
application number: ANDA211427
ndc (product): 33342-388

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1874553desvenlafaxine succinate 100 MG 24HR Extended Release Oral TabletPSNedf18b33-a226-44f8-9f42-c409e691ee641
1874559desvenlafaxine succinate 50 MG 24HR Extended Release Oral TabletPSNedf18b33-a226-44f8-9f42-c409e691ee641
187455324 HR desvenlafaxine succinate 100 MG Extended Release Oral TabletSCDedf18b33-a226-44f8-9f42-c409e691ee641
187455924 HR desvenlafaxine succinate 50 MG Extended Release Oral TabletSCDedf18b33-a226-44f8-9f42-c409e691ee641
1874553desvenlafaxine 100 MG (as desvenlafaxine succinate 152 MG) 24HR Extended Release Oral TabletSYedf18b33-a226-44f8-9f42-c409e691ee641
1874559desvenlafaxine 50 MG (as desvenlafaxine succinate 76 MG) 24HR Extended Release Oral TabletSYedf18b33-a226-44f8-9f42-c409e691ee641

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
33342-388-073334203880730 TABLET, EXTENDED RELEASE in 1 BOTTLE (33342-388-07) 2020-07-30NoNoCurrent
33342-388-103334203881090 TABLET, EXTENDED RELEASE in 1 BOTTLE (33342-388-10) 2020-07-30NoNoCurrent
33342-388-123334203881210 BLISTER PACK in 1 CARTON (33342-388-12) / 10 TABLET, EXTENDED RELEASE in 1 BLISTER PACK10 blister pack2020-07-30NoNoCurrent