topcare anti diarrheal anti gas

Product NDC
36800-633
11-digit product format
368000633
Labeler code
36800
Product ID
36800-633_0bd10a98-0d1c-4ae7-b758-25916d54fae1
Type
HUMAN OTC DRUG
Nonproprietary name
loperamide hydrochloride, simethicone
Dosage form
TABLET
Route
ORAL
Labeler
Topco Associates LLC
Application
ANDA209837
Marketing category
ANDA
Marketing start
2018-10-09
Marketing end
0000-00-00
Substance
LOPERAMIDE HYDROCHLORIDE; DIMETHICONE
Active strength
2 mg/1; mg/1
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct36800-633IInactivated by FDA2026-08-03
excluded packagepackage36800-63336800-633-53IInactivated by FDA2026-08-03
excluded packagepackage36800-63336800-633-62IInactivated by FDA2026-08-03
excluded packagepackage36800-63336800-633-65DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONELOPERAMIDE HYDROCHLORIDE; SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-0587673890dc5c…
2021-03-12 10:30 UTC2021-03A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-053f01610625f2…
2019-09-15 20:21 UTC2019-09A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05b00525d2431f…
2019-07-19 19:46 UTC2019-07A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-053f0d92c62455…
2023-05-13 08:27 UTC2023-05A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05053a50430f4f…
2023-01-26 05:58 UTC2023-01A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A209837-001LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE2MG;125MGTABLET / ORAL2018-09-05cb3db0bc1861…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
10f838ef-a72b-645d-80f8-e2255205c3b1Product name620240805

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
36800-633-53topcare anti diarrheal anti gas1 in 1 BLISTER PACKTABLET15
36800-633-53topcare anti diarrheal anti gas12 in 1 CARTONTABLET125
36800-633-62topcare anti diarrheal anti gas1 in 1 BLISTER PACKTABLET15
36800-633-62topcare anti diarrheal anti gas24 in 1 CARTONTABLET245
36800-633-65topcare anti diarrheal anti gas30 in 1 BOTTLETABLET305
36800-633-65topcare anti diarrheal anti gas1 in 1 CARTONTABLET15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
36800-633TOPCARE ANTI DIARRHEAL ANTI GAS (LOPERAMIDE HYDROCHLORIDE, SIMETHICONE) TABLET [TOPCO ASSOCIATES LLC]5Legacy NDC, 6 package rows20240724_7ada1c47-8d4f-4742-9b6d-aa2766119532.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 17 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
good sense anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEL. Perrigo Company2cda08a8-3f5e-430c-84a3-d29b97d647af2026-05-20WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
CareOne Diarrhea and Gas ControlLOPERAMIDE HYDROCHLORIDE, SIMETHICONEAmerican Sales Companydfa3db5a-cef6-4ed5-b9f1-a20b6d1657b32026-04-21WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEHyVee Inc396ea4f5-5c3d-4cbc-acd5-09eb64c806e02026-03-02WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEH E B35cff261-932e-4b2e-ab21-80969c27fa922025-06-27WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
good neighbor pharmacy anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEAmerisource Bergen5dae1247-3ec0-495e-b3f2-1c15551416172025-04-08WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
Anti Diarrheal Anti GasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEKroger Company9c7db942-c8cb-493a-a96f-452b8dfebfc62024-07-23WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
signature care anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONESafeway53829e72-d22c-434d-a108-1972081a6efb2024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal and anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEWalgreen Company0999243a-c3be-41a6-b327-962e63d8c3562024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
dg health anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEDolgencorp, LLC09798231-39cd-49b2-9be5-ea51e52f0a6d2024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
Basic Care Loperamide Hydrochloride and SimethiconeLOPERAMIDE HYDROCHLORIDE, SIMETHICONEAmazon.com Services LLCaa79234e-1fbd-4279-b4b1-46b4f041b4e82024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
equaline anti diarrheal plus anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEUnited Natural Foods, Inc. dba UNFI2ce0b37e-6dc4-423f-a1d6-a2cb623946d52024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
up and up anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONETarget Corporationef75085c-95df-4901-9c97-069fcfc3eef72024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONERite Aid Corporation8e954f86-bc15-45e2-9274-ca5d8a7c96872024-07-22WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal and anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONECVS Pharmacy065699b5-217e-432f-a253-cea2d3f622332024-07-20WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
Good Sense Anti Diarrheal Anti GasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEL. Perrigo Companyfcfd0b64-6876-4e6f-8a7b-ca1da9e03f002024-07-13WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
anti diarrheal plus anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEMeijer Distribution Ince2c9a752-618a-4e34-89a5-671aab4013ac2024-07-11WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837
foster and thrive anti diarrheal anti gasLOPERAMIDE HYDROCHLORIDE, SIMETHICONEStrategic Sourcing Services LLC9132dc1c-8e16-4236-881e-863f5e57f0ab2024-07-08WarningsExact identifier
application applno (ANDA): 209837
application number: ANDA209837

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
978001loperamide HCl 2 MG / simethicone 125 MG Oral TabletPSN7ada1c47-8d4f-4742-9b6d-aa27661195325
978001loperamide hydrochloride 2 MG / simethicone 125 MG Oral TabletSCD7ada1c47-8d4f-4742-9b6d-aa27661195325

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
36800-633-533680006335312 BLISTER PACK in 1 CARTON (36800-633-53) > 1 TABLET in 1 BLISTER PACK12 blister pack2018-10-090000-00-00NoNoCurrent
36800-633-623680006336224 BLISTER PACK in 1 CARTON (36800-633-62) > 1 TABLET in 1 BLISTER PACK24 blister pack2020-06-050000-00-00NoNoCurrent
36800-633-65368000633651 BOTTLE in 1 CARTON (36800-633-65) > 30 TABLET in 1 BOTTLE1 bottle2018-10-090000-00-00NoNoCurrent