Head and Shoulders 2in1

Product NDC
37000-070
11-digit product format
370000070
Labeler code
37000
Product ID
37000-070_4cda6862-9f21-b990-e063-6294a90a5813
Type
HUMAN OTC DRUG
Nonproprietary name
Pyrithione Zinc
Dosage form
LOTION/SHAMPOO
Route
TOPICAL
Labeler
The Procter & Gamble Manufacturing Company
Application
M032
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2013-09-01
Substance
PYRITHIONE ZINC
Active strength
1 g/100mL
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage37000-07037000-070-10DDiscontinued by firm2026-10-12
excluded packagepackage37000-07037000-070-12DDiscontinued by firm2026-10-12
excluded packagepackage37000-07037000-070-40DDiscontinued by firm2026-10-12
excluded packagepackage37000-07037000-070-70DDiscontinued by firm2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 54 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source datePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-0537000-070-95d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-0537000-070-10d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-0537000-070-12d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-0537000-070-40d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-0537000-070-70d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-2637000-070-95f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-2637000-070-10f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-2637000-070-12f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-2637000-070-40f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-2637000-070-70f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-3137000-070-952ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-3137000-070-102ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-3137000-070-122ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-3137000-070-402ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-3137000-070-702ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-2837000-070-95a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-2837000-070-10a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-2837000-070-12a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-2837000-070-40a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-2837000-070-70a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-2137000-070-95cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-2137000-070-10cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-2137000-070-12cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-2137000-070-40cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-2137000-070-70cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-1037000-070-95cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-1037000-070-10cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-1037000-070-12cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-1037000-070-40cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-1037000-070-70cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-3137000-070-95302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-3137000-070-10302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-3137000-070-12302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-3137000-070-40302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-3137000-070-70302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-2037000-070-95ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-2037000-070-10ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-2037000-070-12ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-2037000-070-40ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-2037000-070-70ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-1037000-070-950efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-1037000-070-100efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-1037000-070-120efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-1037000-070-400efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-1037000-070-700efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-0837000-070-10ad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-0837000-070-40ad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-0837000-070-70ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-0337000-070-10367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-0337000-070-70367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-0337000-070-40367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-0937000-070-10557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-0937000-070-70557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-0937000-070-40557ba5c1ecfa…9c80585c8c6e…

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product
Yes
Brand name base
Head and Shoulders 2in1
Brand name suffix
Classic Clean
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PYRITHIONE ZINC1 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
R953O2RHZ5Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
209884Internal RxNorm lookup
1043244Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
65a4082f-227b-49bf-b88c-b1c651ed13a0Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
37000-070-01Head and Shoulders 2in1Classic Clean2 in 1 CELLO PACKLOTION/SHAMPOO211
37000-070-01Head and Shoulders 2in1Classic Clean950 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO95011
37000-070-10Head and Shoulders 2in1Classic Clean1000 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO100011
37000-070-12Head and Shoulders 2in1Classic Clean1280 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO128011
37000-070-25Head and Shoulders 2in1Classic Clean250 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO25011
37000-070-37Head and Shoulders 2in1Classic Clean370 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO37011
37000-070-40Head and Shoulders 2in1Classic Clean400 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO40011
37000-070-61Head and Shoulders 2in1Classic Clean613 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO61311
37000-070-70Head and Shoulders 2in1Classic Clean700 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO70011
37000-070-83Head and Shoulders 2in1Classic Clean835 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO83511
37000-070-95Head and Shoulders 2in1Classic Clean950 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO95011

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
Pyrithione ZincACTIVE INGREDIENTR953O2RHZ5HEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
Pyrithione ZincACTIVE MOIETYR953O2RHZ5HEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
cocamidopropyl betaineINACTIVE INGREDIENT5OCF3O11KXHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
D&C red no. 33INACTIVE INGREDIENT9DBA0SBB0LHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
dimethiconeINACTIVE INGREDIENT92RU3N3Y1OHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
FD&C blue no. 1INACTIVE INGREDIENTH3R47K3TBDHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
glycol distearateINACTIVE INGREDIENT13W7MDN21WHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
magnesium carbonate hydroxideINACTIVE INGREDIENTYQO029V1L4HEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
methylchloroisothiazolinoneINACTIVE INGREDIENTDEL7T5QRPNHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
methylisothiazolinoneINACTIVE INGREDIENT229D0E1QFAHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
sodium benzoateINACTIVE INGREDIENTOJ245FE5EUHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
sodium chlorideINACTIVE INGREDIENT451W47IQ8XHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
sodium laureth-3 sulfateINACTIVE INGREDIENTBPV390UAP0HEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
sodium lauryl sulfateINACTIVE INGREDIENT368GB5141JHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
sodium xylenesulfonateINACTIVE INGREDIENTG4LZF950URHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
waterINACTIVE INGREDIENT059QF0KO0RHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1
zinc carbonateINACTIVE INGREDIENTEQR32Y7H0MHEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
37000-070HEAD AND SHOULDERS 2IN1 CLASSIC CLEAN (PYRITHIONE ZINC) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]10Current NDC, Legacy NDC, 11 package rows20241030_65a4082f-227b-49bf-b88c-b1c651ed13a0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 6 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Dove Men CareANTI-DANDRUFF 2IN1 SHAMPOO AND CONDITIONERConopco d/b/a Unilever4ecce67b-b2e0-b757-e063-6294a90a224e2026-04-07WarningsExact identifier
application number: M032
Dove Men CareANTI-DANDRUFF DRYNESS AND ITCH RELIEF 2 IN 1 SHAMPOO AND CONDITONERConopco d/b/a Unilever4edfa86c-0139-5bc5-e063-6294a90a5d732026-04-07WarningsExact identifier
application number: M032
DoveSOOTHING MOISTURE DAMAGE THERAPY ANTI-DANDRUFF SHAMPOOConopco d/b/a Unilever4ecb2eac-0d1c-b59d-e063-6394a90a49e32026-04-06WarningsExact identifier
application number: M032
Happy Head Anti-DandruffPYRITHIONE ZINCHappy Head, Incf0d5daea-72fc-4e40-a390-9da42cadbe3a2026-04-06WarningsExact identifier
application number: M032
DoveCALMING RELIEF DAMAGE THERAPY ANTI-DANDRUFF 2 IN 1 SHAMPOO AND CONDITIONERConopco d/b/a Unilever4ecc1232-065f-c63e-e063-6394a90ac63b2026-04-06WarningsExact identifier
application number: M032
Suave Professionals Men 2 in 1 Classic Clean AntiDandruffPYRITHIONE ZINCConopco Inc. d/b/a Unileverd85e52e5-c3e2-4be0-aa3f-3511a69ecc4f2026-04-03WarningsExact identifier
application number: M032
Denorex Multi-Symptom Anti-DandruffSALICYLIC ACIDNeoteric Cosmetics, Inc.4e904a6b-a732-558b-e063-6294a90ac6422026-04-01WarningsExact identifier
application number: M032
Denorex Extra StrengthSALICYLIC ACIDNeoteric Cosmetics, Inc.21d234ff-f379-4bcd-9ba0-90f27c6d3a692026-04-01WarningsExact identifier
application number: M032
EASYES ANTI DANDRUFF AND ANTI HAIR THINNING SHAMP00EASYES ANTI DANDRUFF AND ANTI HAIR THINNING SHAMP00Qingyuan Moksha Biotechnology Co., Ltd.4e386cc8-004a-9742-e063-6394a90a763c2026-03-30WarningsExact identifier
application number: M032
Tio Nacho Anti-DandruffSALICYLIC ACIDGenomma Lab USAc3c92b35-4955-4985-9a1d-8756c1b2131c2026-03-27WarningsExact identifier
application number: M032
Suave Antidandruff 2 IN 1 Classic CleanANTI DANDRUFF 2N1 SHAMPOO AND CONDITIONERSuave Brands Co., LLC41d9cfec-6d14-f620-e063-6294a90a078d2026-03-26WarningsExact identifier
application number: M032
Suave Anti dandruff Coconut MoistureANTI DANDRUFF SHAMPOOSuave Brands Co., LLC41da3d90-4845-0d8f-e063-6294a90aede12026-03-26WarningsExact identifier
application number: M032
Suave Men 2 IN1 Scalp DefenseANTI DANDRUFF SHAMPOO AND CONDITIONERSuave Brands Co., LLC42517082-4d0a-90a3-e063-6294a90a59272026-03-26WarningsExact identifier
application number: M032
Suave Men Antidandruff 2 IN 1 Classic CleanANTI DANDRUFF SHAMPOO AND CONDITIONERSuave Brands Co., LLC425264b9-62a9-fd7b-e063-6294a90a37a22026-03-26WarningsExact identifier
application number: M032
Pyrithione ZincPYRITHIONE ZINCNice-Pak Products, LLC4db2aaf4-5caf-d9e5-e063-6294a90aa4ea2026-03-23Warnings, Adverse reactionsExact identifier
application number: M032
MG217 Psoriasis Medicated multi-symptomCOAL TARWisconsin Pharmacal Company7cb04d20-9b3c-27bb-e053-2a91aa0a5bc42026-03-20WarningsExact identifier
application number: M032
MG217 Psoriasis Therapeutic ConditionerSALICYLIC ACIDWisconsin Pharmacal Company246f239f-16fb-24b2-e054-00144ff8d46c2026-03-20WarningsExact identifier
application number: M032
Dermeleve Scalp Psoriasis TreatmentSALICYLIC ACIDAdvanced Derm Solutions LLCf55da7a8-0a26-4925-bd3b-fade6156116d2026-03-19WarningsExact identifier
application number: M032
Head and Shoulders Smooth and Silky KitPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company4d38902f-a6ae-620f-e063-6394a90ae9322026-03-17WarningsExact identifier
application number: M032
RoyceDerm Seborrheic Dermatitis and Psoriasis Shampoo.SALICYLIC ACID 3%RoyceDerm LLC4d2f6e29-5d75-6982-e063-6294a90ada8d2026-03-16WarningsExact identifier
application number: M032

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1043244head & shoulders 1 % Medicated ShampooPSN65a4082f-227b-49bf-b88c-b1c651ed13a011
209884zinc pyrithione 1 % Medicated ShampooPSN65a4082f-227b-49bf-b88c-b1c651ed13a011
1043244zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]SBD65a4082f-227b-49bf-b88c-b1c651ed13a011
209884zinc pyrithione 10 MG/ML Medicated ShampooSCD65a4082f-227b-49bf-b88c-b1c651ed13a011
1043244Head & Shoulders 1 % Medicated ShampooSY65a4082f-227b-49bf-b88c-b1c651ed13a011
1043244Head & Shoulders 10 MG/ML Medicated ShampooSY65a4082f-227b-49bf-b88c-b1c651ed13a011
209884zinc pyrithione 1 % Medicated ConditionerSY65a4082f-227b-49bf-b88c-b1c651ed13a011
209884zinc pyrithione 1 % Medicated ShampooSY65a4082f-227b-49bf-b88c-b1c651ed13a011

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
37000-070-01370000070012 BOTTLE, PUMP in 1 CELLO PACK (37000-070-01) / 950 mL in 1 BOTTLE, PUMP2022-01-01NoNoCurrent
37000-070-10370000070101000 mL in 1 BOTTLE, PUMP1000 mlHistorical
37000-070-12370000070121280 mL in 1 BOTTLE, PUMP (37000-070-12) 1280 ml2020-01-150000-00-00NoNoCurrent
37000-070-2537000007025250 mL in 1 BOTTLE, PUMP (37000-070-25) 250 ml2013-09-010000-00-00NoNoCurrent
37000-070-3737000007037370 mL in 1 BOTTLE, PLASTIC (37000-070-37) 370 ml2022-11-15NoNoCurrent
37000-070-4037000007040400 mL in 1 BOTTLE, PUMP (37000-070-40) 400 ml2013-09-010000-00-00NoNoCurrent
37000-070-6137000007061613 mL in 1 BOTTLE, PLASTIC (37000-070-61) 613 ml2022-11-15NoNoCurrent
37000-070-7037000007070700 mL in 1 BOTTLE, PLASTIC (37000-070-70) 700 ml2013-09-010000-00-00NoNoCurrent
37000-070-8337000007083835 mL in 1 BOTTLE, PUMP (37000-070-83) 835 ml2022-11-15NoNoCurrent
37000-070-9537000007095950 mL in 1 BOTTLE, PUMP (37000-070-95) 950 ml2016-11-100000-00-00NoNoCurrent