Crest Pro-Health Multi-Protection

Product NDC
37000-451
11-digit product format
370000451
Labeler code
37000
Product ID
37000-451_47e4e758-d6de-4e88-e063-6394a90ac40e
Type
HUMAN OTC DRUG
Nonproprietary name
Cetylpyridinium chloride
Dosage form
RINSE
Route
ORAL
Labeler
The Procter & Gamble Manufacturing Company
Application
M022
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2011-02-03
Substance
CETYLPYRIDINIUM CHLORIDE
Active strength
.014 g/20mL
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage37000-45137000-451-10DDiscontinued by firm2026-09-09

Additional Listing Data#

Finished product
Yes
Brand name base
Crest Pro-Health Multi-Protection
Brand name suffix
Refreshing Clean Mint
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CETYLPYRIDINIUM CHLORIDE.014 g/20mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
D9OM4SK49PInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1100924Internal RxNorm lookup
1251371Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8867d791-7e93-4f39-aaaf-bfbee8296fd9Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDCEffectiveRelated label
37000-451-012023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-022023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-022023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102023-05-19Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-022023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-022023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102023-01-30Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102021-02-12Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-012021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-032021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-042021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-052021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-062021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint
37000-451-102021-01-29Crest ® Pro-Health ® Multi-Protection Clean Mint

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
37000-451-01Crest Pro-Health Multi-ProtectionRefreshing Clean Mint36 mL in 1 BOTTLE, PLASTICRINSE3614
37000-451-02Crest Pro-Health Multi-ProtectionRefreshing Clean Mint100 mL in 1 BOTTLE, PLASTICRINSE10014
37000-451-03Crest Pro-Health Multi-ProtectionRefreshing Clean Mint250 mL in 1 BOTTLE, PLASTICRINSE25014
37000-451-04Crest Pro-Health Multi-ProtectionRefreshing Clean Mint500 mL in 1 BOTTLE, PLASTICRINSE50014
37000-451-05Crest Pro-Health Multi-ProtectionRefreshing Clean Mint1000 mL in 1 BOTTLE, PLASTICRINSE100014
37000-451-06Crest Pro-Health Multi-ProtectionRefreshing Clean Mint1500 mL in 1 BOTTLE, PLASTICRINSE150014
37000-451-10Crest Pro-Health Multi-ProtectionRefreshing Clean Mint2 in 1 PACKAGERINSE214
37000-451-10Crest Pro-Health Multi-ProtectionRefreshing Clean Mint1000 mL in 1 BOTTLERINSE100014
37000-451-11Crest Pro-Health Multi-ProtectionRefreshing Clean Mint3 in 1 CELLO PACKRINSE314
37000-451-11Crest Pro-Health Multi-ProtectionRefreshing Clean Mint1000 mL in 1 BOTTLE, PLASTICRINSE100014

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
Cetylpyridinium chlorideACTIVE INGREDIENTD9OM4SK49PCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
CetylpyridiniumACTIVE MOIETYCUB7JI0JV3CREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
FD&C blue no. 1INACTIVE INGREDIENTH3R47K3TBDCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
glycerinINACTIVE INGREDIENTPDC6A3C0OXCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
methylparabenINACTIVE INGREDIENTA2I8C7HI9TCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
poloxamer 407INACTIVE INGREDIENTTUF2IVW3M2CREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
propylparabenINACTIVE INGREDIENTZ8IX2SC1OHCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
saccharin sodium dihydrateINACTIVE INGREDIENTSB8ZUX40TYCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1
waterINACTIVE INGREDIENT059QF0KO0RCREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [PROCTER & GAMBLE MANUFACTURING COMPANY]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
37000-451CREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [THE PROCTER & GAMBLE MANUFACTURING COMPANY]11Current NDC, Legacy NDC, 10 package rows20250309_8867d791-7e93-4f39-aaaf-bfbee8296fd9.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 42 · 822 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SalineSALINE NASAL SPRAYDynarex Corporation3247ae7d-554f-baab-e063-6294a90aa3ec2026-08-25WarningsExact identifier
application number: M022
AntisepticEUCALYPTOL, MENTHOL, METHYL SALICYLATE, THYMOLWALMART INC. (see also Equate)584b38ce-d1ef-4ecc-a887-7c96e7f9669f2026-08-20WarningsExact identifier
application number: M022
AntisepticEUCALYPTOL, MENTHOL, METHYL SALICYLATE, THYMOLWalgreensfb93c7f6-e025-4cf2-9997-acfe9a0debdd2026-08-19WarningsExact identifier
application number: M022
CVS SalineNASALCVS PHARMACYf02c41b0-c78e-41cd-aa4a-2756bbe920872026-08-19WarningsExact identifier
application number: M022
Ludens Honey Licorice Throat DropsMENTHOLPrestige Brands Holdings, Inc.5dc2baec-a9ed-4f6b-a7ed-76a5d35739ac2026-08-19WarningsExact identifier
application number: M022
Ludens Dual ReliefPECTIN AND MENTHOLPrestige Brands Holdings, Inc.d0213cb3-ec8e-40cc-82c9-694032f0490f2026-08-19WarningsExact identifier
application number: M022
CVS Health Sore Throat Fast Relief Oral AnestheticPHENOLCVS Pharmacy,Inc.4fb880db-2185-41ef-a5f9-8983a28d2c5b2026-08-17WarningsExact identifier
application number: M022
CVS Sore Throat CherryPHENOLCVS Pharmacy,Inc.887c68e0-ff44-4bad-b360-56fb99ed9c452026-08-17WarningsExact identifier
application number: M022
CVS Sore Throat Menthol FlavorPHENOLCVS PHARMACY,INC.665be058-b965-4b78-80b0-dd85241809322026-08-17WarningsExact identifier
application number: M022
Hydrogen Peroxide 3 PercentHYDROGEN PEROXIDEHarris Teeter, LLC7e5f175d-f0d6-4665-ac14-1873d6b99c802026-08-12WarningsExact identifier
application number: M022
Gingicaine Gel Variety PakGINGICAINE GEL VARIETY PAKGingi-Pak a Division of the Belport62ed4ff3-18f6-5c67-e053-2991aa0a77922026-08-11WarningsExact identifier
application number: M022
Hydrogen Peroxide 3 Percent ReadyInCaseHYDROGEN PEROXIDEP & L Development, LLCb0866db5-3b0d-4478-9b3b-1f077d2f53932026-08-06WarningsExact identifier
application number: M022
Ollie Fresh MintSODIUM FLUORIDE, POTASSIUM NITRATEBrio Product Group LLC.ebeec44f-3c22-43f2-9256-6ece6025c1052026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.5868c5a1-273f-f023-e063-6394a90ac9d82026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.58690bb5-9604-26a4-e063-6394a90afdbe2026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.586918cf-7b13-5999-e063-6294a90a88a92026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.586924a0-322d-5dc3-e063-6294a90a15562026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.58692e90-de74-52d3-e063-6394a90a97022026-08-06WarningsExact identifier
application number: M022
Candee Caine Topical AnestheticBENZOCAINETop Quality Manufacturing, Inc.586937ae-46af-7066-e063-6294a90ae53e2026-08-06WarningsExact identifier
application number: M022
Freshness Blueberry Toothpaste100gFRESHNESS BLUEBERRY TOOTHPASTE 100GWORLD DENTISTS ASSOCIATION AMERICA LIMITED586d1dba-87fc-b676-e063-6294a90a14702026-08-06WarningsExact identifier
application number: M022

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1100924cetylpyridinium chloride 0.07 % Oral RinsePSN8867d791-7e93-4f39-aaaf-bfbee8296fd914
1251371Crest Pro-Health 0.07 % Oral RinsePSN8867d791-7e93-4f39-aaaf-bfbee8296fd914
1251371cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash]SBD8867d791-7e93-4f39-aaaf-bfbee8296fd914
1100924cetylpyridinium chloride 0.7 MG/ML MouthwashSCD8867d791-7e93-4f39-aaaf-bfbee8296fd914
1100924cetylpyridinium chloride 0.07 % Oral RinseSY8867d791-7e93-4f39-aaaf-bfbee8296fd914
1251371Crest 0.07 % MouthwashSY8867d791-7e93-4f39-aaaf-bfbee8296fd914
1100924cetylpyridinium chloride 0.07 % Oral RinsePSN65bf17a9-21ad-27cb-e053-2991aa0afc404
1251371Crest Pro-Health 0.07 % Oral RinsePSN65bf17a9-21ad-27cb-e053-2991aa0afc404
1251371cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash]SBD65bf17a9-21ad-27cb-e053-2991aa0afc404
1100924cetylpyridinium chloride 0.7 MG/ML MouthwashSCD65bf17a9-21ad-27cb-e053-2991aa0afc404
1100924cetylpyridinium chloride 0.07 % Oral RinseSY65bf17a9-21ad-27cb-e053-2991aa0afc404
1251371Crest 0.07 % MouthwashSY65bf17a9-21ad-27cb-e053-2991aa0afc404

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
37000-451-013700004510136 mL in 1 BOTTLE, PLASTIC (37000-451-01) 36 ml2011-02-030000-00-00NoNoCurrent
37000-451-0237000045102100 mL in 1 BOTTLE, PLASTIC (37000-451-02) 100 ml2021-01-010000-00-00NoNoCurrent
37000-451-0337000045103250 mL in 1 BOTTLE, PLASTIC (37000-451-03) 250 ml2011-02-030000-00-00NoNoCurrent
37000-451-0437000045104500 mL in 1 BOTTLE, PLASTIC (37000-451-04) 500 ml2011-02-030000-00-00NoNoCurrent
37000-451-05370000451051000 mL in 1 BOTTLE, PLASTIC (37000-451-05) 1000 ml2011-02-030000-00-00NoNoCurrent
37000-451-06370000451061500 mL in 1 BOTTLE, PLASTIC (37000-451-06) 1500 ml2011-02-030000-00-00NoNoCurrent
37000-451-10370000451102 BOTTLE in 1 PACKAGE (37000-451-10) > 1000 mL in 1 BOTTLE2 bottle2011-02-030000-00-00NoNoCurrent
37000-451-11370000451113 BOTTLE, PLASTIC in 1 CELLO PACK (37000-451-11) / 1000 mL in 1 BOTTLE, PLASTIC2011-02-03NoNoCurrent