Crest Pro-Health Multi-Protection
- Product NDC
- 37000-451
- 11-digit product format
- 370000451
- Labeler code
- 37000
- Product ID
- 37000-451_47e4e758-d6de-4e88-e063-6394a90ac40e
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Cetylpyridinium chloride
- Dosage form
- RINSE
- Route
- ORAL
- Labeler
- The Procter & Gamble Manufacturing Company
- Application
- M022
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2011-02-03
- Substance
- CETYLPYRIDINIUM CHLORIDE
- Active strength
- .014 g/20mL
- NDC exclude flag
- No
- Listing certified through
- 2027-12-31
- Current FDA listing
- Yes
NDC auxiliary status#
These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.
| Dataset | Scope | Product NDC | Package NDC | Code | Status | Reporting period | Source date |
|---|---|---|---|---|---|---|---|
| excluded package | package | 37000-451 | 37000-451-10 | D | Discontinued by firm | 2026-10-15 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- Crest Pro-Health Multi-Protection
- Brand name suffix
- Refreshing Clean Mint
- Listing expiration
- 2027-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| CETYLPYRIDINIUM CHLORIDE | .014 g/20mL |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| D9OM4SK49P | Internal UNII lookup |
Harmonized RxCUI identifiers#
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | Available on FDA.report |
FDA-Initiated Inactive NDC Indexing#
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 37000-451-01 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 36 mL in 1 BOTTLE, PLASTIC | RINSE | 36 | 14 | |
| 37000-451-02 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 100 mL in 1 BOTTLE, PLASTIC | RINSE | 100 | 14 | |
| 37000-451-03 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 250 mL in 1 BOTTLE, PLASTIC | RINSE | 250 | 14 | |
| 37000-451-04 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 500 mL in 1 BOTTLE, PLASTIC | RINSE | 500 | 14 | |
| 37000-451-05 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE, PLASTIC | RINSE | 1000 | 14 | |
| 37000-451-06 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1500 mL in 1 BOTTLE, PLASTIC | RINSE | 1500 | 14 | |
| 37000-451-10 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 2 in 1 PACKAGE | RINSE | 2 | 14 | |
| 37000-451-10 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE | RINSE | 1000 | 14 | |
| 37000-451-11 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 3 in 1 CELLO PACK | RINSE | 3 | 14 | |
| 37000-451-11 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE, PLASTIC | RINSE | 1000 | 14 |
DailyMed Socrata Ingredients#
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 37000-451 | CREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [THE PROCTER & GAMBLE MANUFACTURING COMPANY] | 11 | Current NDC, Legacy NDC, 10 package rows | 20250309_8867d791-7e93-4f39-aaaf-bfbee8296fd9.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Sensitive Whitening Tooth-paste | POTASSIUM NITRATE, SODIUM FLUORIDE | Meijer, Inc. | c25b6a95-e604-48e3-bc55-595969d1ce9b | 2025-12-23 | Warnings | M022 |
| parodontax Active Gum Repair | STANNOUS FLUORIDE | Haleon US Holdings LLC | b51ccdd9-c0af-4caa-ad97-ad1d1423b76b | 2025-12-22 | Warnings | M022 |
| parodontax Complete Protection | STANNOUS FLUORIDE | Haleon US Holdings LLC | 59bb84d6-6fd3-4586-bccf-7dc45cbbb39c | 2025-12-22 | Warnings | M022 |
| parodontax Complete Protection | STANNOUS FLUORIDE | Haleon US Holdings LLC | f6912712-ce9b-44aa-8953-b9a8d420f458 | 2025-12-22 | Warnings | M022 |
| parodontax Active Gum Repair Whitening | STANNOUS FLUORIDE | Haleon US Holdings LLC | 817e804c-e55e-4d77-9ab9-ff54ae794725 | 2025-12-22 | Warnings | M022 |
| parodontax Active Gum Repair Breath Freshener | STANNOUS FLUORIDE | Haleon US Holdings LLC | addcb1e2-24b9-4367-adf3-6806e2439a80 | 2025-12-22 | Warnings | M022 |
| parodontax | STANNOUS FLUORIDE | Haleon US Holdings LLC | 0f07aa1a-97be-44af-92d8-a10777e24e0a | 2025-12-22 | Warnings | M022 |
| R B one | PHOSPHATIDYLSERINE, ZINC OXIDE | NPG Bio Pharmaceuticals Co.,Ltd. | 410c40fd-cf94-0301-e063-6294a90ae2de | 2025-12-18 | Warnings | M022 |
| Dem Zero | PHOSPHATIDYLSERINE, MAGNESIUM OXIDE | NPG Bio Pharmaceuticals Co.,Ltd. | 411f1a0f-ed02-cc78-e063-6394a90a0aec | 2025-12-18 | Warnings | M022 |
| Res B one | PHOSPHATIDYLSERINE, ZINC OXIDE | NPG Bio Pharmaceuticals Co.,Ltd. | 21469f58-1d70-774f-e063-6294a90af039 | 2025-12-18 | Warnings | M022 |
| Alzh L | PHOSPHATIDYLSERINE, MAGNESIUM OXIDE | NPG Bio Pharmaceuticals Co.,Ltd. | 41056de0-aaa2-01bb-e063-6394a90af7b8 | 2025-12-18 | Warnings | M022 |
| Lemon | GLYCERIN | TwinMed LLC | fc88eec0-c66c-5d6d-e053-6294a90a13d2 | 2025-12-18 | Warnings | M022 |
| CloSYS | HYDROGEN PEROXIDE | Rowpar Pharmaceuticals, Inc. | 299fc7b1-af6d-4bf9-810f-d35283423fe2 | 2025-12-17 | Warnings | M022 |
| Ipana 20% Benzocaine Topical | BENZOCAINE | Maxill Inc. | c13761e0-d45d-4e0f-ac41-428e005f96bb | 2025-12-17 | Warnings | M022 |
| Ipana 20% Benzocaine Topical | BENZOCAINE | Maxill Inc. | 6dca566b-cb6a-43c4-b6e2-f2bad77fb932 | 2025-12-17 | Warnings | M022 |
| Ipana 20% Benzocaine Topical | BENZOCAINE | Maxill Inc. | f36bb9bd-e9bc-4f35-a388-e0ffadbce6ab | 2025-12-17 | Warnings | M022 |
| Ipana 20% Benzocaine Topical | BENZOCAINE | Maxill Inc. | 7ede08e5-2dfe-4183-905d-28d1cea42407 | 2025-12-17 | Warnings | M022 |
| Ipana 20% Benzocaine Topical | BENZOCAINE | Maxill Inc. | 9de36e4f-f966-4a58-b4bf-9ac3b86b3f09 | 2025-12-17 | Warnings | M022 |
| Hydrogen Peroxide | HYDROGEN PEROXIDE | CVS PHARMACY, INC | 3b0ad9ac-4920-45a7-b336-dfa7f8d9bdb2 | 2025-12-17 | Warnings | M022 |
| Sore Throat | PHENOL | EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC) | 9128d59c-6fa9-4358-865a-802257a9bd25 | 2025-12-16 | Warnings | M022 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | PSN | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | Crest Pro-Health 0.07 % Oral Rinse | PSN | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash] | SBD | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.7 MG/ML Mouthwash | SCD | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | SY | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | Crest 0.07 % Mouthwash | SY | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | PSN | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | Crest Pro-Health 0.07 % Oral Rinse | PSN | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash] | SBD | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1100924 | cetylpyridinium chloride 0.7 MG/ML Mouthwash | SCD | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | SY | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | Crest 0.07 % Mouthwash | SY | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Marketing end | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|---|
| 37000-451-01 | 37000045101 | 36 mL in 1 BOTTLE, PLASTIC (37000-451-01) | 36 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-02 | 37000045102 | 100 mL in 1 BOTTLE, PLASTIC (37000-451-02) | 100 ml | 2021-01-01 | 0000-00-00 | No | No | Current |
| 37000-451-03 | 37000045103 | 250 mL in 1 BOTTLE, PLASTIC (37000-451-03) | 250 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-04 | 37000045104 | 500 mL in 1 BOTTLE, PLASTIC (37000-451-04) | 500 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-05 | 37000045105 | 1000 mL in 1 BOTTLE, PLASTIC (37000-451-05) | 1000 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-06 | 37000045106 | 1500 mL in 1 BOTTLE, PLASTIC (37000-451-06) | 1500 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-10 | 37000045110 | 2 BOTTLE in 1 PACKAGE (37000-451-10) > 1000 mL in 1 BOTTLE | 2 bottle | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-11 | 37000045111 | 3 BOTTLE, PLASTIC in 1 CELLO PACK (37000-451-11) / 1000 mL in 1 BOTTLE, PLASTIC | 2011-02-03 | No | No | Current |