Crest Premium Plus

Product NDC: 37000-993
11-digit product format: 370000993
Labeler code: 37000
Product ID: 37000-993_47e343c9-2e62-c288-e063-6394a90a0b5c
Type: HUMAN OTC DRUG
Nonproprietary name: Sodium Fluoride
Dosage form: PASTE, DENTIFRICE
Route: DENTAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M021
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2021-01-01
Substance: SODIUM FLUORIDE
Active strength: 1.5 mg/g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	37000-993	37000-993-35	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	37000-993-35	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	37000-993-35	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	37000-993-52	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	37000-993-52	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	37000-993-52	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	37000-993-52	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	37000-993-52	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	37000-993-52	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	37000-993-52	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	37000-993-52	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	37000-993-52	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	37000-993-52	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Crest Premium Plus
Brand name suffix: Advanced Whitening Active Foam
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
SODIUM FLUORIDE	1.5 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8ZYQ1474W7	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
891775	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
b81a22dc-b759-24cd-e053-2995a90a9148	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
37000-993-52	2023-03-31	Crest Premium Plus Advanced Whitening Active Foam
37000-993-52	2023-03-31	Crest Premium Plus Advanced Whitening Active Foam
37000-993-72	2023-03-31	Crest Premium Plus Advanced Whitening Active Foam
37000-993-72	2023-03-31	Crest Premium Plus Advanced Whitening Active Foam
37000-993-52	2023-01-30	Crest Premium Plus Advanced Whitening Active Foam
37000-993-52	2023-01-30	Crest Premium Plus Advanced Whitening Active Foam
37000-993-72	2023-01-30	Crest Premium Plus Advanced Whitening Active Foam
37000-993-72	2023-01-30	Crest Premium Plus Advanced Whitening Active Foam

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
37000-993-35	Crest Premium PlusAdvanced Whitening Active Foam	3 in 1 CARTON	PASTE, DENTIFRICE	3	12
37000-993-35	Crest Premium PlusAdvanced Whitening Active Foam	147 g in 1 TUBE	PASTE, DENTIFRICE	147	12
37000-993-52	Crest Premium PlusAdvanced Whitening Active Foam	147 g in 1 TUBE	PASTE, DENTIFRICE	147	12
37000-993-52	Crest Premium PlusAdvanced Whitening Active Foam	1 in 1 CARTON	PASTE, DENTIFRICE	1	12
37000-993-72	Crest Premium PlusAdvanced Whitening Active Foam	1 in 1 CARTON	PASTE, DENTIFRICE	1	12
37000-993-72	Crest Premium PlusAdvanced Whitening Active Foam	204 g in 1 TUBE	PASTE, DENTIFRICE	204	12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
37000-993	CREST PREMIUM PLUS ADVANCED WHITENING ACTIVE FOAM (SODIUM FLUORIDE) PASTE, DENTIFRICE [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	10	Current NDC, Legacy NDC, 6 package rows	20250115_b81a22dc-b759-24cd-e053-2995a90a9148.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 18 of 50 · 995 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Anticavity Fluoride Rinse	SODIUM FLUORIDE	Lidl US, LLC	c47475aa-3125-410f-aa31-0add6e4ce125	2026-02-04	Warnings, Adverse reactions	Exact identifier application number: M021
Crest 3D White Brilliance Pro Ultra White	SODIUM MONOFLUOROPHOSPHATE	The Procter & Gamble Manufacturing Company	f4c02924-95ee-09d2-e053-2995a90a8121	2026-02-03		Exact identifier application number: M021
Crest 3D White Stain Eraser Icy Clean Mint	SODIUM FLUORIDE	The Procter & Gamble Manufacturing Company	f5d97011-7be3-3b1c-e053-2a95a90ade86	2026-02-03		Exact identifier application number: M021
Anticavity	SODIUM FLUORIDE	Demoulas Super Markets, Inc.	c28c3475-efbb-4099-83ab-ab91bac9dfc3	2026-02-03	Warnings, Adverse reactions	Exact identifier application number: M021
Anticavity Fluoride Rinse	SODIUM FLUORIDE	Demoulas Super Markets, Inc	65abfb4d-3a1e-42df-b343-f270ce60a3bf	2026-02-03	Warnings, Adverse reactions	Exact identifier application number: M021
Crest Cavity Protection Cool Mint Gel	SODIUM FLUORIDE	The Procter & Gamble Manufacturing Company	102e4d9c-0fae-d48a-e063-6294a90aac94	2026-02-03	Warnings	Exact identifier application number: M021
Crest Plus Tartar Protection	SODIUM FLUORIDE	The Procter & Gamble Manufacturing Company	08767b0f-ed6e-8d32-e063-6294a90a10cd	2026-02-03	Warnings	Exact identifier application number: M021
Crest Braces Care Anticavity Fluoride Rinse	SODIUM FLUORIDE	The Procter & Gamble Manufacturing Company	d8398cfd-9af6-690d-e053-2995a90a9b7c	2026-02-03	Warnings	Exact identifier application number: M021
AutoBrush bubblegum	SODIUM FLUORIDE	Lander Enterprises, LLC	2e85d6f7-2df8-4eb9-bc97-d7b7af7fb460	2026-02-03	Warnings	Exact identifier application number: M021
AutoBrush Mint	SODIUM FLUORIDE	Lander Enterprises, LLC	d859d02d-a036-4d90-bed4-9a5c31e9e1ef	2026-02-03	Warnings	Exact identifier application number: M021
Glowing White	SODIUM FLUORIDE	Demoulas Super Markets, Inc	32faf47d-b64f-4454-9f14-51503504c6b5	2026-02-03	Warnings, Adverse reactions	Exact identifier application number: M021
Sodium fluoride	SODIUM FLUORIDE	Demoulas Super Markets, Inc	2f5d3c75-1a11-47e1-b297-e2302177efe7	2026-02-03	Warnings, Adverse reactions	Exact identifier application number: M021
Anticavity	SODIUM FLUORIDE	Demoulas Super Markets, Inc	096e6a1d-316b-432a-bf27-70e8a13337cc	2026-02-03	Warnings, Adverse reactions	Exact identifier application number: M021
Listerine Total Care Extra Mild Alcohol Free Anticavity Fluoride Mouthwash	SODIUM FLUORIDE	Kenvue Brands LLC	49d1932f-a85c-7b8f-e063-6394a90a6aca	2026-02-02	Warnings	Exact identifier application number: M021
Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash	SODIUM FLUORIDE	Kenvue Brands LLC	49d4f96f-e61f-e6e6-e063-6294a90ab0a0	2026-02-02	Warnings	Exact identifier application number: M021
Brush Buddies Mouthwash Toy Story Wild West Watermelon	SODIUM FLUORIDE	Kingkey MBC Life Technology Group co., LTD.	49d69901-0b07-b07d-e063-6394a90a3c34	2026-02-02	Warnings	Exact identifier application number: M021
Brush Buddies Mouthwash Frozen Blizzard Berry	SODIUM FLUORIDE	Kingkey MBC Life Technology Group co., LTD.	49d6c1c9-cd21-cac6-e063-6294a90a81d6	2026-02-02	Warnings	Exact identifier application number: M021
Brush Buddies Mouthwash Disney Princesses Grand Grape	SODIUM FLUORIDE	Kingkey MBC Life Technology Group co., LTD.	49d6f926-da4e-26df-e063-6294a90a1c0c	2026-02-02	Warnings	Exact identifier application number: M021
Brush Buddies Mouthwash Spidey and Hist Amazing Friends Peter Parker Punch	SODIUM FLUORIDE	Kingkey MBC Life Technology Group co., LTD.	49d70b88-d57c-37cd-e063-6294a90a4a59	2026-02-02	Warnings	Exact identifier application number: M021
Anticavity	SODIUM FLUORIDE	Rite Aid Corporation	54a8b884-969a-4a41-ac2a-bc1f1fe9f7fe	2026-02-02	Warnings, Adverse reactions	Exact identifier application number: M021

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
8ZYQ1474W7	SODIUM FLUORIDE	7681-49-4	SODIUM FLUORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
891775	sodium fluoride 0.243 % Toothpaste	PSN	b81a22dc-b759-24cd-e053-2995a90a9148	12
891775	sodium fluoride 0.00243 MG/MG Toothpaste	SCD	b81a22dc-b759-24cd-e053-2995a90a9148	12
891775	sodium fluoride 0.243 % (fluoride ion 0.13 % ) Toothpaste	SY	b81a22dc-b759-24cd-e053-2995a90a9148	12
891775	sodium fluoride 0.243 % (fluoride ion 0.14 % ) Toothpaste	SY	b81a22dc-b759-24cd-e053-2995a90a9148	12
891775	sodium fluoride 0.243 % (fluoride ion 0.15 % ) Toothpaste	SY	b81a22dc-b759-24cd-e053-2995a90a9148	12
891775	sodium fluoride 0.243 % (fluoride ion 0.16 % ) Toothpaste	SY	b81a22dc-b759-24cd-e053-2995a90a9148	12

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
37000-993-35	37000099335	3 in 1 CARTON						Historical
37000-993-52	37000099352	1 TUBE in 1 CARTON (37000-993-52) / 147 g in 1 TUBE	1 tube	2021-01-01	0000-00-00	No	No	Current
37000-993-72	37000099372	1 TUBE in 1 CARTON (37000-993-72) / 204 g in 1 TUBE	1 tube	2021-01-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Crest Premium Plus Advanced Whitening Active Foam	The Procter & Gamble Manufacturing Company	2026-01-08	HUMAN OTC DRUG LABEL	12