PROMETHAZINE HYDROCHLORIDE

Product NDC
39822-5550
11-digit product format
398225550
Labeler code
39822
Product ID
39822-5550_0e860109-725f-1c28-e063-6394a90a50ef
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PROMETHAZINE HYDROCHLORIDE
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
XGen Pharmaceuticals DJB, Inc.
Application
ANDA040737
Marketing category
ANDA
Marketing start
2015-01-30
Substance
PROMETHAZINE HYDROCHLORIDE
Active strength
50 mg/mL
Pharmacologic classes
Phenothiazine [EPC], Phenothiazines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040737-001PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24
A040737-002PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A040737-001AP
A040737-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24d06236e962d9…
2024-10-29 15:01 UTC2024-10A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-241e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-248072bd15b7f6…
2024-05-31 18:47 UTC2024-05A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-245c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-245d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-244b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-2474a2ff9319b5…
2019-12-13 00:20 UTC2019-12A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040737-001PROMETHAZINE HYDROCHLORIDE25MG/MLINJECTABLE / INJECTIONAP2008-04-24782e0a99824c…
2021-12-28 21:50 UTC2021-12A040737-002PROMETHAZINE HYDROCHLORIDE50MG/MLINJECTABLE / INJECTIONAP2008-04-24782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A040737-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040737-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040737-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040737-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040737-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040737-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040737-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040737-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040737-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040737-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040737-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040737-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040737-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040737-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040737-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040737-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040737-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040737-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040737-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A040737-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040737-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040737-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040737-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040737-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040737-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040737-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040737-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A040737-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040737-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040737-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040737-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A040737-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040737-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A040737-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040737-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A040737-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040737-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A040737-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040737-001AP1782e0a99824c…
2021-12-28 21:50 UTC2021-12A040737-002AP1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
PROMETHAZINE HYDROCHLORIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROMETHAZINE HYDROCHLORIDE50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
R61ZEH7I1IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
992858Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
b6f6698f-f23c-452a-9b38-bbb96ab88ae4Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2Product name520250304
3036445d-7d13-4411-a100-f2ac5ab8a276Product name120240110
6bd95106-a412-1dad-b9cc-4cb74bfb27ceProduct name220230315
2e7222fb-e3f1-febd-962f-ddbb495d6b5fProduct name220220126
09d8330d-4fec-be98-3a66-f985140646b2Product name220210513
444b3e50-f226-46ef-bfca-2e7035d140cdProduct name120190611
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
4f881de7-085a-407e-abc2-faa3c0127432Product name120170811
e0b6c8be-f2bd-9f86-a9fc-3ed56ffaa814Product name320150910
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
290f523a-f9db-9774-b5a9-e1f908ac1782Product name120150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
76633df9-0d59-4b88-03ed-21dee1b966f8Product name120140508
87711080-88eb-65c5-b2dd-bf99e700a372Product name120140508
c6b65c52-69c7-df49-550a-a50c137f6218Product name120140508
d51697af-7f97-0559-95d1-fe94f3f031d5Product name120140508
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508
e949165d-714d-e548-2b76-0cb5def16f30Product name120140508
ec2149b3-5c6d-5344-f757-c86411073075Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
39822-5550-5PROMETHAZINE HYDROCHLORIDE1 mL in 1 AMPULEINJECTION, SOLUTION16
39822-5550-6PROMETHAZINE HYDROCHLORIDE25 in 1 CARTONINJECTION, SOLUTION256

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
39822-5550PROMETHAZINE HYDROCHLORIDE INJECTION, SOLUTION [XGEN PHARMACEUTICALS DJB, INC.]6Current NDC, Legacy NDC, 2 package rows20240113_b6f6698f-f23c-452a-9b38-bbb96ab88ae4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDEProPharma Distribution45b09a50-dab2-e83d-e063-6394a90aa8132025-12-11Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040737
application number: ANDA040737
PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDEXGen Pharmaceuticals DJB, Inc.b6f6698f-f23c-452a-9b38-bbb96ab88ae42024-01-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040737
application number: ANDA040737
ndc (product): 39822-5550
PROMETHAZINE HYDROCHLORIDEPROMETHAZINE HYDROCHLORIDEXGen Pharmaceuticals DJB, Inc.1d02d52b-84bb-4e81-b352-125029eb39f62024-01-05Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040737
application number: ANDA040737

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
992858promethazine HCl 50 MG in 1 ML InjectionPSNb6f6698f-f23c-452a-9b38-bbb96ab88ae46
9928581 ML promethazine hydrochloride 50 MG/ML InjectionSCDb6f6698f-f23c-452a-9b38-bbb96ab88ae46
992858promethazine HCl 50 MG per 1 ML InjectionSYb6f6698f-f23c-452a-9b38-bbb96ab88ae46

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
39822-5550-5398225550051 mL in 1 AMPULE1 mlHistorical
39822-5550-63982255500625 AMPULE in 1 CARTON (39822-5550-6) / 1 mL in 1 AMPULE (39822-5550-5) 25 ampule2015-01-300000-00-00NoNoCurrent