Home NDC 41167-0040 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever
Product NDC 41167-0040
11-digit product format 411670040
Labeler code 41167
Product ID 41167-0040_75e0be81-2c6a-461a-9da5-c2aa060e2dc8
Type HUMAN OTC DRUG
Nonproprietary name Acetaminophen and Diphenhydramine Hydrochloride
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Chattem, Inc.
Application M013
Marketing category OTC MONOGRAPH DRUG
Marketing start 2009-12-01
Substance ACETAMINOPHEN; DIPHENHYDRAMINE HYDROCHLORIDE
Active strength 325; 50 mg/1; mg/1
Pharmacologic classes Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 12 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Snapshot, Source SHA-256 table Captured / source date Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 0efc9e666f02…f202fb6c5f17…2024-11-09 02:27 UTC · source 2024-11-08 ad56d346431e…cc804d4bbf1e…2024-10-04 04:10 UTC · source 2024-10-03 367a005e9d99…383a685ebd0f…2024-07-10 04:00 UTC · source 2024-07-09 557ba5c1ecfa…9c80585c8c6e…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Unisom PM Pain Nighttime Sleep Aid and Pain Reliever
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength ACETAMINOPHEN 325 mg/1 DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 362O9ITL9D Internal UNII lookup TC2D6JAD40 Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1093075 Internal RxNorm lookup 1093077 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 41167-0040-2 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 1 in 1 CARTON TABLET, FILM COATED 1 9 41167-0040-2 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 15 in 1 BOTTLE TABLET, FILM COATED 15 9 41167-0040-3 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 1 in 1 CARTON TABLET, FILM COATED 1 9 41167-0040-3 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 20 in 1 BOTTLE TABLET, FILM COATED 20 9 41167-0040-4 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 30 in 1 BOTTLE TABLET, FILM COATED 30 9 41167-0040-4 Unisom PM Pain Nighttime Sleep Aid and Pain Reliever 1 in 1 CARTON TABLET, FILM COATED 1 9
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded ACETAMINOPHEN ACTIVE INGREDIENT 362O9ITL9D UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 DIPHENHYDRAMINE HYDROCHLORIDE ACTIVE INGREDIENT TC2D6JAD40 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 ACETAMINOPHEN ACTIVE MOIETY 362O9ITL9D UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 DIPHENHYDRAMINE ACTIVE MOIETY 8GTS82S83M UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 ANHYDROUS DIBASIC CALCIUM PHOSPHATE INACTIVE INGREDIENT L11K75P92J UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 CROSCARMELLOSE SODIUM INACTIVE INGREDIENT M28OL1HH48 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 FD&C BLUE NO. 1 INACTIVE INGREDIENT H3R47K3TBD UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 HYDROXYPROPYL CELLULOSE INACTIVE INGREDIENT RFW2ET671P UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 HYPROMELLOSE INACTIVE INGREDIENT 3NXW29V3WO UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 MAGNESIUM SILICATE INACTIVE INGREDIENT 9B9691B2N9 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 MAGNESIUM STEARATE INACTIVE INGREDIENT 70097M6I30 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 MINERAL OIL INACTIVE INGREDIENT T5L8T28FGP UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 SILICON DIOXIDE INACTIVE INGREDIENT ETJ7Z6XBU4 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 STARCH, PREGELATINIZED CORN INACTIVE INGREDIENT O8232NY3SJ UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1 STEARIC ACID INACTIVE INGREDIENT 4ELV7Z65AP UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET [CHATTEM, INC.] 1
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 41167-0040 UNISOM PM PAIN NIGHTTIME SLEEP AID AND PAIN RELIEVER (ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE) TABLET, FILM COATED [CHATTEM, INC.] 8 Current NDC, Legacy NDC, 6 package rows 20231007_451daeeb-88a9-44b1-9a2d-1ff0b0ec41cb.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 2 of 79 · 1,579 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join MAX relief junior ACETAMINOPHEN Akron Pharma Inc. 0e43b885-3843-4f11-9a53-02a38c228313 2026-08-31 Warnings Exact identifier application number: M013 MAX relief junior CHILDREN ACETAMINOPHEN Akron Pharma Inc. d7874e4d-0b38-4bb1-9a62-aa4f66d9baf9 2026-08-31 Warnings Exact identifier application number: M013 MAX relief junior Grape CHILDREN ACETAMINOPHEN Akron Pharma Inc. 3c7a7f40-4963-4fd1-942e-93fa08a45830 2026-08-31 Warnings Exact identifier application number: M013 Genexa Kids Pain and Fever ACETAMINOPHEN Genexa Inc. 5a615118-33c9-1520-e063-6394a90a21a6 2026-08-31 Warnings Exact identifier application number: M013 acetaminophen extra strength ACETAMINOPHEN Sam's West Inc dd99efd0-4ca4-4dc6-a940-bebd17ac8f8d 2026-08-28 Warnings Exact identifier application number: M013 Aspirin 81 mg ASPIRIN HAWAII REPACK, INC. ac94cce3-9a39-41de-bb8b-10a5e5b8e83b 2026-08-28 Warnings Exact identifier application number: M013 Aspirin ASPIRIN WinCo Foods, LLC a0a19cd1-eb8a-4773-be00-78de90d2a3c3 2026-08-28 Warnings Exact identifier application number: M013 Childrens Pain and Fever ACETAMINOPHEN FSA STORE INC. 5502ef15-9f40-db56-e063-6394a90a2de4 2026-08-26 Warnings Exact identifier application number: M013 Dye Free Pain and Fever Childrens ACETAMINOPHEN Walgreens 3ea217dd-e5b9-4d4b-861a-76ce61ba3a1d 2026-08-26 Warnings Exact identifier application number: M013 HyVee Extra Strength Headache Relief CAPLET ACETAMINOPHEN, ASPIRIN, CAFFEINE HyVee Inc 495c75bf-c09a-accd-e063-6294a90a75ec 2026-08-24 Warnings Exact identifier application number: M013 Acetaminophen ACETAMINOPHEN Walgreens 543f93d1-df14-0bd2-e063-6294a90a4413 2026-08-24 Warnings Exact identifier application number: M013 ACETAMINOPHEN ACETAMINOPHEN Akron Pharma Inc. ab79fd60-8315-4c63-8045-1b0511ac268f 2026-08-24 Warnings Exact identifier application number: M013 Genexa Infants Pain and Fever ACETAMINOPHEN Genexa Inc. 4fd048c3-70bc-2ea7-e063-6394a90a55f2 2026-08-22 Warnings Exact identifier application number: M013 Genexa Kids Pain and Fever ACETAMINOPHEN Genexa Inc. 59adabeb-97e8-2de4-e063-6394a90acc47 2026-08-22 Warnings Exact identifier application number: M013 Headache Relief ACETAMINOPHEN, ASPIRIN, CAFFEINE Publix Super Markets Inc a876daa7-ade3-497d-87bb-46d6e4dc185a 2026-08-21 Warnings Exact identifier application number: M013 equate aspirin ASPIRIN Wal-Mart Stores Inc ea3f8eed-7b70-4156-9586-125d27bf29a8 2026-08-19 Warnings Exact identifier application number: M013 aspirin chewable, low dose ASPIRIN United Natural Foods, Inc. dba UNFI 6a6ac7fe-91a4-4b55-979a-b53b51505d8b 2026-08-19 Warnings Exact identifier application number: M013 Acetaminophen ACETAMINOPHEN Sam's West Inc 1098d0e7-8202-4018-a2d2-b0c80ee58b56 2026-08-19 Warnings Exact identifier application number: M013 Headache Relief Extra Strength ACETAMINOPHEN, ASPIRIN, CAFFEINE Safeway, Inc. 5e77dca4-2ff8-4a8c-94bd-f224b680ca23 2026-08-19 Warnings Exact identifier application number: M013 dg health pain relief pm extra strength ACETAMINOPHEN, DIPHENHYDRAMINE HCL Dolgencorp Inc 4d1eddf0-eff7-4c47-b312-30dee08d9e5f 2026-08-19 Warnings Exact identifier application number: M013
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 41167-0040-2 41167004002 1 BOTTLE in 1 CARTON (41167-0040-2) / 15 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2009-12-01 0000-00-00 No No Current 41167-0040-3 41167004003 1 in 1 CARTON Historical 41167-0040-4 41167004004 1 BOTTLE in 1 CARTON (41167-0040-4) / 30 TABLET, FILM COATED in 1 BOTTLE 1 bottle 2009-12-01 0000-00-00 No No Current