Dandruff

Product NDC: 41250-281
11-digit product format: 412500281
Labeler code: 41250
Product ID: 41250-281_4b3287a3-5f30-dc5e-e063-6394a90a9373
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione zinc 1%
Dosage form: SHAMPOO
Route: TOPICAL
Labeler: Meijer, Inc.
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2002-05-24
Substance: PYRITHIONE ZINC
Active strength: 10 mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	41250-281	41250-281-15	D	Discontinued by firm		2026-10-12
excluded package	package	41250-281	41250-281-35	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	41250-281	41250-281-35	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	41250-281	41250-281-35	D	Discontinued by firm		excluded / ndc_excluded.zip	`f5e01cc5f278…`	`a2eaf40c39c3…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Dandruff
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
28525947-97f6-4b3f-b8bd-596ffcf61188	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
41250-281-15	Dandruff	420 mL in 1 BOTTLE, PLASTIC	SHAMPOO	420	13
41250-281-32	Dandruff	370 mL in 1 BOTTLE, PLASTIC	SHAMPOO	370	13
41250-281-35	Dandruff	700 mL in 1 BOTTLE, PLASTIC	SHAMPOO	700	13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
PYRITHIONE ZINC	ACTIVE INGREDIENT	R953O2RHZ5	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
PYRITHIONE ZINC	ACTIVE MOIETY	R953O2RHZ5	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
ALMOND OIL	INACTIVE INGREDIENT	66YXD4DKO9	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
AMODIMETHICONE (800 CST)	INACTIVE INGREDIENT	363Z2T48P7	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
BENZYL ALCOHOL	INACTIVE INGREDIENT	LKG8494WBH	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
CETRIMONIUM CHLORIDE	INACTIVE INGREDIENT	UC9PE95IBP	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
CETYL ALCOHOL	INACTIVE INGREDIENT	936JST6JCN	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
COCO MONOETHANOLAMIDE	INACTIVE INGREDIENT	C80684146D	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
GLYCOL DISTEARATE	INACTIVE INGREDIENT	13W7MDN21W	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)	INACTIVE INGREDIENT	B16G315W7A	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
MAGNESIUM CARBONATE HYDROXIDE	INACTIVE INGREDIENT	YQO029V1L4	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
MAGNESIUM SULFATE	INACTIVE INGREDIENT	DE08037SAB	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
METHYLCHLOROISOTHIAZOLINONE	INACTIVE INGREDIENT	DEL7T5QRPN	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
METHYLISOTHIAZOLINONE	INACTIVE INGREDIENT	229D0E1QFA	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM BENZOATE	INACTIVE INGREDIENT	OJ245FE5EU	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM LAURETH SULFATE	INACTIVE INGREDIENT	BPV390UAP0	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM LAURYL SULFATE	INACTIVE INGREDIENT	368GB5141J	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
SODIUM XYLENESULFONATE	INACTIVE INGREDIENT	G4LZF950UR	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
TRIDECETH-12	INACTIVE INGREDIENT	YFY3KG5Y7O	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1
ZINC CARBONATE	INACTIVE INGREDIENT	EQR32Y7H0M	DANDRUFF (PYRITHIONE ZINC) SHAMPOO [MEIJER DISTRIBUTION, INC]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
41250-281	DANDRUFF (PYRITHIONE ZINC 1%) SHAMPOO [MEIJER DISTRIBUTION, INC]	11	Current NDC, Legacy NDC, 3 package rows	20250412_28525947-97f6-4b3f-b8bd-596ffcf61188.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 14 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Head and Shoulders Itchy Scalp 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	157c3f81-f37e-4dab-b724-50fe0d9e1a26	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Conditioner Smooth and Silky	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	41709710-539c-3119-e054-00144ff88e88	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Dry Scalp Care Hair and Scalp Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	42620236-17ef-5c70-e054-00144ff88e88	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Hair and Scalp Conditioner Green Apple	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	4534c7a7-bc4b-3851-e054-00144ff88e88	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders MEN Old Spice Pure Sport	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	7bbfc667-bf9b-08c2-e053-2a91aa0a8009	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Royal Oils Daily Moisture Scalp	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	7b1f81e1-1fee-5be2-e053-2a91aa0aa063	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Royal Oils Instant Soothe Scalp	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	7b20f226-3b0a-2ae5-e053-2a91aa0a2f5a	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Coconut Daily Hair and Scalp Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	7cc10c1b-fe0b-7d4c-e053-2a91aa0a2377	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Men Advanced Series Swagger Old Spice	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	7d3cdf44-ae1d-fed5-e053-2a91aa0a3021	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Supreme Detox and Hydrate	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	8659218e-cb8d-bb44-e053-2a91aa0ae37b	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Supreme Soothe and Strengthen	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	86972263-dcef-358f-e053-2991aa0a734f	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Supreme Color Protect	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	8697a03b-7050-3a49-e053-2a91aa0a7271	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Supreme Detox and Hydrate Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	86ab72bc-4e9d-0075-e053-2a91aa0a1135	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Supreme Soothe and Strengthen Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	86abfdc2-d55b-4adb-e053-2991aa0a54b1	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders MEN Advanced Series Bourbon 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	98480eaa-6798-4efe-e053-2a95a90a869f	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders MEN Advanced Series Sandalwood 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	9858f681-1aca-e481-e053-2a95a90a869d	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Apple Cider Vinegar 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	b698b310-a794-e7f3-e053-2a95a90a47c4	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Clinical Dandruff Defense Dry Scalp Rescue	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	c7bc3942-6943-2ea5-e053-2a95a90a42a9	2025-12-18	Warnings	Exact identifier application number: M032
Royal Oils by head and shoulders Moisture Renewal Scalp Balancing Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	c95e82e4-74fb-9dbf-e053-2a95a90a93e5	2025-12-18	Warnings	Exact identifier application number: M032
Head and Shoulders Moisturizing Avocado Oil	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	d08969cb-24ca-c49c-e053-2a95a90a71d1	2025-12-18	Warnings	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	28525947-97f6-4b3f-b8bd-596ffcf61188	13
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	28525947-97f6-4b3f-b8bd-596ffcf61188	13
209884	zinc pyrithione 1 % Medicated Conditioner	SY	28525947-97f6-4b3f-b8bd-596ffcf61188	13
209884	zinc pyrithione 1 % Medicated Shampoo	SY	28525947-97f6-4b3f-b8bd-596ffcf61188	13

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
41250-281-15	41250028115	420 mL in 1 BOTTLE, PLASTIC	420 ml				Historical
41250-281-32	41250028132	370 mL in 1 BOTTLE, PLASTIC (41250-281-32)	370 ml	2023-12-05	No	No	Current
41250-281-35	41250028135	700 mL in 1 BOTTLE, PLASTIC	700 ml				Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Meijer 281.007/284AK-AN Dandruff Shampoo, Dry Scalp	Meijer, Inc. \| Nice-Pak Products, LLC	2026-02-19	HUMAN OTC DRUG LABEL	13