Home NDC 41250-334-08 Headache Relief
Product NDC 41250-334
Requested package NDC 41250-334-08
11-digit product format 412500334
Labeler code 41250
Product ID 41250-334_746072ad-79e2-4d14-939d-d3c4396b47f2
Type HUMAN OTC DRUG
Nonproprietary name Acetaminophen, Aspirin, Caffeine
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Meijer Distribution Inc
Application M013
Marketing category OTC MONOGRAPH DRUG
Marketing start 2008-03-13
Substance ACETAMINOPHEN; ASPIRIN; CAFFEINE
Active strength 250; 250; 65 mg/1; mg/1; mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Methylxanthine [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Xanthines [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 12 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Snapshot, Source SHA-256 table Captured / source date Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 0efc9e666f02…f202fb6c5f17…2024-11-09 02:27 UTC · source 2024-11-08 ad56d346431e…cc804d4bbf1e…2024-10-04 04:10 UTC · source 2024-10-03 367a005e9d99…383a685ebd0f…2024-07-10 04:00 UTC · source 2024-07-09 557ba5c1ecfa…9c80585c8c6e…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Headache Relief
Brand name suffix Extra Strength
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength ACETAMINOPHEN 250 mg/1 ASPIRIN 250 mg/1 CAFFEINE 65 mg/1
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 41250-334-08 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-08 Headache ReliefExtra Strength 24 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 24 18 41250-334-12 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 18 41250-334-12 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-15 Headache ReliefExtra Strength 50 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 50 18 41250-334-15 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-98 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 18 41250-334-98 Headache ReliefExtra Strength 2 in 1 CARTON TABLET, FILM COATED 2 18
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded ACETAMINOPHEN ACTIVE INGREDIENT 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ASPIRIN ACTIVE INGREDIENT R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CAFFEINE ACTIVE INGREDIENT 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ACETAMINOPHEN ACTIVE MOIETY 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ASPIRIN ACTIVE MOIETY R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CAFFEINE ACTIVE MOIETY 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CROSPOVIDONE INACTIVE INGREDIENT 68401960MK HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 HYPROMELLOSES INACTIVE INGREDIENT 3NXW29V3WO HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 POVIDONES INACTIVE INGREDIENT FZ989GH94E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 SODIUM LAURYL SULFATE INACTIVE INGREDIENT 368GB5141J HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 STEARIC ACID INACTIVE INGREDIENT 4ELV7Z65AP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 41250-334 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN, CAFFEINE) TABLET, FILM COATED [MEIJER DISTRIBUTION INC] 17 Current NDC, Legacy NDC, 8 package rows 20241211_04f2c3ed-4bcf-4b6a-b8fb-0aa6ecb3dca2.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 44 of 79 · 1,570 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Aspirina Cafeina ASPIRIN,CAFFEINE Bayer HealthCare LLC. 2e709acc-325a-baca-e063-6394a90a24be 2025-06-12 Warnings Exact identifier application number: M013 Aspirin ASPIRIN CHAIN DRUG MARKETING ASSOCIATION, INC. 696f55b1-536c-40c4-91f7-b572c39220db 2025-06-11 Warnings Exact identifier application number: M013 Acetaminophen ACETAMINOPHEN CVS Pharmacy, Inc. 6dea9e11-ff99-63c7-e053-2a91aa0a5b54 2025-06-10 Warnings Exact identifier application number: M013 Children Acetaminophen Oral Solution ACETAMINOPHEN MAJOR PHARMACEUTICALS cfca5147-f390-40bd-8f13-c5b3b8d1c5b0 2025-06-09 Warnings Exact identifier application number: M013 Aspirin ASPIRIN Trifecta Pharmaceuticals USA LLC 372be427-acbd-c10c-e063-6294a90a572d 2025-06-09 Warnings Exact identifier application number: M013 Childrens Pain and Fever ACETAMINOPHEN CVS Pharmacy d6c8118c-bf78-4194-9b14-8de33c3ecdb7 2025-06-06 Warnings Exact identifier application number: M013 Dolo-NeuroBion ACETAMINOPHEN BENARD INDUSTRIES INC b8310770-84d1-4a6f-8e23-9974947f92f1 2025-06-04 Warnings Exact identifier application number: M013 Menstrual Complete Maximum Strength ACETAMINOPHEN, CAFFEINE AND PYRILAMINE MALEATE Rite Aid Corporation 69bda7d7-8660-4e8d-b8ac-892a3b1f2124 2025-06-03 Warnings Exact identifier application number: M013 Kids Pain and Fever ACETAMINOPHEN KinderFarms, LLC fb74e8f9-d72f-4681-90bd-df48364405b5 2025-06-01 Warnings Exact identifier application number: M013 Pain and Fever Childrens ACETAMINOPHEN P & L Development, LLC b815fcae-8bba-4737-ac10-29a32fb69275 2025-05-30 Warnings Exact identifier application number: M013 Infants Pain and Fever ACETAMINOPHEN KinderFarms, LLC 81cc4900-226b-4c49-ba9c-5747d2a501b1 2025-05-29 Warnings Exact identifier application number: M013 good sense pain relief pm extra strength ACETAMINOPHEN, DIPHENHYDRAMINE HCL Bryant Ranch Prepack e08a7ab1-4b68-422a-97bd-2c5326633943 2025-05-29 Warnings Exact identifier application number: M013 Acetaminophen Gelcaps ACETAMINOPHEN Kroger 30d3f2d0-da35-7f6f-e063-6294a90a9c22 2025-05-23 Warnings Exact identifier application number: M013 Kids Pain and Fever ACETAMINOPHEN Genexa Inc. fcffa7e6-145c-6bc0-e053-6294a90a4751 2025-05-23 Warnings Exact identifier application number: M013 Pain Relief ACETAMINOPHEN CHAIN DRUG MARKETING ASSOCIATION, INC. 1c083e29-8732-4ecd-ab4b-9038acbd0b9d 2025-05-22 Warnings Exact identifier application number: M013 TYLENOL For Children Plus Adults ACETAMINOPHEN Kenvue Brands LLC 5bb8ef99-a94b-49f9-89f9-cd1ce0a47a42 2025-05-21 Warnings Exact identifier application number: M013 Children Acetaminophen ACETAMINOPHEN AARNA USA INC. 25bcb9d5-f388-4ae7-8037-970ffe8d17f0 2025-05-16 Warnings Exact identifier application number: M013 ACETAMINOPHEN ACETAMINOPHEN HF Acquisition Co LLC, DBA HealthFirst 35478de8-50d0-5d0a-e063-6294a90a88ba 2025-05-16 Warnings Exact identifier application number: M013 Extra Strength Acetaminophen ACETAMINOPHEN Preferred Pharmaceuticals Inc. 95f4b628-6d35-4f6b-91f9-b2d117f8e821 2025-05-16 Warnings Exact identifier application number: M013 good neighbor pharmacy childrens pain and fever ACETAMINOPHEN Amerisource Bergen 268a789b-8f31-4739-9777-523249cac326 2025-05-13 Warnings Exact identifier application number: M013
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 41250-334-08 41250033408 1 BOTTLE, PLASTIC in 1 CARTON (41250-334-08) > 24 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2008-03-13 0000-00-00 No No Current