Amlodipine and Valsartan

Product NDC
42291-022
Requested package NDC
42291-022-30
11-digit product format
422910022
Labeler code
42291
Product ID
42291-022_bf65a563-c414-66e7-e053-2a95a90aa6d4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
amlodipine and valsartan
Dosage form
TABLET
Route
ORAL
Labeler
AvKARE
Application
ANDA090011
Marketing category
ANDA
Marketing start
2018-09-11
Marketing end
0000-00-00
Substance
AMLODIPINE; VALSARTAN
Active strength
10 mg/1; mg/1
Pharmacologic classes
Calcium Channel Antagonists [MoA],Dihydropyridine Calcium Channel Blocker [EPC],Dihydropyridines [CS],Angiotensin 2 Receptor Antagonists [MoA],Angiotensin 2 Receptor Blocker [EPC]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage42291-02242291-022-30DDiscontinued by firm2026-09-14

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090011-001AMLODIPINE BESYLATE AND VALSARTANAMLODIPINE BESYLATE; VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-28
A090011-002AMLODIPINE BESYLATE AND VALSARTANAMLODIPINE BESYLATE; VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-28
A090011-003AMLODIPINE BESYLATE AND VALSARTANAMLODIPINE BESYLATE; VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-28
A090011-004AMLODIPINE BESYLATE AND VALSARTANAMLODIPINE BESYLATE; VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
A090011-001AB
A090011-002AB
A090011-003AB
A090011-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 172 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-2884e616aacf4f…
2026-09-14 22:38:342026-08A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-2884e616aacf4f…
2026-09-14 22:38:342026-08A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-2884e616aacf4f…
2026-09-14 22:38:342026-08A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-2884e616aacf4f…
2026-08-18 06:07:402026-07A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-28caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-28caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-28caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-001AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;160MGTABLET / ORALAB2013-03-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-002AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;160MGTABLET / ORALAB2013-03-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-003AMLODIPINE BESYLATE AND VALSARTANEQ 5MG BASE;320MGTABLET / ORALAB2013-03-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-004AMLODIPINE BESYLATE AND VALSARTANEQ 10MG BASE;320MGTABLET / ORALAB2013-03-285bbf6a4d5a75…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 136 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-09-14 22:38:342026-08A090011-001AB184e616aacf4f…
2026-09-14 22:38:342026-08A090011-002AB184e616aacf4f…
2026-09-14 22:38:342026-08A090011-003AB184e616aacf4f…
2026-09-14 22:38:342026-08A090011-004AB184e616aacf4f…
2026-08-18 06:07:402026-07A090011-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-003AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A090011-004AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A090011-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A090011-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090011-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090011-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A090011-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090011-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090011-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090011-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090011-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090011-004AB15bbf6a4d5a75…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42291-022-30EA - Each42291-022bf4796d3-a341-476a-a079-10c89e732fde12018-10-11

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amlodipine and ValsartanAMLODIPINE AND VALSARTANGolden State Medical Supply, Inc.fed14445-1117-861a-e053-6294a90a2aa32026-04-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090011
application number: ANDA090011
Amlodipine and ValsartanAMLODIPINE AND VALSARTANHeritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.55a1d22e-04ad-4475-9b05-0d534e2891602025-11-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090011
application number: ANDA090011

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
42291-022-304229100223030 TABLET in 1 BOTTLE, PLASTIC (42291-022-30) 30 tablet2018-09-110000-00-00NoNoCurrent