Isradipine

Product NDC
42291-062
11-digit product format
422910062
Labeler code
42291
Product ID
42291-062_485b4749-5065-6c1c-e063-6294a90ade38
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Isradipine
Dosage form
CAPSULE
Route
ORAL
Labeler
AvKARE
Application
ANDA077317
Marketing category
ANDA
Marketing start
2023-06-09
Substance
ISRADIPINE
Active strength
2.5 mg/1
Pharmacologic classes
Calcium Channel Antagonists [MoA], Dihydropyridine Calcium Channel Blocker [EPC], Dihydropyridines [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A077317-001ISRADIPINEISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05
A077317-002ISRADIPINEISRADIPINE5MGCAPSULE / ORALABRS2006-01-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A077317-001AB
A077317-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-052680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-055bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05d06236e962d9…
2024-10-29 15:01 UTC2024-10A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-0579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-051e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-058072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-055c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-055d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-054b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-0574a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077317-001ISRADIPINE2.5MGCAPSULE / ORALAB2006-01-05782e0a99824c…
2021-12-28 21:50 UTC2021-12A077317-002ISRADIPINE5MGCAPSULE / ORALABRS2006-01-05782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A077317-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A077317-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077317-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A077317-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A077317-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A077317-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077317-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A077317-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077317-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A077317-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077317-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A077317-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077317-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A077317-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077317-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A077317-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077317-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A077317-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A077317-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A077317-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077317-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A077317-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077317-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A077317-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077317-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A077317-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A077317-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A077317-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077317-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A077317-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A077317-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A077317-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A077317-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A077317-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A077317-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A077317-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A077317-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A077317-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A077317-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A077317-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Isradipine
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ISRADIPINE2.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
YO1UK1S598Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197848Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fdb4c50e-6e6f-a43d-e053-6294a90aa24fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
8ad7ea44-442f-aa22-0f74-8d99d37b3abfProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42291-062-01Isradipine100 in 1 BOTTLECAPSULE1002

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42291-062-01EA - Each42291-06200d8c54c-f81b-4b43-90cb-c3e0d8adcadf12023-07-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42291-062ISRADIPINE CAPSULE [AVKARE]1Current NDC, 1 package rows20230610_fdb4c50e-6e6f-a43d-e053-6294a90aa24f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IsradipineISRADIPINEAvKAREfdb4c50e-6e6f-a43d-e053-6294a90aa24f2026-01-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077317
application number: ANDA077317
ndc (product): 42291-062
IsradipineISRADIPINETeva Pharmaceuticals USA, Inc.bf3425e0-428d-4bdb-ac9a-3b9d483df83a2023-11-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 077317
application number: ANDA077317

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197848isradipine 2.5 MG Oral CapsulePSNfdb4c50e-6e6f-a43d-e053-6294a90aa24f2
197848isradipine 2.5 MG Oral CapsuleSCDfdb4c50e-6e6f-a43d-e053-6294a90aa24f2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
42291-062-0142291006201100 CAPSULE in 1 BOTTLE (42291-062-01) 100 capsule2023-06-09NoNoCurrent