Zycubo

Product NDC
42358-329
11-digit product format
423580329
Labeler code
42358
Product ID
42358-329_bfd40890-37a6-4847-9b2d-6e6966b6af01
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
copper histidinate
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
SUBCUTANEOUS
Labeler
Sentynl Therapeutics, Inc.
Application
NDA211241
Marketing category
NDA
Marketing start
2026-01-12
Substance
COPPER HISTIDINATE
Active strength
2.9 mg/1
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N211241-001ZYCUBOCOPPER HISTIDINATE2.9MG/VIALPOWDER / SUBCUTANEOUSRLD, RS2026-01-12

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N211241-001NCE2031-01-12
N211241-001ODE-5202033-01-12

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N211241-001ZYCUBO2.9MG/VIALPOWDER / SUBCUTANEOUSRLD, RS2026-01-12caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N211241-001ZYCUBO2.9MG/VIALPOWDER / SUBCUTANEOUSRLD, RS2026-01-12011fe1cb6892…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N211241-001ZYCUBO2.9MG/VIALPOWDER / SUBCUTANEOUSRLD, RS2026-01-12a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N211241-001NCE2031-01-12caaa826d4ba7…
2026-08-18 06:07:402026-07N211241-001ODE-5202033-01-12caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N211241-001NCE2031-01-12011fe1cb6892…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N211241-001NCE2031-01-12a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N211241-001ODE-5202033-01-12a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Zycubo
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
COPPER HISTIDINATE2.9 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9078K3MO9UInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2732219Internal RxNorm lookup
2732224Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e3aeefc2-f44d-4337-9c2e-3dba44a89e48Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42358-329-01Zycubo1 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,12
42358-329-01Zycubo1 in 1 VIAL, GLASSINJECTION, POWDER, LYOPHILIZED,12

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42358-329-01EA - Each42358-329b0ae7d55-02f2-4eab-9a31-6489ada1030112026-02-05

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ZycuboCOPPER HISTIDINATESentynl Therapeutics, Inc.e3aeefc2-f44d-4337-9c2e-3dba44a89e482026-01-12Warnings, Adverse reactionsExact identifier
application applno (NDA): 211241
application number: NDA211241
ndc (product): 42358-329

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2732219copper histidinate 2.9 MG InjectionPSNe3aeefc2-f44d-4337-9c2e-3dba44a89e482
2732224ZYCUBO 2.9 MG InjectionPSNe3aeefc2-f44d-4337-9c2e-3dba44a89e482
2732224copper histidinate 2.9 MG Injection [Zycubo]SBDe3aeefc2-f44d-4337-9c2e-3dba44a89e482
2732219copper histidinate 2.9 MG InjectionSCDe3aeefc2-f44d-4337-9c2e-3dba44a89e482
2732224Zycubo 2.9 MG InjectionSYe3aeefc2-f44d-4337-9c2e-3dba44a89e482

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
42358-329-01423580329011 VIAL, GLASS in 1 CARTON (42358-329-01) / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL, GLASS2026-01-26NoNoCurrent